Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

ATP synthase gamma chain

Gene

atpG

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF0 complex.

GO - Molecular functioni

  • proton-transporting ATPase activity, rotational mechanism Source: EcoCyc
  • proton-transporting ATP synthase activity, rotational mechanism Source: EcoCyc

GO - Biological processi

Keywordsi

Biological processATP synthesis, Hydrogen ion transport, Ion transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:ATPG-MONOMER.
MetaCyc:ATPG-MONOMER.

Protein family/group databases

TCDBi3.A.2.1.1. the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
ATP synthase gamma chain
Alternative name(s):
ATP synthase F1 sector gamma subunit
F-ATPase gamma subunit
Gene namesi
Name:atpG
Synonyms:papC, uncG
Ordered Locus Names:b3733, JW3711
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10104. atpG.

Subcellular locationi

GO - Cellular componenti

  • membrane Source: UniProtKB
  • plasma membrane Source: UniProtKB-SubCell
  • proton-transporting ATP synthase complex, catalytic core F(1) Source: EcoliWiki

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, CF(1), Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000732821 – 287ATP synthase gamma chainAdd BLAST287

Proteomic databases

PaxDbiP0ABA6.
PRIDEiP0ABA6.

Interactioni

Subunit structurei

F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a, b and c.1 Publication

Binary interactionsi

WithEntry#Exp.IntActNotes
atpCP0A6E65EBI-544306,EBI-544362

Protein-protein interaction databases

DIPiDIP-35938N.
IntActiP0ABA6. 15 interactors.
STRINGi316385.ECDH10B_3920.

Structurei

Secondary structure

1287
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi20 – 57Combined sources38
Turni61 – 63Combined sources3
Helixi66 – 68Combined sources3
Beta strandi74 – 81Combined sources8
Beta strandi84 – 86Combined sources3
Helixi91 – 108Combined sources18
Beta strandi112 – 119Combined sources8
Helixi120 – 129Combined sources10
Beta strandi133 – 137Combined sources5
Helixi147 – 161Combined sources15
Beta strandi168 – 177Combined sources10
Beta strandi180 – 190Combined sources11
Turni196 – 198Combined sources3
Beta strandi207 – 210Combined sources4
Helixi212 – 247Combined sources36

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1D8SX-ray4.40G1-287[»]
1FS0X-ray2.10G19-248[»]
3OAAX-ray3.26G/O/W/e2-287[»]
5T4Oelectron microscopy6.90G1-287[»]
5T4Pelectron microscopy7.77G1-287[»]
5T4Qelectron microscopy8.53G1-287[»]
ProteinModelPortaliP0ABA6.
SMRiP0ABA6.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0ABA6.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATPase gamma chain family.Curated

Phylogenomic databases

eggNOGiENOG4105J80. Bacteria.
COG0224. LUCA.
HOGENOMiHOG000215912.
InParanoidiP0ABA6.
KOiK02115.
PhylomeDBiP0ABA6.

Family and domain databases

CDDicd12151. F1-ATPase_gamma. 1 hit.
HAMAPiMF_00815. ATP_synth_gamma_bact. 1 hit.
InterProiView protein in InterPro
IPR035968. ATP_synth_F1_ATPase_gsu.
IPR000131. ATP_synth_F1_gsu.
IPR023632. ATP_synth_F1_gsu_CS.
PfamiView protein in Pfam
PF00231. ATP-synt. 1 hit.
PRINTSiPR00126. ATPASEGAMMA.
SUPFAMiSSF52943. SSF52943. 1 hit.
TIGRFAMsiTIGR01146. ATPsyn_F1gamma. 1 hit.
PROSITEiView protein in PROSITE
PS00153. ATPASE_GAMMA. 1 hit.

Sequencei

Sequence statusi: Complete.

P0ABA6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGAKEIRSK IASVQNTQKI TKAMEMVAAS KMRKSQDRMA ASRPYAETMR
60 70 80 90 100
KVIGHLAHGN LEYKHPYLED RDVKRVGYLV VSTDRGLCGG LNINLFKKLL
110 120 130 140 150
AEMKTWTDKG VQCDLAMIGS KGVSFFNSVG GNVVAQVTGM GDNPSLSELI
160 170 180 190 200
GPVKVMLQAY DEGRLDKLYI VSNKFINTMS QVPTISQLLP LPASDDDDLK
210 220 230 240 250
HKSWDYLYEP DPKALLDTLL RRYVESQVYQ GVVENLASEQ AARMVAMKAA
260 270 280
TDNGGSLIKE LQLVYNKARQ ASITQELTEI VSGAAAV
Length:287
Mass (Da):31,577
Last modified:July 21, 1986 - v1
Checksum:i2417A4B8FBDB8EF8
GO

Sequence cautioni

The sequence CAA23597 differs from that shown. Sequencing errors.Curated
The sequence CAA23597 differs from that shown. Reason: Frameshift at several positions.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X01631 Genomic DNA. Translation: CAA25781.1.
V00267 Genomic DNA. Translation: CAA23526.1.
J01594 Genomic DNA. Translation: AAA24736.1. Frameshift.
V00312 Genomic DNA. Translation: CAA23597.1. Sequence problems.
M25464 Genomic DNA. Translation: AAA83874.1.
L10328 Genomic DNA. Translation: AAA62085.1.
U00096 Genomic DNA. Translation: AAC76756.1.
AP009048 Genomic DNA. Translation: BAE77555.1.
M34095 Genomic DNA. Translation: AAA24742.1.
PIRiA01038. PWECG.
RefSeqiNP_418189.1. NC_000913.3.
WP_000896498.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76756; AAC76756; b3733.
BAE77555; BAE77555; BAE77555.
GeneIDi948243.
KEGGiecj:JW3711.
eco:b3733.
PATRICifig|1411691.4.peg.2967.

Similar proteinsi

Entry informationi

Entry nameiATPG_ECOLI
AccessioniPrimary (citable) accession number: P0ABA6
Secondary accession number(s): P00837, P00838, Q2M851
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: October 25, 2017
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families