P0AB58 (YCIM_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein YciM

Gene names

Name:	yciM
Ordered Locus Names:	b1280, JW1272

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	389 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities

Contains 6 TPR repeats.

Ontologies

Keywords
Domain	Repeat Signal TPR repeat Zinc-finger
Ligand	Metal-binding Zinc
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 16	16	Potential
	Chain	17 – 389	373	Uncharacterized protein YciM		PRO_0000013830
Regions
	Repeat	69 – 102	34	TPR 1
	Repeat	107 – 140	34	TPR 2
	Repeat	141 – 174	34	TPR 3
	Repeat	180 – 213	34	TPR 4
	Repeat	214 – 247	34	TPR 5
	Repeat	249 – 282	34	TPR 6
	Zinc finger	357 – 374	18	C4-type Potential

Sequences

	Sequence		Length	Mass (Da)
	P0AB58 [UniParc]. Last modified October 11, 2005. Version 1. Checksum: F4D1B9E2A526BCC3	FASTA	389	44,531
	10 20 30 40 50 60 MLELLFLLLP VAAAYGWYMG RRSAQQNKQD EANRLSRDYV AGVNFLLSNQ QDKAVDLFLD 70 80 90 100 110 120 MLKEDTGTVE AHLTLGNLFR SRGEVDRAIR IHQTLMESAS LTYEQRLLAI QQLGRDYMAA 130 140 150 160 170 180 GLYDRAEDMF NQLTDETDFR IGALQQLLQI YQATSEWQKA IDVAERLVKL GKDKQRVEIA 190 200 210 220 230 240 HFYCELALQH MASDDLDRAM TLLKKGAAAD KNSARVSIMM GRVFMAKGEY AKAVESLQRV 250 260 270 280 290 300 ISQDRELVSE TLEMLQTCYQ QLGKTAEWAE FLQRAVEENT GADAELMLAD IIEARDGSEA 310 320 330 340 350 360 AQVYITRQLQ RHPTMRVFHK LMDYHLNEAE EGRAKESLMV LRDMVGEKVR SKPRYRCQKC 370 380 GFTAYTLYWH CPSCRAWSTI KPIRGLDGL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A consensus sequence of three DNA replication terminus sites on the E. coli chromosome is highly homologous to the terR sites of the R6K plasmid." Hidaka M., Akiyama M., Horiuchi T. Cell 55:467-475(1988) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 308-389.
[2]	"A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map." Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T., Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T., Mizobuchi K., Mori H., Mori T., Motomura K. , Nakade S., Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y., Wada C., Yamamoto Y., Horiuchi T. DNA Res. 3:363-377(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[3]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[4]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[5]	"Detection of new genes in a bacterial genome using Markov models for three gene classes." Borodovsky M., McIninch J., Koonin E.V., Rudd K.E., Medigue C., Danchin A. Nucleic Acids Res. 23:3554-3562(1995) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M23250 Genomic DNA. No translation available. U00096 Genomic DNA. Translation: AAC74362.1. AP009048 Genomic DNA. Translation: BAA14834.1.
PIR	C64876.
RefSeq	NP_415796.1. NC_000913.2. YP_489548.1. NC_007779.1.
3D structure databases
ProteinModelPortal	P0AB58.
SMR	P0AB58. Positions 41-140.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-48161N.
IntAct	P0AB58. 1 interaction.
STRING	511145.b1280.
Proteomic databases
PaxDb	P0AB58.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC74362; AAC74362; b1280. BAA14834; BAA14834; BAA14834.
GeneID	12930406. 944858.
KEGG	ecj:Y75_p1255. eco:b1280.
PATRIC	32117822. VBIEscCol129921_1331.
Organism-specific databases
EchoBASE	EB2554.
EcoGene	EG12691. yciM.
Phylogenomic databases
eggNOG	COG2956.
HOGENOM	HOG000257806.
OMA	FRRRGEY.
ProtClustDB	PRK11788.
Enzyme and pathway databases
BioCyc	EcoCyc:EG12691-MONOMER. ECOL316407:JW1272-MONOMER.
Gene expression databases
Genevestigator	P0AB58.
Family and domain databases
Gene3D	1.25.40.10. 3 hits.
InterPro	IPR013026. TPR-contain_dom. IPR011990. TPR-like_helical. IPR013105. TPR_2. IPR019734. TPR_repeat. [Graphical view]
Pfam	PF07719. TPR_2. 1 hit. PF13176. TPR_7. 1 hit. [Graphical view]
SMART	SM00028. TPR. 3 hits. [Graphical view]
PROSITE	PS50005. TPR. 6 hits. PS50293. TPR_REGION. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YCIM_ECOLI

Accession

Primary (citable) accession number: P0AB58
Secondary accession number(s): P45576, P76836

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 11, 2005
Last sequence update:	October 11, 2005
Last modified:	May 1, 2013
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program