P0AB20 (HSPQ_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Heat shock protein HspQ

Gene names

Name:	hspQ
Synonyms:	yccV
Ordered Locus Names:	b0966, JW5970

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	105 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress. HAMAP-Rule MF_01194
Subcellular location	Cytoplasm Probable HAMAP-Rule MF_01194.
Induction	By heat shock. Transcribed by the sigma-32 subunit of RNA polymerase. Ref.4
Sequence similarities	Belongs to the HspQ family.

Ontologies

Keywords
Biological process	Stress response
Cellular component	Cytoplasm
Technical term	3D-structure Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Biological_process	response to heat Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	DNA binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 105

105

Heat shock protein HspQ HAMAP-Rule MF_01194

PRO_0000168795

Secondary structure

1

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105

Helix Strand Turn

Details...

Beta strand

11 – 14

4

Turn

15 – 17

3

Beta strand

20 – 27

8

Beta strand

51 – 57

7

Beta strand

63 – 69

7

Helix

70 – 72

3

Beta strand

73 – 75

3

Helix

85 – 94

10

Sequences

	Sequence		Length	Mass (Da)
	P0AB20 [UniParc]. Last modified June 26, 2007. Version 2. Checksum: B0F4FD95DCDF67AA	FASTA	105	11,779
	10 20 30 40 50 60 MIASKFGIGQ QVRHSLLGYL GVVVDIDPVY SLSEPSPDEL AVNDELRAAP WYHVVMEDDN 70 80 90 100 GLPVHTYLAE AQLSSELQDE HPEQPSMDEL AQTIRKQLQA PRLRN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map." Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K., Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S., Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K. , Mori H., Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G., Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M., Horiuchi T. DNA Res. 3:137-155(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]	"Novel heat shock protein HspQ stimulates the degradation of mutant DnaA protein in Escherichia coli." Shimuta T.R., Nakano K., Yamaguchi Y., Ozaki S., Fujimitsu K., Matsunaga C., Noguchi K., Emoto A., Katayama T. Genes Cells 9:1151-1166(2004) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE OF 1-6, CHARACTERIZATION, INDUCTION.
[5]	"Crystal structure of hypothetical protein from Escherichia coli." Shioi S., Maenaka K., Kohda D., Katayama T., Ueda T. Submitted (MAR-2004) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

U00096 Genomic DNA. Translation: AAC74052.2.
AP009048 Genomic DNA. Translation: BAA35731.1.

PIR

E64837.

RefSeq

NP_415486.4. NC_000913.2.
YP_489238.1. NC_007779.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1VBV	X-ray	2.70	A	1-105	[»]

ProteinModelPortal

P0AB20.

SMR

P0AB20. Positions 3-97.

ModBase

Search...

Protein-protein interaction databases

DIP

DIP-48155N.

STRING

511145.b0966.

Proteomic databases

PaxDb

P0AB20.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

AAC74052; AAC74052; b0966.
BAA35731; BAA35731; BAA35731.

GeneID

12933992.
945578.

KEGG

ecj:Y75_p0938.
eco:b0966.

PATRIC

32117153. VBIEscCol129921_1001.

Organism-specific databases

EchoBASE

EB3488.

EcoGene

EG13724. hspQ.

Phylogenomic databases

eggNOG

COG3785.

HOGENOM

HOG000139612.

KO

K11940.

OMA

GQQIRHK.

ProtClustDB

PRK14129.

Enzyme and pathway databases

BioCyc

EcoCyc:G6500-MONOMER.
ECOL316407:JW5970-MONOMER.

Gene expression databases

Genevestigator

P0AB20.

Family and domain databases

HAMAP

MF_01194. HspQ.

InterPro

IPR011722. Hemimethylated_DNA-bd_dom.
IPR022866. HspQ.
[Graphical view]

Pfam

PF08755. YccV-like. 1 hit.
[Graphical view]

SMART

SM00992. YccV-like. 1 hit.
[Graphical view]

SUPFAM

SSF141255. SSF141255. 1 hit.

TIGRFAMs

TIGR02097. yccV. 1 hit.

ProtoNet

Search...

Other

EvolutionaryTrace

P0AB20.

Entry information

Entry name

HSPQ_ECOLI

Accession

Primary (citable) accession number: P0AB20
Secondary accession number(s): P75875

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 11, 2005
Last sequence update:	June 26, 2007
Last modified:	May 1, 2013
This is version 59 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program