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Protein

Putative HNH nuclease YajD

Gene

yajD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Nuclease

Enzyme and pathway databases

BioCyciEcoCyc:EG11097-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative HNH nuclease YajD (EC:3.1.-.-)
Gene namesi
Name:yajD
Ordered Locus Names:b0410, JW0400
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11097. yajD.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: EcoCyc

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001686061 – 115Putative HNH nuclease YajDAdd BLAST115

Proteomic databases

PaxDbiP0AAQ2.
PRIDEiP0AAQ2.

Interactioni

Protein-protein interaction databases

BioGridi4262189. 12 interactors.
IntActiP0AAQ2. 11 interactors.
STRINGi511145.b0410.

Structurei

3D structure databases

ProteinModelPortaliP0AAQ2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 75HNHAdd BLAST49

Sequence similaritiesi

Belongs to the HNH nuclease family.Curated

Phylogenomic databases

eggNOGiENOG4105N1F. Bacteria.
ENOG4111U2E. LUCA.
HOGENOMiHOG000294005.
InParanoidiP0AAQ2.

Family and domain databases

InterProiView protein in InterPro
IPR002711. HNH.
IPR003615. HNH_nuc.
PfamiView protein in Pfam
PF01844. HNH. 1 hit.
SMARTiView protein in SMART
SM00507. HNHc. 1 hit.

Sequencei

Sequence statusi: Complete.

P0AAQ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAIIPKNYAR LESGYREKAL KIYPWVCGRC SREFVYSNLR ELTVHHIDHD
60 70 80 90 100
HTNNPEDGSN WELLCLYCHD HEHSKYTEAD QYGTTVIAGE DAQKDVGEAK
110
YNPFADLKAM MNKKK
Length:115
Mass (Da):13,364
Last modified:October 11, 2005 - v1
Checksum:i04D99E2E3FBAA0C7
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti109 – 115AMMNKKK → G in CAA39636 (PubMed:2170107).Curated7

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X56175 Genomic DNA. Translation: CAA39636.1.
U82664 Genomic DNA. Translation: AAB40166.1.
U00096 Genomic DNA. Translation: AAC73513.1.
AP009048 Genomic DNA. Translation: BAE76190.1.
PIRiB64770.
RefSeqiNP_414944.1. NC_000913.3.
WP_000974813.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73513; AAC73513; b0410.
BAE76190; BAE76190; BAE76190.
GeneIDi945051.
KEGGiecj:JW0400.
eco:b0410.
PATRICifig|511145.12.peg.426.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X56175 Genomic DNA. Translation: CAA39636.1.
U82664 Genomic DNA. Translation: AAB40166.1.
U00096 Genomic DNA. Translation: AAC73513.1.
AP009048 Genomic DNA. Translation: BAE76190.1.
PIRiB64770.
RefSeqiNP_414944.1. NC_000913.3.
WP_000974813.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AAQ2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262189. 12 interactors.
IntActiP0AAQ2. 11 interactors.
STRINGi511145.b0410.

Proteomic databases

PaxDbiP0AAQ2.
PRIDEiP0AAQ2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73513; AAC73513; b0410.
BAE76190; BAE76190; BAE76190.
GeneIDi945051.
KEGGiecj:JW0400.
eco:b0410.
PATRICifig|511145.12.peg.426.

Organism-specific databases

EchoBASEiEB1089.
EcoGeneiEG11097. yajD.

Phylogenomic databases

eggNOGiENOG4105N1F. Bacteria.
ENOG4111U2E. LUCA.
HOGENOMiHOG000294005.
InParanoidiP0AAQ2.

Enzyme and pathway databases

BioCyciEcoCyc:EG11097-MONOMER.

Miscellaneous databases

PROiPR:P0AAQ2.

Family and domain databases

InterProiView protein in InterPro
IPR002711. HNH.
IPR003615. HNH_nuc.
PfamiView protein in Pfam
PF01844. HNH. 1 hit.
SMARTiView protein in SMART
SM00507. HNHc. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYAJD_ECOLI
AccessioniPrimary (citable) accession number: P0AAQ2
Secondary accession number(s): P19678, P77666, Q2MC16
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2005
Last sequence update: October 11, 2005
Last modified: June 7, 2017
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.