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Protein

Inhibitor of hydrogen peroxide resistance

Gene

iprA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in oxidative stress resistance.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi163 – 182H-T-H motifUniRule annotationAdd BLAST20

Keywordsi

Biological processStress response

Enzyme and pathway databases

BioCyciEcoCyc:G6226-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Inhibitor of hydrogen peroxide resistanceUniRule annotation
Gene namesi
Name:iprAUniRule annotation
Synonyms:yaiV
Ordered Locus Names:b0375, JW0366
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13607 yaiV

Pathology & Biotechi

Disruption phenotypei

Deletion mutants display increased resistance to oxidative stress and increased catalase activity.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001685961 – 207Inhibitor of hydrogen peroxide resistanceAdd BLAST207

Proteomic databases

PaxDbiP0AAP5
PRIDEiP0AAP5

Interactioni

Protein-protein interaction databases

BioGridi4259481, 153 interactors
IntActiP0AAP5, 3 interactors
STRINGi316385.ECDH10B_0332

Structurei

3D structure databases

ProteinModelPortaliP0AAP5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the IprA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108PNB Bacteria
ENOG410ZQUT LUCA
HOGENOMiHOG000117456

Family and domain databases

HAMAPiMF_02072 IprA, 1 hit
InterProiView protein in InterPro
IPR018490 cNMP-bd-like
IPR034719 IprA
SUPFAMiSSF51206 SSF51206, 1 hit

Sequencei

Sequence statusi: Complete.

P0AAP5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSVVKPLQE FGKLDKCLSR YGTRFEFNNE KQVIFSSDVN NEDTFVILEG
60 70 80 90 100
VISLRREENV LIGITQAPYI MGLADGLMKN DIPYKLISEG NCTGYHLPAK
110 120 130 140 150
QTITLIEQNQ LWRDAFYWLA WQNRILELRD VQLIGHNSYE QIRATLLSMI
160 170 180 190 200
DWNEELRSRI GVMNYIHQRT RISRSVVAEV LAALRKGGYI EMNKGKLVAI

NRLPSEY
Length:207
Mass (Da):23,956
Last modified:November 24, 2009 - v2
Checksum:iE58258DC6F00E505
GO

Sequence cautioni

The sequence AAB18098 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAE76156 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U73857 Genomic DNA Translation: AAB18098.1 Different initiation.
U00096 Genomic DNA Translation: AAC73478.2
AP009048 Genomic DNA Translation: BAE76156.1 Different initiation.
PIRiG64765
RefSeqiNP_414909.2, NC_000913.3
WP_001295335.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73478; AAC73478; b0375
BAE76156; BAE76156; BAE76156
GeneIDi946902
KEGGiecj:JW0366
eco:b0375
PATRICifig|1411691.4.peg.1904

Entry informationi

Entry nameiIPRA_ECOLI
AccessioniPrimary (citable) accession number: P0AAP5
Secondary accession number(s): P77723, Q2MC50
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2005
Last sequence update: November 24, 2009
Last modified: April 25, 2018
This is version 82 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families
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