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Protein

Transcriptional repressor FrmR

Gene

frmR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Repressor of the frmRAB operon.1 Publication

GO - Molecular functioni

GO - Biological processi

  • negative regulation of transcription, DNA-templated Source: EcoCyc
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionDNA-binding, Repressor
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciEcoCyc:G6209-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional repressor FrmR
Gene namesi
Name:frmR
Synonyms:yaiN
Ordered Locus Names:b0357, JW0348
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13296 frmR

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001685911 – 91Transcriptional repressor FrmRAdd BLAST91

Proteomic databases

PaxDbiP0AAP3
PRIDEiP0AAP3

Expressioni

Inductioni

Induced by formaldehyde. Negatively autoregulated.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi426180413 interactors.
DIPiDIP-48245N
IntActiP0AAP3 2 interactors.
STRINGi316385.ECDH10B_0312

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5LBMX-ray2.70A/B/C/D1-91[»]
ProteinModelPortaliP0AAP3
SMRiP0AAP3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FrmR/RcnR family.Curated

Phylogenomic databases

eggNOGiENOG4105VEG Bacteria
COG1937 LUCA
HOGENOMiHOG000023914
InParanoidiP0AAP3
OMAiDCGPILQ
PhylomeDBiP0AAP3

Family and domain databases

Gene3Di1.20.58.10001 hit
InterProiView protein in InterPro
IPR003735 Metal_Tscrpt_repr
IPR038390 Metal_Tscrpt_repr_sf
PANTHERiPTHR33677 PTHR33677, 1 hit
PfamiView protein in Pfam
PF02583 Trns_repr_metal, 1 hit

Sequencei

Sequence statusi: Complete.

P0AAP3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSTPEEKKK VLTRVRRIRG QIDALERSLE GDAECRAILQ QIAAVRGAAN
60 70 80 90
GLMAEVLESH IRETFDRNDC YSREVSQSVD DTIELVRAYL K
Length:91
Mass (Da):10,318
Last modified:October 11, 2005 - v1
Checksum:i23305017AAB2C22D
GO

Sequence cautioni

The sequence AAB18082 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence D85613 differs from that shown. Reason: Frameshift at position 20.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D85613 Genomic DNA No translation available.
U73857 Genomic DNA Translation: AAB18082.1 Different initiation.
U00096 Genomic DNA Translation: AAC73460.2
AP009048 Genomic DNA Translation: BAE76139.1
RefSeqiNP_414891.4, NC_000913.3
WP_001141271.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73460; AAC73460; b0357
BAE76139; BAE76139; BAE76139
GeneIDi944986
KEGGiecj:JW0348
eco:b0357
PATRICifig|1411691.4.peg.1921

Similar proteinsi

Entry informationi

Entry nameiFRMR_ECOLI
AccessioniPrimary (citable) accession number: P0AAP3
Secondary accession number(s): P55756, P77584, Q2MC67
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2005
Last sequence update: October 11, 2005
Last modified: March 28, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome