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Protein

Hydrogenase-2 operon protein HybE

Gene

hybE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • preprotein binding Source: EcoCyc

GO - Biological processi

  • protein maturation Source: EcoCyc

Enzyme and pathway databases

BioCyciEcoCyc:EG11803-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Hydrogenase-2 operon protein HybE
Gene namesi
Name:hybE
Ordered Locus Names:b2992, JW2960
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11803 hybE

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002014261 – 162Hydrogenase-2 operon protein HybEAdd BLAST162

Proteomic databases

PaxDbiP0AAN1
PRIDEiP0AAN1

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
hybOP697415EBI-552588,EBI-552619

GO - Molecular functioni

  • preprotein binding Source: EcoCyc

Protein-protein interaction databases

BioGridi4262373, 13 interactors
DIPiDIP-35795N
IntActiP0AAN1, 7 interactors
MINTiP0AAN1
STRINGi316385.ECDH10B_3169

Structurei

Secondary structure

1162
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi4 – 6Combined sources3
Helixi13 – 23Combined sources11
Helixi29 – 31Combined sources3
Beta strandi41 – 48Combined sources8
Beta strandi51 – 57Combined sources7
Beta strandi62 – 68Combined sources7
Beta strandi73 – 75Combined sources3
Beta strandi82 – 85Combined sources4
Beta strandi92 – 99Combined sources8
Turni100 – 102Combined sources3
Beta strandi103 – 111Combined sources9
Helixi120 – 135Combined sources16

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2KC5NMR-A1-162[»]
ProteinModelPortaliP0AAN1
SMRiP0AAN1
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0AAN1

Family & Domainsi

Sequence similaritiesi

Belongs to the HupJ family.Curated

Phylogenomic databases

eggNOGiENOG4108WGS Bacteria
ENOG4111JT6 LUCA
HOGENOMiHOG000278778
InParanoidiP0AAN1
OMAiLTPWMIS

Family and domain databases

Gene3Di3.30.1460.40, 1 hit
InterProiView protein in InterPro
IPR023994 NiFe-hyd_HybE
IPR038530 NiFe-hyd_HybE_sf
PfamiView protein in Pfam
PF11939 NiFe-hyd_HybE, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD008308 PD008308, 1 hit
TIGRFAMsiTIGR03993 hydrog_HybE, 1 hit

Sequencei

Sequence statusi: Complete.

P0AAN1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEEIAGFQT SPKAQVQAAF EEIARRSMHD LSFLHPSMPV YVSDFTLFEG
60 70 80 90 100
QWTGCVITPW MLSAVIFPGP DQLWPLRKVS EKIGLQLPYG TMTFTVGELD
110 120 130 140 150
GVSQYLSCSL MSPLSHSMSI EEGQRLTDDC ARMILSLPVT NPDVPHAGRR
160
ALLFGRRSGE NA
Length:162
Mass (Da):17,964
Last modified:October 11, 2005 - v1
Checksum:iCFDAEA3D47BE9516
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti7G → A in AAA21593 (PubMed:8021226).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U09177 Genomic DNA Translation: AAA21593.1
U28377 Genomic DNA Translation: AAA69159.1
U00096 Genomic DNA Translation: AAC76028.1
AP009048 Genomic DNA Translation: BAE77053.1
PIRiF65085
RefSeqiNP_417466.1, NC_000913.3
WP_000134014.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC76028; AAC76028; b2992
BAE77053; BAE77053; BAE77053
GeneIDi947483
KEGGiecj:JW2960
eco:b2992
PATRICifig|1411691.4.peg.3737

Similar proteinsi

Entry informationi

Entry nameiHYBE_ECOLI
AccessioniPrimary (citable) accession number: P0AAN1
Secondary accession number(s): P37183, Q2M9K3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2005
Last sequence update: October 11, 2005
Last modified: March 28, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
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Main funding by: National Institutes of Health