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P0AAM7

- HYBG_ECOLI

UniProt

P0AAM7 - HYBG_ECOLI

Protein

Hydrogenase-2 operon protein HybG

Gene

hybG

Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    May have a specific role in the maturation of the large subunits of HYD1 and HYD2.

    GO - Molecular functioni

    1. protein binding Source: IntAct

    GO - Biological processi

    1. chaperone-mediated protein complex assembly Source: EcoCyc

    Enzyme and pathway databases

    BioCyciEcoCyc:EG11805-MONOMER.
    ECOL316407:JW2958-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Hydrogenase-2 operon protein HybG
    Gene namesi
    Name:hybG
    Ordered Locus Names:b2990, JW2958
    OrganismiEscherichia coli (strain K12)
    Taxonomic identifieri83333 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

    Organism-specific databases

    EcoGeneiEG11805. hybG.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 8282Hydrogenase-2 operon protein HybGPRO_0000201403Add
    BLAST

    Expressioni

    Gene expression databases

    GenevestigatoriP0AAM7.

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    hypDP241927EBI-562426,EBI-552711

    Protein-protein interaction databases

    DIPiDIP-36429N.
    IntActiP0AAM7. 10 interactions.
    STRINGi511145.b2990.

    Structurei

    3D structure databases

    ProteinModelPortaliP0AAM7.
    SMRiP0AAM7. Positions 1-75.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the HupF/HypC family.Curated

    Phylogenomic databases

    eggNOGiCOG0298.
    HOGENOMiHOG000278755.
    KOiK04653.
    OMAiIVEITDI.
    OrthoDBiEOG6GR3F3.
    PhylomeDBiP0AAM7.

    Family and domain databases

    InterProiIPR019812. Hydgase_assmbl_chp_CS.
    IPR001109. Hydrogenase_HupF/HypC.
    [Graphical view]
    PfamiPF01455. HupF_HypC. 1 hit.
    [Graphical view]
    PRINTSiPR00445. HUPFHYPC.
    TIGRFAMsiTIGR00074. hypC_hupF. 1 hit.
    PROSITEiPS01097. HUPF_HYPC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P0AAM7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MCIGVPGQVL AVGEDIHQLA QVEVCGIKRD VNIALICEGN PADLLGQWVL   50
    VHVGFAMSII DEDEAKATLD ALRQMDYDIT SA 82
    Length:82
    Mass (Da):8,808
    Last modified:October 11, 2005 - v1
    Checksum:i8E9736BFC4EFD626
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U09177 Genomic DNA. Translation: AAA21595.1.
    U28377 Genomic DNA. Translation: AAA69157.1.
    U00096 Genomic DNA. Translation: AAC76026.1.
    AP009048 Genomic DNA. Translation: BAE77051.1.
    PIRiG55516.
    RefSeqiNP_417464.1. NC_000913.3.
    YP_491187.1. NC_007779.1.

    Genome annotation databases

    EnsemblBacteriaiAAC76026; AAC76026; b2990.
    BAE77051; BAE77051; BAE77051.
    GeneIDi12933378.
    948020.
    KEGGiecj:Y75_p2919.
    eco:b2990.
    PATRICi32121396. VBIEscCol129921_3085.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U09177 Genomic DNA. Translation: AAA21595.1 .
    U28377 Genomic DNA. Translation: AAA69157.1 .
    U00096 Genomic DNA. Translation: AAC76026.1 .
    AP009048 Genomic DNA. Translation: BAE77051.1 .
    PIRi G55516.
    RefSeqi NP_417464.1. NC_000913.3.
    YP_491187.1. NC_007779.1.

    3D structure databases

    ProteinModelPortali P0AAM7.
    SMRi P0AAM7. Positions 1-75.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    DIPi DIP-36429N.
    IntActi P0AAM7. 10 interactions.
    STRINGi 511145.b2990.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC76026 ; AAC76026 ; b2990 .
    BAE77051 ; BAE77051 ; BAE77051 .
    GeneIDi 12933378.
    948020.
    KEGGi ecj:Y75_p2919.
    eco:b2990.
    PATRICi 32121396. VBIEscCol129921_3085.

    Organism-specific databases

    EchoBASEi EB1753.
    EcoGenei EG11805. hybG.

    Phylogenomic databases

    eggNOGi COG0298.
    HOGENOMi HOG000278755.
    KOi K04653.
    OMAi IVEITDI.
    OrthoDBi EOG6GR3F3.
    PhylomeDBi P0AAM7.

    Enzyme and pathway databases

    BioCyci EcoCyc:EG11805-MONOMER.
    ECOL316407:JW2958-MONOMER.

    Miscellaneous databases

    PROi P0AAM7.

    Gene expression databases

    Genevestigatori P0AAM7.

    Family and domain databases

    InterProi IPR019812. Hydgase_assmbl_chp_CS.
    IPR001109. Hydrogenase_HupF/HypC.
    [Graphical view ]
    Pfami PF01455. HupF_HypC. 1 hit.
    [Graphical view ]
    PRINTSi PR00445. HUPFHYPC.
    TIGRFAMsi TIGR00074. hypC_hupF. 1 hit.
    PROSITEi PS01097. HUPF_HYPC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning, sequencing, and mutational analysis of the hyb operon encoding Escherichia coli hydrogenase 2."
      Menon N.K., Chatelus C.Y., Dervartanian M., Wendt J.C., Shanmugam K.T., Peck H.D. Jr., Przybyla A.E.
      J. Bacteriol. 176:4416-4423(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: K12 / TG1.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / MG1655 / ATCC 47076.
    3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
      Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
      Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

    Entry informationi

    Entry nameiHYBG_ECOLI
    AccessioniPrimary (citable) accession number: P0AAM7
    Secondary accession number(s): P37185, Q2M9K5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 11, 2005
    Last sequence update: October 11, 2005
    Last modified: October 1, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Escherichia coli
      Escherichia coli (strain K12): entries and cross-references to EcoGene
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3