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Protein

Hydrogenase-2 operon protein HybG

Gene

hybG

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

May have a specific role in the maturation of the large subunits of HYD1 and HYD2.

GO - Biological processi

  • chaperone-mediated protein complex assembly Source: EcoCyc
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:EG11805-MONOMER.
ECOL316407:JW2958-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Hydrogenase-2 operon protein HybG
Gene namesi
Name:hybG
Ordered Locus Names:b2990, JW2958
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000318 Componenti: Chromosome UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11805. hybG.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 8282Hydrogenase-2 operon protein HybGPRO_0000201403Add
BLAST

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
hypDP241927EBI-562426,EBI-552711

Protein-protein interaction databases

DIPiDIP-36429N.
IntActiP0AAM7. 10 interactions.
STRINGi511145.b2990.

Structurei

3D structure databases

ProteinModelPortaliP0AAM7.
SMRiP0AAM7. Positions 1-75.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the HupF/HypC family.Curated

Phylogenomic databases

eggNOGiCOG0298.
HOGENOMiHOG000278755.
InParanoidiP0AAM7.
KOiK04653.
OMAiFAMNRIN.
OrthoDBiEOG6GR3F3.
PhylomeDBiP0AAM7.

Family and domain databases

InterProiIPR019812. Hydgase_assmbl_chp_CS.
IPR001109. Hydrogenase_HupF/HypC.
[Graphical view]
PfamiPF01455. HupF_HypC. 1 hit.
[Graphical view]
PRINTSiPR00445. HUPFHYPC.
TIGRFAMsiTIGR00074. hypC_hupF. 1 hit.
PROSITEiPS01097. HUPF_HYPC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AAM7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCIGVPGQVL AVGEDIHQLA QVEVCGIKRD VNIALICEGN PADLLGQWVL
60 70 80
VHVGFAMSII DEDEAKATLD ALRQMDYDIT SA
Length:82
Mass (Da):8,808
Last modified:October 11, 2005 - v1
Checksum:i8E9736BFC4EFD626
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U09177 Genomic DNA. Translation: AAA21595.1.
U28377 Genomic DNA. Translation: AAA69157.1.
U00096 Genomic DNA. Translation: AAC76026.1.
AP009048 Genomic DNA. Translation: BAE77051.1.
PIRiG55516.
RefSeqiNP_417464.1. NC_000913.3.
WP_000334896.1. NZ_CP010445.1.

Genome annotation databases

EnsemblBacteriaiAAC76026; AAC76026; b2990.
BAE77051; BAE77051; BAE77051.
GeneIDi948020.
KEGGieco:b2990.
PATRICi32121396. VBIEscCol129921_3085.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U09177 Genomic DNA. Translation: AAA21595.1.
U28377 Genomic DNA. Translation: AAA69157.1.
U00096 Genomic DNA. Translation: AAC76026.1.
AP009048 Genomic DNA. Translation: BAE77051.1.
PIRiG55516.
RefSeqiNP_417464.1. NC_000913.3.
WP_000334896.1. NZ_CP010445.1.

3D structure databases

ProteinModelPortaliP0AAM7.
SMRiP0AAM7. Positions 1-75.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-36429N.
IntActiP0AAM7. 10 interactions.
STRINGi511145.b2990.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76026; AAC76026; b2990.
BAE77051; BAE77051; BAE77051.
GeneIDi948020.
KEGGieco:b2990.
PATRICi32121396. VBIEscCol129921_3085.

Organism-specific databases

EchoBASEiEB1753.
EcoGeneiEG11805. hybG.

Phylogenomic databases

eggNOGiCOG0298.
HOGENOMiHOG000278755.
InParanoidiP0AAM7.
KOiK04653.
OMAiFAMNRIN.
OrthoDBiEOG6GR3F3.
PhylomeDBiP0AAM7.

Enzyme and pathway databases

BioCyciEcoCyc:EG11805-MONOMER.
ECOL316407:JW2958-MONOMER.

Miscellaneous databases

PROiP0AAM7.

Family and domain databases

InterProiIPR019812. Hydgase_assmbl_chp_CS.
IPR001109. Hydrogenase_HupF/HypC.
[Graphical view]
PfamiPF01455. HupF_HypC. 1 hit.
[Graphical view]
PRINTSiPR00445. HUPFHYPC.
TIGRFAMsiTIGR00074. hypC_hupF. 1 hit.
PROSITEiPS01097. HUPF_HYPC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning, sequencing, and mutational analysis of the hyb operon encoding Escherichia coli hydrogenase 2."
    Menon N.K., Chatelus C.Y., Dervartanian M., Wendt J.C., Shanmugam K.T., Peck H.D. Jr., Przybyla A.E.
    J. Bacteriol. 176:4416-4423(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12 / TG1.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiHYBG_ECOLI
AccessioniPrimary (citable) accession number: P0AAM7
Secondary accession number(s): P37185, Q2M9K5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2005
Last sequence update: October 11, 2005
Last modified: July 22, 2015
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.