P0AAM7 (HYBG_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Hydrogenase-2 operon protein HybG

Gene names

Name:	hybG
Ordered Locus Names:	b2990, JW2958

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	82 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May have a specific role in the maturation of the large subunits of HYD1 and HYD2.
Sequence similarities	Belongs to the HupF/HypC family.

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	chaperone-mediated protein complex assembly Inferred from direct assay PubMed 11292801. Source: EcoCyc
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 82	82	Hydrogenase-2 operon protein HybG		PRO_0000201403

Sequences

	Sequence		Length	Mass (Da)
	P0AAM7 [UniParc]. Last modified October 11, 2005. Version 1. Checksum: 8E9736BFC4EFD626	FASTA	82	8,808
	10 20 30 40 50 60 MCIGVPGQVL AVGEDIHQLA QVEVCGIKRD VNIALICEGN PADLLGQWVL VHVGFAMSII 70 80 DEDEAKATLD ALRQMDYDIT SA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cloning, sequencing, and mutational analysis of the hyb operon encoding Escherichia coli hydrogenase 2." Menon N.K., Chatelus C.Y., Dervartanian M., Wendt J.C., Shanmugam K.T., Peck H.D. Jr., Przybyla A.E. J. Bacteriol. 176:4416-4423(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: K12 / TG1.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U09177 Genomic DNA. Translation: AAA21595.1. U28377 Genomic DNA. Translation: AAA69157.1. U00096 Genomic DNA. Translation: AAC76026.1. AP009048 Genomic DNA. Translation: BAE77051.1.
PIR	G55516.
RefSeq	NP_417464.1. NC_000913.2. YP_491187.1. NC_007779.1.
3D structure databases
ProteinModelPortal	P0AAM7.
SMR	P0AAM7. Positions 1-75.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-36429N.
IntAct	P0AAM7. 5 interactions.
STRING	511145.b2990.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC76026; AAC76026; b2990. BAE77051; BAE77051; BAE77051.
GeneID	12933378. 948020.
KEGG	ecj:Y75_p2919. eco:b2990.
PATRIC	32121396. VBIEscCol129921_3085.
Organism-specific databases
EchoBASE	EB1753.
EcoGene	EG11805. hybG.
Phylogenomic databases
eggNOG	COG0298.
HOGENOM	HOG000278755.
KO	K04653.
OMA	REVNLAC.
ProtClustDB	PRK10413.
Enzyme and pathway databases
BioCyc	EcoCyc:EG11805-MONOMER. ECOL316407:JW2958-MONOMER.
Gene expression databases
Genevestigator	P0AAM7.
Family and domain databases
InterPro	IPR019812. Hydgase_assmbl_chp_CS. IPR001109. Hydrogenase_HupF/HypC. [Graphical view]
Pfam	PF01455. HupF_HypC. 1 hit. [Graphical view]
PRINTS	PR00445. HUPFHYPC.
TIGRFAMs	TIGR00074. hypC_hupF. 1 hit.
PROSITE	PS01097. HUPF_HYPC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HYBG_ECOLI

Accession

Primary (citable) accession number: P0AAM7
Secondary accession number(s): P37185, Q2M9K5

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 11, 2005
Last sequence update:	October 11, 2005
Last modified:	May 1, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program