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P0AAM1

- CYBH_ECOLI

UniProt

P0AAM1 - CYBH_ECOLI

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Protein
Probable Ni/Fe-hydrogenase 1 B-type cytochrome subunit
Gene
hyaC, b0974, JW0956
Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Probable b-type cytochrome.

GO - Molecular functioni

  1. electron carrier activity Source: InterPro
  2. iron ion binding Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. respiratory electron transport chain Source: InterPro
  2. transport Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Electron transport, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Enzyme and pathway databases

BioCyciEcoCyc:HYAC-MONOMER.
ECOL316407:JW0956-MONOMER.
MetaCyc:HYAC-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable Ni/Fe-hydrogenase 1 B-type cytochrome subunit
Gene namesi
Name:hyaC
Ordered Locus Names:b0974, JW0956
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

Organism-specific databases

EcoGeneiEG10470. hyaC.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 1919Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei20 – 4021Helical; Reviewed prediction
Add
BLAST
Topological domaini41 – 6323Periplasmic Reviewed prediction
Add
BLAST
Transmembranei64 – 8421Helical; Reviewed prediction
Add
BLAST
Topological domaini85 – 13046Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei131 – 15121Helical; Reviewed prediction
Add
BLAST
Topological domaini152 – 18534Periplasmic Reviewed prediction
Add
BLAST
Transmembranei186 – 20318Helical; Reviewed prediction
Add
BLAST
Topological domaini204 – 23532Cytoplasmic Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 235235Probable Ni/Fe-hydrogenase 1 B-type cytochrome subunit
PRO_0000201384Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriP0AAM1.

Interactioni

Protein-protein interaction databases

DIPiDIP-35859N.
IntActiP0AAM1. 1 interaction.
STRINGi511145.b0974.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi20 – 4021
Helixi50 – 523
Helixi55 – 8127
Turni82 – 854
Turni106 – 1083
Beta strandi109 – 1135
Turni130 – 1323
Helixi133 – 15119
Turni152 – 1554
Helixi161 – 1633
Helixi164 – 17310
Helixi178 – 20730

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4GD3X-ray3.30A/B1-235[»]
ProteinModelPortaliP0AAM1.

Family & Domainsi

Sequence similaritiesi

Belongs to the HupC/HyaC/HydC family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1969.
HOGENOMiHOG000291339.
KOiK03620.
OMAiYWALVGN.
OrthoDBiEOG6B8XHX.
PhylomeDBiP0AAM1.

Family and domain databases

InterProiIPR011577. Cyt_b561_bac/Ni-Hgenase.
IPR016174. Di-haem_cyt_TM.
IPR000516. Ni-dep_Hydgase_cyt-B.
[Graphical view]
PfamiPF00033. Cytochrom_B_N. 1 hit.
PF01292. Ni_hydr_CYTB. 1 hit.
[Graphical view]
PRINTSiPR00161. NIHGNASECYTB.
SUPFAMiSSF81342. SSF81342. 1 hit.
TIGRFAMsiTIGR02125. CytB-hydogenase. 1 hit.
PROSITEiPS00882. NI_HGENASE_CYTB_1. 1 hit.
PS00883. NI_HGENASE_CYTB_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AAM1-1 [UniParc]FASTAAdd to Basket

« Hide

MQQKSDNVVS HYVFEAPVRI WHWLTVLCMA VLMVTGYFIG KPLPSVSGEA    50
TYLFYMGYIR LIHFSAGMVF TVVLLMRIYW AFVGNRYSRE LFIVPVWRKS 100
WWQGVWYEIR WYLFLAKRPS ADIGHNPIAQ AAMFGYFLMS VFMIITGFAL 150
YSEHSQYAIF APFRYVVEFF YWTGGNSMDI HSWHRLGMWL IGAFVIGHVY 200
MALREDIMSD DTVISTMVNG YRSHKFGKIS NKERS 235
Length:235
Mass (Da):27,597
Last modified:October 11, 2005 - v1
Checksum:i98048DC800AB02C7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M34825 Genomic DNA. Translation: AAA23999.1.
U00096 Genomic DNA. Translation: AAC74059.1.
AP009048 Genomic DNA. Translation: BAA35739.1.
PIRiJV0074. BVECYC.
RefSeqiNP_415493.1. NC_000913.3.
YP_489245.1. NC_007779.1.

Genome annotation databases

EnsemblBacteriaiAAC74059; AAC74059; b0974.
BAA35739; BAA35739; BAA35739.
GeneIDi12931050.
945581.
KEGGiecj:Y75_p0945.
eco:b0974.
PATRICi32117169. VBIEscCol129921_1008.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M34825 Genomic DNA. Translation: AAA23999.1 .
U00096 Genomic DNA. Translation: AAC74059.1 .
AP009048 Genomic DNA. Translation: BAA35739.1 .
PIRi JV0074. BVECYC.
RefSeqi NP_415493.1. NC_000913.3.
YP_489245.1. NC_007779.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4GD3 X-ray 3.30 A/B 1-235 [» ]
ProteinModelPortali P0AAM1.
ModBasei Search...

Protein-protein interaction databases

DIPi DIP-35859N.
IntActi P0AAM1. 1 interaction.
STRINGi 511145.b0974.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC74059 ; AAC74059 ; b0974 .
BAA35739 ; BAA35739 ; BAA35739 .
GeneIDi 12931050.
945581.
KEGGi ecj:Y75_p0945.
eco:b0974.
PATRICi 32117169. VBIEscCol129921_1008.

Organism-specific databases

EchoBASEi EB0465.
EcoGenei EG10470. hyaC.

Phylogenomic databases

eggNOGi COG1969.
HOGENOMi HOG000291339.
KOi K03620.
OMAi YWALVGN.
OrthoDBi EOG6B8XHX.
PhylomeDBi P0AAM1.

Enzyme and pathway databases

BioCyci EcoCyc:HYAC-MONOMER.
ECOL316407:JW0956-MONOMER.
MetaCyc:HYAC-MONOMER.

Miscellaneous databases

PROi P0AAM1.

Gene expression databases

Genevestigatori P0AAM1.

Family and domain databases

InterProi IPR011577. Cyt_b561_bac/Ni-Hgenase.
IPR016174. Di-haem_cyt_TM.
IPR000516. Ni-dep_Hydgase_cyt-B.
[Graphical view ]
Pfami PF00033. Cytochrom_B_N. 1 hit.
PF01292. Ni_hydr_CYTB. 1 hit.
[Graphical view ]
PRINTSi PR00161. NIHGNASECYTB.
SUPFAMi SSF81342. SSF81342. 1 hit.
TIGRFAMsi TIGR02125. CytB-hydogenase. 1 hit.
PROSITEi PS00882. NI_HGENASE_CYTB_1. 1 hit.
PS00883. NI_HGENASE_CYTB_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning and sequencing of a putative Escherichia coli [NiFe] hydrogenase-1 operon containing six open reading frames."
    Menon N.K., Robbins J., Peck H.D. Jr., Chatelus C.Y., Choi E.-S., Przybyla A.E.
    J. Bacteriol. 172:1969-1977(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  5. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiCYBH_ECOLI
AccessioniPrimary (citable) accession number: P0AAM1
Secondary accession number(s): P19929
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2005
Last sequence update: October 11, 2005
Last modified: June 11, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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