Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P0AAM1

- CYBH_ECOLI

UniProt

P0AAM1 - CYBH_ECOLI

Protein

Probable Ni/Fe-hydrogenase 1 B-type cytochrome subunit

Gene

hyaC

Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 75 (01 Oct 2014)
      Sequence version 1 (11 Oct 2005)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Probable b-type cytochrome.

    GO - Molecular functioni

    1. electron carrier activity Source: InterPro
    2. iron ion binding Source: InterPro

    GO - Biological processi

    1. respiratory electron transport chain Source: InterPro
    2. transport Source: InterPro

    Keywords - Biological processi

    Electron transport, Transport

    Keywords - Ligandi

    Heme, Iron, Metal-binding

    Enzyme and pathway databases

    BioCyciEcoCyc:HYAC-MONOMER.
    ECOL316407:JW0956-MONOMER.
    MetaCyc:HYAC-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable Ni/Fe-hydrogenase 1 B-type cytochrome subunit
    Gene namesi
    Name:hyaC
    Ordered Locus Names:b0974, JW0956
    OrganismiEscherichia coli (strain K12)
    Taxonomic identifieri83333 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

    Organism-specific databases

    EcoGeneiEG10470. hyaC.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 235235Probable Ni/Fe-hydrogenase 1 B-type cytochrome subunitPRO_0000201384Add
    BLAST

    Expressioni

    Gene expression databases

    GenevestigatoriP0AAM1.

    Interactioni

    Protein-protein interaction databases

    DIPiDIP-35859N.
    IntActiP0AAM1. 1 interaction.
    STRINGi511145.b0974.

    Structurei

    Secondary structure

    1
    235
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi20 – 4021
    Helixi50 – 523
    Helixi55 – 8127
    Turni82 – 854
    Turni106 – 1083
    Beta strandi109 – 1135
    Turni130 – 1323
    Helixi133 – 15119
    Turni152 – 1554
    Helixi161 – 1633
    Helixi164 – 17310
    Helixi178 – 20730

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4GD3X-ray3.30A/B1-235[»]
    ProteinModelPortaliP0AAM1.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 1919CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini41 – 6323PeriplasmicSequence AnalysisAdd
    BLAST
    Topological domaini85 – 13046CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini152 – 18534PeriplasmicSequence AnalysisAdd
    BLAST
    Topological domaini204 – 23532CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei20 – 4021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei64 – 8421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei131 – 15121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei186 – 20318HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the HupC/HyaC/HydC family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG1969.
    HOGENOMiHOG000291339.
    KOiK03620.
    OMAiYWALVGN.
    OrthoDBiEOG6B8XHX.
    PhylomeDBiP0AAM1.

    Family and domain databases

    InterProiIPR011577. Cyt_b561_bac/Ni-Hgenase.
    IPR016174. Di-haem_cyt_TM.
    IPR000516. Ni-dep_Hydgase_cyt-B.
    [Graphical view]
    PfamiPF00033. Cytochrom_B_N. 1 hit.
    PF01292. Ni_hydr_CYTB. 1 hit.
    [Graphical view]
    PRINTSiPR00161. NIHGNASECYTB.
    SUPFAMiSSF81342. SSF81342. 1 hit.
    TIGRFAMsiTIGR02125. CytB-hydogenase. 1 hit.
    PROSITEiPS00882. NI_HGENASE_CYTB_1. 1 hit.
    PS00883. NI_HGENASE_CYTB_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P0AAM1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQQKSDNVVS HYVFEAPVRI WHWLTVLCMA VLMVTGYFIG KPLPSVSGEA    50
    TYLFYMGYIR LIHFSAGMVF TVVLLMRIYW AFVGNRYSRE LFIVPVWRKS 100
    WWQGVWYEIR WYLFLAKRPS ADIGHNPIAQ AAMFGYFLMS VFMIITGFAL 150
    YSEHSQYAIF APFRYVVEFF YWTGGNSMDI HSWHRLGMWL IGAFVIGHVY 200
    MALREDIMSD DTVISTMVNG YRSHKFGKIS NKERS 235
    Length:235
    Mass (Da):27,597
    Last modified:October 11, 2005 - v1
    Checksum:i98048DC800AB02C7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M34825 Genomic DNA. Translation: AAA23999.1.
    U00096 Genomic DNA. Translation: AAC74059.1.
    AP009048 Genomic DNA. Translation: BAA35739.1.
    PIRiJV0074. BVECYC.
    RefSeqiNP_415493.1. NC_000913.3.
    YP_489245.1. NC_007779.1.

    Genome annotation databases

    EnsemblBacteriaiAAC74059; AAC74059; b0974.
    BAA35739; BAA35739; BAA35739.
    GeneIDi12931050.
    945581.
    KEGGiecj:Y75_p0945.
    eco:b0974.
    PATRICi32117169. VBIEscCol129921_1008.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M34825 Genomic DNA. Translation: AAA23999.1 .
    U00096 Genomic DNA. Translation: AAC74059.1 .
    AP009048 Genomic DNA. Translation: BAA35739.1 .
    PIRi JV0074. BVECYC.
    RefSeqi NP_415493.1. NC_000913.3.
    YP_489245.1. NC_007779.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4GD3 X-ray 3.30 A/B 1-235 [» ]
    ProteinModelPortali P0AAM1.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    DIPi DIP-35859N.
    IntActi P0AAM1. 1 interaction.
    STRINGi 511145.b0974.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC74059 ; AAC74059 ; b0974 .
    BAA35739 ; BAA35739 ; BAA35739 .
    GeneIDi 12931050.
    945581.
    KEGGi ecj:Y75_p0945.
    eco:b0974.
    PATRICi 32117169. VBIEscCol129921_1008.

    Organism-specific databases

    EchoBASEi EB0465.
    EcoGenei EG10470. hyaC.

    Phylogenomic databases

    eggNOGi COG1969.
    HOGENOMi HOG000291339.
    KOi K03620.
    OMAi YWALVGN.
    OrthoDBi EOG6B8XHX.
    PhylomeDBi P0AAM1.

    Enzyme and pathway databases

    BioCyci EcoCyc:HYAC-MONOMER.
    ECOL316407:JW0956-MONOMER.
    MetaCyc:HYAC-MONOMER.

    Miscellaneous databases

    PROi P0AAM1.

    Gene expression databases

    Genevestigatori P0AAM1.

    Family and domain databases

    InterProi IPR011577. Cyt_b561_bac/Ni-Hgenase.
    IPR016174. Di-haem_cyt_TM.
    IPR000516. Ni-dep_Hydgase_cyt-B.
    [Graphical view ]
    Pfami PF00033. Cytochrom_B_N. 1 hit.
    PF01292. Ni_hydr_CYTB. 1 hit.
    [Graphical view ]
    PRINTSi PR00161. NIHGNASECYTB.
    SUPFAMi SSF81342. SSF81342. 1 hit.
    TIGRFAMsi TIGR02125. CytB-hydogenase. 1 hit.
    PROSITEi PS00882. NI_HGENASE_CYTB_1. 1 hit.
    PS00883. NI_HGENASE_CYTB_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning and sequencing of a putative Escherichia coli [NiFe] hydrogenase-1 operon containing six open reading frames."
      Menon N.K., Robbins J., Peck H.D. Jr., Chatelus C.Y., Choi E.-S., Przybyla A.E.
      J. Bacteriol. 172:1969-1977(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / MG1655 / ATCC 47076.
    4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
      Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
      Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
    5. "Global topology analysis of the Escherichia coli inner membrane proteome."
      Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
      Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
      Strain: K12 / MG1655 / ATCC 47076.

    Entry informationi

    Entry nameiCYBH_ECOLI
    AccessioniPrimary (citable) accession number: P0AAM1
    Secondary accession number(s): P19929
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 11, 2005
    Last sequence update: October 11, 2005
    Last modified: October 1, 2014
    This is version 75 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. Escherichia coli
      Escherichia coli (strain K12): entries and cross-references to EcoGene
    2. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3