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Protein

Electron transport protein HydN

Gene

hydN

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Electron transport from formate to hydrogen.1 Publication

Cofactori

[4Fe-4S] clusterBy similarityNote: Binds 4 [4Fe-4S] clusters.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi12 – 121Iron-sulfur 1 (4Fe-4S)By similarity
Metal bindingi15 – 151Iron-sulfur 1 (4Fe-4S)By similarity
Metal bindingi18 – 181Iron-sulfur 1 (4Fe-4S)By similarity
Metal bindingi22 – 221Iron-sulfur 2 (4Fe-4S)By similarity
Metal bindingi58 – 581Iron-sulfur 3 (4Fe-4S)By similarity
Metal bindingi61 – 611Iron-sulfur 3 (4Fe-4S)By similarity
Metal bindingi66 – 661Iron-sulfur 3 (4Fe-4S)By similarity
Metal bindingi70 – 701Iron-sulfur 4 (4Fe-4S)By similarity
Metal bindingi89 – 891Iron-sulfur 4 (4Fe-4S)By similarity
Metal bindingi92 – 921Iron-sulfur 4 (4Fe-4S)By similarity
Metal bindingi95 – 951Iron-sulfur 4 (4Fe-4S)By similarity
Metal bindingi99 – 991Iron-sulfur 3 (4Fe-4S)By similarity
Metal bindingi131 – 1311Iron-sulfur 2 (4Fe-4S)By similarity
Metal bindingi134 – 1341Iron-sulfur 2 (4Fe-4S)By similarity
Metal bindingi143 – 1431Iron-sulfur 2 (4Fe-4S)By similarity
Metal bindingi147 – 1471Iron-sulfur 1 (4Fe-4S)By similarity

GO - Molecular functioni

  • 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
  • electron carrier activity Source: EcoCyc
  • metal ion binding Source: UniProtKB-KW
  • oxidoreductase activity Source: GO_Central
Complete GO annotation...

Keywords - Biological processi

Electron transport, Transport

Keywords - Ligandi

4Fe-4S, Iron, Iron-sulfur, Metal-binding

Enzyme and pathway databases

BioCyciEcoCyc:EG11552-MONOMER.
ECOL316407:JW2683-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Electron transport protein HydN
Gene namesi
Name:hydN
Ordered Locus Names:b2713, JW2683
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11552. hydN.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 175175Electron transport protein HydNPRO_0000159269Add
BLAST

Proteomic databases

PaxDbiP0AAK4.

Interactioni

Protein-protein interaction databases

BioGridi4259425. 21 interactions.
IntActiP0AAK4. 13 interactions.
STRINGi511145.b2713.

Structurei

3D structure databases

ProteinModelPortaliP0AAK4.
SMRiP0AAK4. Positions 1-150.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 32314Fe-4S ferredoxin-type 1PROSITE-ProRule annotationAdd
BLAST
Domaini48 – 79324Fe-4S ferredoxin-type 2PROSITE-ProRule annotationAdd
BLAST
Domaini80 – 109304Fe-4S ferredoxin-type 3PROSITE-ProRule annotationAdd
BLAST
Domaini124 – 157344Fe-4S ferredoxin-type 4PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 4 4Fe-4S ferredoxin-type domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG4108RC0. Bacteria.
COG1142. LUCA.
HOGENOMiHOG000163385.
InParanoidiP0AAK4.
KOiK05796.
OMAiACVMAHS.
OrthoDBiEOG6XSZQF.
PhylomeDBiP0AAK4.

Family and domain databases

InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
[Graphical view]
PfamiPF13247. Fer4_11. 1 hit.
PF12798. Fer4_3. 1 hit.
PF12800. Fer4_4. 1 hit.
[Graphical view]
PROSITEiPS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AAK4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNRFIIADAS KCIGCRTCEV ACVVSHQENQ DCASLTPETF LPRIHVIKGV
60 70 80 90 100
NISTATVCRQ CEDAPCANVC PNGAISRDKG FVHVMQERCI GCKTCVVACP
110 120 130 140 150
YGAMEVVVRP VIRNSGAGLN VRADKAEANK CDLCNHREDG PACMAACPTH
160 170
ALICVDRNKL EQLSAEKRRR TALMF
Length:175
Mass (Da):19,026
Last modified:October 11, 2005 - v1
Checksum:iCB2A1C52BF6A558E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D14422 Genomic DNA. Translation: BAA03314.1.
U29579 Genomic DNA. Translation: AAA69223.1.
U00096 Genomic DNA. Translation: AAC75755.1.
AP009048 Genomic DNA. Translation: BAE76790.1.
PIRiE65051.
RefSeqiNP_417193.1. NC_000913.3.
WP_001078777.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75755; AAC75755; b2713.
BAE76790; BAE76790; BAE76790.
GeneIDi947190.
KEGGiecj:JW2683.
eco:b2713.
PATRICi32120824. VBIEscCol129921_2804.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D14422 Genomic DNA. Translation: BAA03314.1.
U29579 Genomic DNA. Translation: AAA69223.1.
U00096 Genomic DNA. Translation: AAC75755.1.
AP009048 Genomic DNA. Translation: BAE76790.1.
PIRiE65051.
RefSeqiNP_417193.1. NC_000913.3.
WP_001078777.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AAK4.
SMRiP0AAK4. Positions 1-150.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259425. 21 interactions.
IntActiP0AAK4. 13 interactions.
STRINGi511145.b2713.

Proteomic databases

PaxDbiP0AAK4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75755; AAC75755; b2713.
BAE76790; BAE76790; BAE76790.
GeneIDi947190.
KEGGiecj:JW2683.
eco:b2713.
PATRICi32120824. VBIEscCol129921_2804.

Organism-specific databases

EchoBASEiEB1513.
EcoGeneiEG11552. hydN.

Phylogenomic databases

eggNOGiENOG4108RC0. Bacteria.
COG1142. LUCA.
HOGENOMiHOG000163385.
InParanoidiP0AAK4.
KOiK05796.
OMAiACVMAHS.
OrthoDBiEOG6XSZQF.
PhylomeDBiP0AAK4.

Enzyme and pathway databases

BioCyciEcoCyc:EG11552-MONOMER.
ECOL316407:JW2683-MONOMER.

Miscellaneous databases

PROiP0AAK4.

Family and domain databases

InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
[Graphical view]
PfamiPF13247. Fer4_11. 1 hit.
PF12798. Fer4_3. 1 hit.
PF12800. Fer4_4. 1 hit.
[Graphical view]
PROSITEiPS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 4 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Ikebukuro K., Nishio M., Yano K., Tomiyama M., Tamiya E., Karube I.
    Submitted (FEB-1993) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "Analysis of the hydA locus of Escherichia coli: two genes (hydN and hypF) involved in formate and hydrogen metabolism."
    Maier T., Binder U., Boeck A.
    Arch. Microbiol. 165:333-341(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.

Entry informationi

Entry nameiHYDN_ECOLI
AccessioniPrimary (citable) accession number: P0AAK4
Secondary accession number(s): P30132, Q2MAB6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2005
Last sequence update: October 11, 2005
Last modified: June 8, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.