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Protein

Probable anaerobic dimethyl sulfoxide reductase chain YnfG

Gene

ynfG

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

Cofactori

[4Fe-4S] clusterBy similarityNote: Binds 4 [4Fe-4S] clusters.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi14 – 141Iron-sulfur 1 (4Fe-4S)By similarity
Metal bindingi17 – 171Iron-sulfur 1 (4Fe-4S)By similarity
Metal bindingi20 – 201Iron-sulfur 1 (4Fe-4S)By similarity
Metal bindingi24 – 241Iron-sulfur 2 (4Fe-4S)By similarity
Metal bindingi67 – 671Iron-sulfur 3 (4Fe-4S)By similarity
Metal bindingi70 – 701Iron-sulfur 3 (4Fe-4S)By similarity
Metal bindingi75 – 751Iron-sulfur 3 (4Fe-4S)By similarity
Metal bindingi79 – 791Iron-sulfur 4 (4Fe-4S)By similarity
Metal bindingi99 – 991Iron-sulfur 4 (4Fe-4S)By similarity
Metal bindingi102 – 1021Iron-sulfur 4 (4Fe-4S)By similarity
Metal bindingi105 – 1051Iron-sulfur 4 (4Fe-4S)By similarity
Metal bindingi109 – 1091Iron-sulfur 3 (4Fe-4S)By similarity
Metal bindingi126 – 1261Iron-sulfur 2 (4Fe-4S)By similarity
Metal bindingi129 – 1291Iron-sulfur 2 (4Fe-4S)By similarity
Metal bindingi141 – 1411Iron-sulfur 2 (4Fe-4S)By similarity
Metal bindingi145 – 1451Iron-sulfur 1 (4Fe-4S)By similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Electron transport, Transport

Keywords - Ligandi

4Fe-4S, Iron, Iron-sulfur, Metal-binding

Enzyme and pathway databases

BioCyciEcoCyc:G6847-MONOMER.
ECOL316407:JW1581-MONOMER.
MetaCyc:G6847-MONOMER.

Protein family/group databases

TCDBi5.A.3.3.1. the prokaryotic molybdopterin-containing oxidoreductase (pmo) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable anaerobic dimethyl sulfoxide reductase chain YnfG
Alternative name(s):
DMSO reductase iron-sulfur subunit YnfG
Gene namesi
Name:ynfG
Ordered Locus Names:b1589, JW1581
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13845. ynfG.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 205204Probable anaerobic dimethyl sulfoxide reductase chain YnfGPRO_0000159244Add
BLAST

Proteomic databases

PaxDbiP0AAJ1.

Interactioni

Subunit structurei

The complex consists of three subunits: YnfF, the reductase; YnfG, an electron transfer protein, and YnfH, a membrane anchor protein.Curated

Protein-protein interaction databases

BioGridi4263480. 4 interactions.
DIPiDIP-48224N.
STRINGi511145.b1589.

Structurei

3D structure databases

ProteinModelPortaliP0AAJ1.
SMRiP0AAJ1. Positions 4-194.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini5 – 33294Fe-4S ferredoxin-type 1PROSITE-ProRule annotationAdd
BLAST
Domaini59 – 89314Fe-4S ferredoxin-type 2PROSITE-ProRule annotationAdd
BLAST
Domaini90 – 119304Fe-4S ferredoxin-type 3PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 3 4Fe-4S ferredoxin-type domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG4105QAX. Bacteria.
COG0437. LUCA.
HOGENOMiHOG000163387.
InParanoidiP0AAJ1.
KOiK07311.
OMAiPGRARIF.
OrthoDBiEOG6JTC8Q.
PhylomeDBiP0AAJ1.

Family and domain databases

InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
IPR014297. DMSO_DmsB.
[Graphical view]
PfamiPF13247. Fer4_11. 1 hit.
PF12800. Fer4_4. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02951. DMSO_dmsB. 1 hit.
PROSITEiPS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0AAJ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTQYGFFID SSRCTGCKTC ELACKDFKDL GPEVSFRRIY EYAGGDWQED
60 70 80 90 100
NGVWHQNVFA YYLSISCNHC DDPACTKVCP SGAMHKREDG FVVVDEDVCI
110 120 130 140 150
GCRYCHMACP YGAPQYNAEK GHMTKCDGCY SRVAEGKQPI CVESCPLRAL
160 170 180 190 200
EFGPIEELRQ KHGTLAAVAP LPRAHFTKPN IVIKPNANSR PTGDTTGYLA

NPEEV
Length:205
Mass (Da):22,752
Last modified:January 23, 2007 - v2
Checksum:iB3B899744005D51C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74661.1.
AP009048 Genomic DNA. Translation: BAA15313.1.
PIRiG64914.
RefSeqiNP_416106.1. NC_000913.3.
WP_000213028.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74661; AAC74661; b1589.
BAA15313; BAA15313; BAA15313.
GeneIDi945638.
KEGGiecj:JW1581.
eco:b1589.
PATRICi32118480. VBIEscCol129921_1660.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74661.1.
AP009048 Genomic DNA. Translation: BAA15313.1.
PIRiG64914.
RefSeqiNP_416106.1. NC_000913.3.
WP_000213028.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AAJ1.
SMRiP0AAJ1. Positions 4-194.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263480. 4 interactions.
DIPiDIP-48224N.
STRINGi511145.b1589.

Protein family/group databases

TCDBi5.A.3.3.1. the prokaryotic molybdopterin-containing oxidoreductase (pmo) family.

Proteomic databases

PaxDbiP0AAJ1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74661; AAC74661; b1589.
BAA15313; BAA15313; BAA15313.
GeneIDi945638.
KEGGiecj:JW1581.
eco:b1589.
PATRICi32118480. VBIEscCol129921_1660.

Organism-specific databases

EchoBASEiEB3606.
EcoGeneiEG13845. ynfG.

Phylogenomic databases

eggNOGiENOG4105QAX. Bacteria.
COG0437. LUCA.
HOGENOMiHOG000163387.
InParanoidiP0AAJ1.
KOiK07311.
OMAiPGRARIF.
OrthoDBiEOG6JTC8Q.
PhylomeDBiP0AAJ1.

Enzyme and pathway databases

BioCyciEcoCyc:G6847-MONOMER.
ECOL316407:JW1581-MONOMER.
MetaCyc:G6847-MONOMER.

Miscellaneous databases

PROiP0AAJ1.

Family and domain databases

InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
IPR014297. DMSO_DmsB.
[Graphical view]
PfamiPF13247. Fer4_11. 1 hit.
PF12800. Fer4_4. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02951. DMSO_dmsB. 1 hit.
PROSITEiPS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiYNFG_ECOLI
AccessioniPrimary (citable) accession number: P0AAJ1
Secondary accession number(s): P77313
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2005
Last sequence update: January 23, 2007
Last modified: June 8, 2016
This is version 85 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.