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P0AAG3

- GLTL_ECOLI

UniProt

P0AAG3 - GLTL_ECOLI

Protein

Glutamate/aspartate transport ATP-binding protein GltL

Gene

gltL

Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 1 (11 Oct 2005)
      Previous versions | rss
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    Functioni

    Part of the binding-protein-dependent transport system for glutamate and aspartate. Probably responsible for energy coupling to the transport system.

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi34 – 418ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATPase activity Source: InterPro
    2. ATP binding Source: UniProtKB-KW

    GO - Biological processi

    1. amino acid transport Source: UniProtKB-KW

    Keywords - Biological processi

    Amino-acid transport, Transport

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciEcoCyc:GLTL-MONOMER.
    ECOL316407:JW0647-MONOMER.
    MetaCyc:GLTL-MONOMER.

    Protein family/group databases

    TCDBi3.A.1.3.4. the atp-binding cassette (abc) superfamily.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamate/aspartate transport ATP-binding protein GltL
    Gene namesi
    Name:gltL
    Ordered Locus Names:b0652, JW0647
    OrganismiEscherichia coli (strain K12)
    Taxonomic identifieri83333 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

    Organism-specific databases

    EcoGeneiEG12663. gltL.

    Subcellular locationi

    GO - Cellular componenti

    1. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 241241Glutamate/aspartate transport ATP-binding protein GltLPRO_0000092335Add
    BLAST

    Proteomic databases

    PaxDbiP0AAG3.

    Expressioni

    Gene expression databases

    GenevestigatoriP0AAG3.

    Interactioni

    Protein-protein interaction databases

    DIPiDIP-48246N.
    IntActiP0AAG3. 6 interactions.
    MINTiMINT-1307893.
    STRINGi511145.b0652.

    Structurei

    3D structure databases

    ProteinModelPortaliP0AAG3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini2 – 236235ABC transporterPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the ABC transporter superfamily.Curated
    Contains 1 ABC transporter domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG1126.
    KOiK10004.
    OMAiARALTMD.
    OrthoDBiEOG6T7N3V.
    PhylomeDBiP0AAG3.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    InterProiIPR003593. AAA+_ATPase.
    IPR003439. ABC_transporter-like.
    IPR017871. ABC_transporter_CS.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PfamiPF00005. ABC_tran. 1 hit.
    [Graphical view]
    SMARTiSM00382. AAA. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
    PS50893. ABC_TRANSPORTER_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P0AAG3-1 [UniParc]FASTAAdd to Basket

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    MITLKNVSKW YGHFQVLTDC STEVKKGEVV VVCGPSGSGK STLIKTVNGL    50
    EPVQQGEITV DGIVVNDKKT DLAKLRSRVG MVFQHFELFP HLSIIENLTL 100
    AQVKVLKRDK APAREKALKL LERVGLSAHA NKFPAQLSGG QQQRVAIARA 150
    LCMDPIAMLF DEPTSALDPE MINEVLDVMV ELANEGMTMM VVTHEMGFAR 200
    KVANRVIFMD EGKIVEDSPK DAFFDDPKSD RAKDFLAKIL H 241
    Length:241
    Mass (Da):26,661
    Last modified:October 11, 2005 - v1
    Checksum:i7643584D63FC424D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U10981 Genomic DNA. Translation: AAA60982.1.
    U82598 Genomic DNA. Translation: AAB40853.1.
    U00096 Genomic DNA. Translation: AAC73753.1.
    AP009048 Genomic DNA. Translation: BAA35304.1.
    PIRiB64800.
    RefSeqiNP_415185.1. NC_000913.3.
    YP_488943.1. NC_007779.1.

    Genome annotation databases

    EnsemblBacteriaiAAC73753; AAC73753; b0652.
    BAA35304; BAA35304; BAA35304.
    GeneIDi12930917.
    945254.
    KEGGiecj:Y75_p0642.
    eco:b0652.
    PATRICi32116487. VBIEscCol129921_0683.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U10981 Genomic DNA. Translation: AAA60982.1 .
    U82598 Genomic DNA. Translation: AAB40853.1 .
    U00096 Genomic DNA. Translation: AAC73753.1 .
    AP009048 Genomic DNA. Translation: BAA35304.1 .
    PIRi B64800.
    RefSeqi NP_415185.1. NC_000913.3.
    YP_488943.1. NC_007779.1.

    3D structure databases

    ProteinModelPortali P0AAG3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    DIPi DIP-48246N.
    IntActi P0AAG3. 6 interactions.
    MINTi MINT-1307893.
    STRINGi 511145.b0652.

    Protein family/group databases

    TCDBi 3.A.1.3.4. the atp-binding cassette (abc) superfamily.

    Proteomic databases

    PaxDbi P0AAG3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC73753 ; AAC73753 ; b0652 .
    BAA35304 ; BAA35304 ; BAA35304 .
    GeneIDi 12930917.
    945254.
    KEGGi ecj:Y75_p0642.
    eco:b0652.
    PATRICi 32116487. VBIEscCol129921_0683.

    Organism-specific databases

    EchoBASEi EB2529.
    EcoGenei EG12663. gltL.

    Phylogenomic databases

    eggNOGi COG1126.
    KOi K10004.
    OMAi ARALTMD.
    OrthoDBi EOG6T7N3V.
    PhylomeDBi P0AAG3.

    Enzyme and pathway databases

    BioCyci EcoCyc:GLTL-MONOMER.
    ECOL316407:JW0647-MONOMER.
    MetaCyc:GLTL-MONOMER.

    Miscellaneous databases

    PROi P0AAG3.

    Gene expression databases

    Genevestigatori P0AAG3.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    InterProi IPR003593. AAA+_ATPase.
    IPR003439. ABC_transporter-like.
    IPR017871. ABC_transporter_CS.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    Pfami PF00005. ABC_tran. 1 hit.
    [Graphical view ]
    SMARTi SM00382. AAA. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    PROSITEi PS00211. ABC_TRANSPORTER_1. 1 hit.
    PS50893. ABC_TRANSPORTER_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and characterisation of three genes of a glutamate-aspartate binding protein-dependent transport system of Escherichia coli K12."
      Lum D., Wallace B.J.
      Submitted (JUN-1994) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: K12 / BK9MDG.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
    3. "Sequence of minutes 4-25 of Escherichia coli."
      Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M., Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D., Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.
      Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / MG1655 / ATCC 47076.
    4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / MG1655 / ATCC 47076.
    5. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
      Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
      Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

    Entry informationi

    Entry nameiGLTL_ECOLI
    AccessioniPrimary (citable) accession number: P0AAG3
    Secondary accession number(s): P41076
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 11, 2005
    Last sequence update: October 11, 2005
    Last modified: October 1, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Escherichia coli
      Escherichia coli (strain K12): entries and cross-references to EcoGene
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3