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Protein

Dipeptide transport ATP-binding protein DppD

Gene

dppD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Part of the binding-protein-dependent transport system for dipeptides. Probably responsible for energy coupling to the transport system.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi40 – 478ATPPROSITE-ProRule annotation

GO - Molecular functioni

  • ATPase activity Source: InterPro
  • ATP binding Source: UniProtKB-KW
  • heme transporter activity Source: EcoliWiki

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Peptide transport, Protein transport, Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciEcoCyc:DPPD-MONOMER.
ECOL316407:JW3510-MONOMER.
MetaCyc:DPPD-MONOMER.
RETL1328306-WGS:GSTH-2070-MONOMER.
RETL1328306-WGS:GSTH-751-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Dipeptide transport ATP-binding protein DppD
Gene namesi
Name:dppD
Ordered Locus Names:b3541, JW3510
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12627. dppD.

Subcellular locationi

GO - Cellular componenti

  • ATP-binding cassette (ABC) transporter complex Source: EcoCyc
  • cytoplasm Source: EcoCyc
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 327327Dipeptide transport ATP-binding protein DppDPRO_0000092313Add
BLAST

Proteomic databases

EPDiP0AAG0.
PaxDbiP0AAG0.
PRIDEiP0AAG0.

Interactioni

Protein-protein interaction databases

BioGridi4262534. 244 interactions.
DIPiDIP-47940N.
IntActiP0AAG0. 2 interactions.
MINTiMINT-1258246.
STRINGi511145.b3541.

Structurei

3D structure databases

ProteinModelPortaliP0AAG0.
SMRiP0AAG0. Positions 3-316.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 254251ABC transporterPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the ABC transporter superfamily.Curated
Contains 1 ABC transporter domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105C3U. Bacteria.
COG0444. LUCA.
InParanoidiP0AAG0.
KOiK12371.
OMAiQRKENMA.
PhylomeDBiP0AAG0.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR013563. Oligopep_ABC_C.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00005. ABC_tran. 1 hit.
PF08352. oligo_HPY. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR01727. oligo_HPY. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AAG0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALLNVDKLS VHFGDESAPF RAVDRISYSV KQGEVVGIVG ESGSGKSVSS
60 70 80 90 100
LAIMGLIDYP GRVMAEKLEF NGQDLQRISE KERRNLVGAE VAMIFQDPMT
110 120 130 140 150
SLNPCYTVGF QIMEAIKVHQ GGNKSTRRQR AIDLLNQVGI PDPASRLDVY
160 170 180 190 200
PHQLSGGMSQ RVMIAMAIAC RPKLLIADEP TTALDVTIQA QIIELLLELQ
210 220 230 240 250
QKENMALVLI THDLALVAEA AHKIIVMYAG QVVETGDAHA IFHAPRHPYT
260 270 280 290 300
QALLRALPEF AQDKERLASL PGVVPGKYDR PNGCLLNPRC PYATDRCRAE
310 320
EPALNMLADG RQSKCHYPLD DAGRPTL
Length:327
Mass (Da):35,844
Last modified:October 11, 2005 - v1
Checksum:i1CBFD72388EE0569
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L08399 Genomic DNA. Translation: AAA23705.1.
U00039 Genomic DNA. Translation: AAB18519.1.
U00096 Genomic DNA. Translation: AAC76566.1.
AP009048 Genomic DNA. Translation: BAE77753.1.
PIRiS61404.
RefSeqiNP_417998.1. NC_000913.3.
WP_001196486.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76566; AAC76566; b3541.
BAE77753; BAE77753; BAE77753.
GeneIDi948065.
KEGGiecj:JW3510.
eco:b3541.
PATRICi32122550. VBIEscCol129921_3653.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L08399 Genomic DNA. Translation: AAA23705.1.
U00039 Genomic DNA. Translation: AAB18519.1.
U00096 Genomic DNA. Translation: AAC76566.1.
AP009048 Genomic DNA. Translation: BAE77753.1.
PIRiS61404.
RefSeqiNP_417998.1. NC_000913.3.
WP_001196486.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AAG0.
SMRiP0AAG0. Positions 3-316.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262534. 244 interactions.
DIPiDIP-47940N.
IntActiP0AAG0. 2 interactions.
MINTiMINT-1258246.
STRINGi511145.b3541.

Proteomic databases

EPDiP0AAG0.
PaxDbiP0AAG0.
PRIDEiP0AAG0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76566; AAC76566; b3541.
BAE77753; BAE77753; BAE77753.
GeneIDi948065.
KEGGiecj:JW3510.
eco:b3541.
PATRICi32122550. VBIEscCol129921_3653.

Organism-specific databases

EchoBASEiEB2511.
EcoGeneiEG12627. dppD.

Phylogenomic databases

eggNOGiENOG4105C3U. Bacteria.
COG0444. LUCA.
InParanoidiP0AAG0.
KOiK12371.
OMAiQRKENMA.
PhylomeDBiP0AAG0.

Enzyme and pathway databases

BioCyciEcoCyc:DPPD-MONOMER.
ECOL316407:JW3510-MONOMER.
MetaCyc:DPPD-MONOMER.
RETL1328306-WGS:GSTH-2070-MONOMER.
RETL1328306-WGS:GSTH-751-MONOMER.

Miscellaneous databases

PROiP0AAG0.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR013563. Oligopep_ABC_C.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00005. ABC_tran. 1 hit.
PF08352. oligo_HPY. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR01727. oligo_HPY. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDPPD_ECOLI
AccessioniPrimary (citable) accession number: P0AAG0
Secondary accession number(s): P37314, Q2M7K3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2005
Last sequence update: October 11, 2005
Last modified: September 7, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.