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Protein

Arginine transport ATP-binding protein ArtP

Gene

artP

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Part of the ABC transporter complex ArtPIQMJ involved in arginine transport. Probably responsible for energy coupling to the transport system.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi35 – 42ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

  • L-arginine import across plasma membrane Source: EcoCyc

Keywordsi

Molecular functionHydrolase
Biological processAmino-acid transport, Transport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciEcoCyc:ARTP-MONOMER
MetaCyc:ARTP-MONOMER

Protein family/group databases

TCDBi3.A.1.3.3 the atp-binding cassette (abc) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine transport ATP-binding protein ArtP (EC:3.6.3.-)
Gene namesi
Name:artP
Ordered Locus Names:b0864, JW0848
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11624 artP

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000919391 – 242Arginine transport ATP-binding protein ArtPAdd BLAST242

Proteomic databases

EPDiP0AAF6
PaxDbiP0AAF6
PRIDEiP0AAF6

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (ArtP), two transmembrane proteins (ArtM and ArtQ) and two solute-binding proteins (ArtJ and ArtI).1 Publication

Protein-protein interaction databases

BioGridi426313311 interactors.
DIPiDIP-47917N
IntActiP0AAF6 12 interactors.
STRINGi316385.ECDH10B_0934

Structurei

3D structure databases

ProteinModelPortaliP0AAF6
SMRiP0AAF6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 241ABC transporterPROSITE-ProRule annotationAdd BLAST239

Sequence similaritiesi

Belongs to the ABC transporter superfamily.Curated

Phylogenomic databases

eggNOGiENOG4105E5Z Bacteria
COG4161 LUCA
InParanoidiP0AAF6
KOiK10000
OMAiALINCPK
PhylomeDBiP0AAF6

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR030679 ABC_ATPase_HisP-typ
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00005 ABC_tran, 1 hit
PIRSFiPIRSF039085 ABC_ATPase_HisP, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit

Sequencei

Sequence statusi: Complete.

P0AAF6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIQLNGINC FYGAHQALFD ITLDCPQGET LVLLGPSGAG KSSLLRVLNL
60 70 80 90 100
LEMPRSGTLN IAGNHFDFTK TPSDKAIRDL RRNVGMVFQQ YNLWPHLTVQ
110 120 130 140 150
QNLIEAPCRV LGLSKDQALA RAEKLLERLR LKPYSDRYPL HLSGGQQQRV
160 170 180 190 200
AIARALMMEP QVLLFDEPTA ALDPEITAQI VSIIRELAET NITQVIVTHE
210 220 230 240
VEVARKTASR VVYMENGHIV EQGDASCFTE PQTEAFKNYL SH
Length:242
Mass (Da):27,022
Last modified:October 11, 2005 - v1
Checksum:iD5B50062E523413A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti94 – 95WP → CA in CAA60101 (PubMed:8501075).Curated2
Sequence conflicti121R → S in CAA60101 (PubMed:8501075).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X86160 Genomic DNA Translation: CAA60101.1
U00096 Genomic DNA Translation: AAC73951.1
AP009048 Genomic DNA Translation: BAA35578.1
PIRiH64824
RefSeqiNP_415385.1, NC_000913.3
WP_000027205.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73951; AAC73951; b0864
BAA35578; BAA35578; BAA35578
GeneIDi945489
KEGGiecj:JW0848
eco:b0864
PATRICifig|1411691.4.peg.1413

Similar proteinsi

Entry informationi

Entry nameiARTP_ECOLI
AccessioniPrimary (citable) accession number: P0AAF6
Secondary accession number(s): P30858, P77355
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2005
Last sequence update: October 11, 2005
Last modified: March 28, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome