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Protein

Arginine transport ATP-binding protein ArtP

Gene

artP

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Part of the ABC transporter complex ArtPIQMJ involved in arginine transport. Probably responsible for energy coupling to the transport system.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi35 – 42ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

  • L-arginine import into cell Source: EcoCyc
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Amino-acid transport, Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciEcoCyc:ARTP-MONOMER.
ECOL316407:JW0848-MONOMER.
MetaCyc:ARTP-MONOMER.

Protein family/group databases

TCDBi3.A.1.3.3. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine transport ATP-binding protein ArtP (EC:3.6.3.-)
Gene namesi
Name:artP
Ordered Locus Names:b0864, JW0848
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11624. artP.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000919391 – 242Arginine transport ATP-binding protein ArtPAdd BLAST242

Proteomic databases

EPDiP0AAF6.
PaxDbiP0AAF6.
PRIDEiP0AAF6.

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (ArtP), two transmembrane proteins (ArtM and ArtQ) and two solute-binding proteins (ArtJ and ArtI).1 Publication

Protein-protein interaction databases

BioGridi4263133. 7 interactors.
DIPiDIP-47917N.
IntActiP0AAF6. 12 interactors.
MINTiMINT-1236053.
STRINGi511145.b0864.

Structurei

3D structure databases

ProteinModelPortaliP0AAF6.
SMRiP0AAF6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 241ABC transporterPROSITE-ProRule annotationAdd BLAST239

Sequence similaritiesi

Belongs to the ABC transporter superfamily.Curated
Contains 1 ABC transporter domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105E5Z. Bacteria.
COG4161. LUCA.
InParanoidiP0AAF6.
KOiK10000.
OMAiMAIHYLR.
PhylomeDBiP0AAF6.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR030679. ABC_ATPase_HisP-typ.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00005. ABC_tran. 1 hit.
[Graphical view]
PIRSFiPIRSF039085. ABC_ATPase_HisP. 1 hit.
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AAF6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIQLNGINC FYGAHQALFD ITLDCPQGET LVLLGPSGAG KSSLLRVLNL
60 70 80 90 100
LEMPRSGTLN IAGNHFDFTK TPSDKAIRDL RRNVGMVFQQ YNLWPHLTVQ
110 120 130 140 150
QNLIEAPCRV LGLSKDQALA RAEKLLERLR LKPYSDRYPL HLSGGQQQRV
160 170 180 190 200
AIARALMMEP QVLLFDEPTA ALDPEITAQI VSIIRELAET NITQVIVTHE
210 220 230 240
VEVARKTASR VVYMENGHIV EQGDASCFTE PQTEAFKNYL SH
Length:242
Mass (Da):27,022
Last modified:October 11, 2005 - v1
Checksum:iD5B50062E523413A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti94 – 95WP → CA in CAA60101 (PubMed:8501075).Curated2
Sequence conflicti121R → S in CAA60101 (PubMed:8501075).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X86160 Genomic DNA. Translation: CAA60101.1.
U00096 Genomic DNA. Translation: AAC73951.1.
AP009048 Genomic DNA. Translation: BAA35578.1.
PIRiH64824.
RefSeqiNP_415385.1. NC_000913.3.
WP_000027205.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73951; AAC73951; b0864.
BAA35578; BAA35578; BAA35578.
GeneIDi945489.
KEGGiecj:JW0848.
eco:b0864.
PATRICi32116935. VBIEscCol129921_0893.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X86160 Genomic DNA. Translation: CAA60101.1.
U00096 Genomic DNA. Translation: AAC73951.1.
AP009048 Genomic DNA. Translation: BAA35578.1.
PIRiH64824.
RefSeqiNP_415385.1. NC_000913.3.
WP_000027205.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AAF6.
SMRiP0AAF6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263133. 7 interactors.
DIPiDIP-47917N.
IntActiP0AAF6. 12 interactors.
MINTiMINT-1236053.
STRINGi511145.b0864.

Protein family/group databases

TCDBi3.A.1.3.3. the atp-binding cassette (abc) superfamily.

Proteomic databases

EPDiP0AAF6.
PaxDbiP0AAF6.
PRIDEiP0AAF6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73951; AAC73951; b0864.
BAA35578; BAA35578; BAA35578.
GeneIDi945489.
KEGGiecj:JW0848.
eco:b0864.
PATRICi32116935. VBIEscCol129921_0893.

Organism-specific databases

EchoBASEiEB1581.
EcoGeneiEG11624. artP.

Phylogenomic databases

eggNOGiENOG4105E5Z. Bacteria.
COG4161. LUCA.
InParanoidiP0AAF6.
KOiK10000.
OMAiMAIHYLR.
PhylomeDBiP0AAF6.

Enzyme and pathway databases

BioCyciEcoCyc:ARTP-MONOMER.
ECOL316407:JW0848-MONOMER.
MetaCyc:ARTP-MONOMER.

Miscellaneous databases

PROiP0AAF6.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR030679. ABC_ATPase_HisP-typ.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00005. ABC_tran. 1 hit.
[Graphical view]
PIRSFiPIRSF039085. ABC_ATPase_HisP. 1 hit.
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiARTP_ECOLI
AccessioniPrimary (citable) accession number: P0AAF6
Secondary accession number(s): P30858, P77355
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2005
Last sequence update: October 11, 2005
Last modified: November 2, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.