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P0AAE5 (ARCD_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative arginine/ornithine antiporter
Gene names
Name:ydgI
Ordered Locus Names:b1605, JW1597
OrganismEscherichia coli (strain K12) [Reference proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length460 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway By similarity.

Subcellular location

Cell inner membrane; Multi-pass membrane protein.

Sequence similarities

Belongs to the amino acid-polyamine-organocation (APC) superfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 460460Putative arginine/ornithine antiporter
PRO_0000054241

Regions

Topological domain1 – 44Cytoplasmic Potential
Transmembrane5 – 2521Helical; Potential
Topological domain26 – 3813Periplasmic Potential
Transmembrane39 – 5921Helical; Potential
Topological domain60 – 9233Cytoplasmic Potential
Transmembrane93 – 11321Helical; Potential
Topological domain114 – 12512Periplasmic Potential
Transmembrane126 – 14621Helical; Potential
Topological domain147 – 15711Cytoplasmic Potential
Transmembrane158 – 17821Helical; Potential
Topological domain179 – 20123Periplasmic Potential
Transmembrane202 – 22221Helical; Potential
Topological domain223 – 23513Cytoplasmic Potential
Transmembrane236 – 25621Helical; Potential
Topological domain257 – 28226Periplasmic Potential
Transmembrane283 – 30321Helical; Potential
Topological domain304 – 33128Cytoplasmic Potential
Transmembrane332 – 35221Helical; Potential
Topological domain353 – 3575Periplasmic Potential
Transmembrane358 – 37821Helical; Potential
Topological domain379 – 3846Cytoplasmic Potential
Transmembrane385 – 40521Helical; Potential
Transmembrane406 – 42621Helical; Potential
Topological domain427 – 43913Periplasmic Potential
Transmembrane440 – 46021Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P0AAE5 [UniParc].

Last modified October 11, 2005. Version 1.
Checksum: 4E0FE8E1861FA1B3

FASTA46049,501
        10         20         30         40         50         60 
MEKKLGLSAL TALVLSSMLG AGVFSLPQNM AAVASPAALL IGWGITGAGI LLLAFAMLIL 

        70         80         90        100        110        120 
TRIRPELDGG IFTYAREGFG ELIGFCSAWG YWLCAVIANV SYLVIVFSAL SFFTDTPELR 

       130        140        150        160        170        180 
LFGDGNTWQS IVGASALLWI VHFLILRGVQ TAASINLVAT LAKLLPLGLF VVLAMMMFKL 

       190        200        210        220        230        240 
DTFKLDFTGL ALGVPVWEQV KNTMLITLWV FIGVEGAVVV SARARNKRDV GKATLLAVLS 

       250        260        270        280        290        300 
ALGVYLLVTL LSLGVVARPE LAEIRNPSMA GLMVEMMGPW GEIIIAAGLI VSVCGAYLSW 

       310        320        330        340        350        360 
TIMAAEVPFL AATHKAFPRI FARQNAQAAP SASLWLTNIC VQICLVLIWL TGSDYNTLLT 

       370        380        390        400        410        420 
IASEMILVPY FLVGAFLLKI ATRPLHKAVG VGACIYGLWL LYASGPMHLL LSVVLYAPGL 

       430        440        450        460 
LVFLYARKTH THDNVLNRQE MVLIGMLLIA SVPATWMLVG 

« Hide

References

[1]"A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map."
Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T., Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T., Mizobuchi K., Mori H., Mori T., Motomura K. expand/collapse author list , Nakade S., Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y., Wada C., Yamamoto Y., Horiuchi T.
DNA Res. 3:363-377(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1462(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[3]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]"Global topology analysis of the Escherichia coli inner membrane proteome."
Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
Strain: K12 / MG1655 / ATCC 47076.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U00096 Genomic DNA. Translation: AAC74677.1.
AP009048 Genomic DNA. Translation: BAA15343.1.
PIRG64916.
RefSeqNP_416122.1. NC_000913.3.
YP_489868.1. NC_007779.1.

3D structure databases

ProteinModelPortalP0AAE5.
SMRP0AAE5. Positions 6-437.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-48049N.
IntActP0AAE5. 1 interaction.
STRING511145.b1605.

Protein family/group databases

TCDB2.A.3.2.8. the amino acid-polyamine-organocation (apc) family.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC74677; AAC74677; b1605.
BAA15343; BAA15343; BAA15343.
GeneID12930133.
945159.
KEGGecj:Y75_p1581.
eco:b1605.
PATRIC32118512. VBIEscCol129921_1676.

Organism-specific databases

EchoBASEEB3689.
EcoGeneEG13930. ydgI.

Phylogenomic databases

eggNOGCOG0531.
HOGENOMHOG000164505.
KOK03758.
OMAVHWLVLR.
OrthoDBEOG69GZN5.
PhylomeDBP0AAE5.

Enzyme and pathway databases

BioCycEcoCyc:ARCD-MONOMER.
ECOL316407:JW1597-MONOMER.

Gene expression databases

GenevestigatorP0AAE5.

Family and domain databases

InterProIPR002293. AA/rel_permease1.
IPR004754. Amino_acid_antiprt.
[Graphical view]
PANTHERPTHR11785. PTHR11785. 1 hit.
PfamPF13520. AA_permease_2. 1 hit.
[Graphical view]
PIRSFPIRSF006060. AA_transporter. 1 hit.
TIGRFAMsTIGR00905. 2A0302. 1 hit.
ProtoNetSearch...

Other

PROP0AAE5.

Entry information

Entry nameARCD_ECOLI
AccessionPrimary (citable) accession number: P0AAE5
Secondary accession number(s): P77429
Entry history
Integrated into UniProtKB/Swiss-Prot: October 11, 2005
Last sequence update: October 11, 2005
Last modified: May 14, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene