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P0AAE5

- ARCD_ECOLI

UniProt

P0AAE5 - ARCD_ECOLI

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Protein

Putative arginine/ornithine antiporter

Gene

ydgI

Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway.By similarity

GO - Molecular functioni

  1. amino acid transmembrane transporter activity Source: InterPro
  2. antiporter activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Amino-acid transport, Antiport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:ARCD-MONOMER.
ECOL316407:JW1597-MONOMER.

Protein family/group databases

TCDBi2.A.3.2.8. the amino acid-polyamine-organocation (apc) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative arginine/ornithine antiporter
Gene namesi
Name:ydgI
Ordered Locus Names:b1605, JW1597
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

Organism-specific databases

EcoGeneiEG13930. ydgI.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 44CytoplasmicSequence Analysis
Transmembranei5 – 2521HelicalSequence AnalysisAdd
BLAST
Topological domaini26 – 3813PeriplasmicSequence AnalysisAdd
BLAST
Transmembranei39 – 5921HelicalSequence AnalysisAdd
BLAST
Topological domaini60 – 9233CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei93 – 11321HelicalSequence AnalysisAdd
BLAST
Topological domaini114 – 12512PeriplasmicSequence AnalysisAdd
BLAST
Transmembranei126 – 14621HelicalSequence AnalysisAdd
BLAST
Topological domaini147 – 15711CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei158 – 17821HelicalSequence AnalysisAdd
BLAST
Topological domaini179 – 20123PeriplasmicSequence AnalysisAdd
BLAST
Transmembranei202 – 22221HelicalSequence AnalysisAdd
BLAST
Topological domaini223 – 23513CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei236 – 25621HelicalSequence AnalysisAdd
BLAST
Topological domaini257 – 28226PeriplasmicSequence AnalysisAdd
BLAST
Transmembranei283 – 30321HelicalSequence AnalysisAdd
BLAST
Topological domaini304 – 33128CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei332 – 35221HelicalSequence AnalysisAdd
BLAST
Topological domaini353 – 3575PeriplasmicSequence Analysis
Transmembranei358 – 37821HelicalSequence AnalysisAdd
BLAST
Topological domaini379 – 3846CytoplasmicSequence Analysis
Transmembranei385 – 40521HelicalSequence AnalysisAdd
BLAST
Transmembranei406 – 42621HelicalSequence AnalysisAdd
BLAST
Topological domaini427 – 43913PeriplasmicSequence AnalysisAdd
BLAST
Transmembranei440 – 46021HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 460460Putative arginine/ornithine antiporterPRO_0000054241Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriP0AAE5.

Interactioni

Protein-protein interaction databases

DIPiDIP-48049N.
IntActiP0AAE5. 1 interaction.
STRINGi511145.b1605.

Structurei

3D structure databases

ProteinModelPortaliP0AAE5.
SMRiP0AAE5. Positions 2-434.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0531.
HOGENOMiHOG000164505.
InParanoidiP0AAE5.
KOiK03758.
OMAiVHWLVLR.
OrthoDBiEOG69GZN5.
PhylomeDBiP0AAE5.

Family and domain databases

InterProiIPR002293. AA/rel_permease1.
IPR004754. Amino_acid_antiprt.
[Graphical view]
PANTHERiPTHR11785. PTHR11785. 1 hit.
PfamiPF13520. AA_permease_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006060. AA_transporter. 1 hit.
TIGRFAMsiTIGR00905. 2A0302. 1 hit.

Sequencei

Sequence statusi: Complete.

P0AAE5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEKKLGLSAL TALVLSSMLG AGVFSLPQNM AAVASPAALL IGWGITGAGI
60 70 80 90 100
LLLAFAMLIL TRIRPELDGG IFTYAREGFG ELIGFCSAWG YWLCAVIANV
110 120 130 140 150
SYLVIVFSAL SFFTDTPELR LFGDGNTWQS IVGASALLWI VHFLILRGVQ
160 170 180 190 200
TAASINLVAT LAKLLPLGLF VVLAMMMFKL DTFKLDFTGL ALGVPVWEQV
210 220 230 240 250
KNTMLITLWV FIGVEGAVVV SARARNKRDV GKATLLAVLS ALGVYLLVTL
260 270 280 290 300
LSLGVVARPE LAEIRNPSMA GLMVEMMGPW GEIIIAAGLI VSVCGAYLSW
310 320 330 340 350
TIMAAEVPFL AATHKAFPRI FARQNAQAAP SASLWLTNIC VQICLVLIWL
360 370 380 390 400
TGSDYNTLLT IASEMILVPY FLVGAFLLKI ATRPLHKAVG VGACIYGLWL
410 420 430 440 450
LYASGPMHLL LSVVLYAPGL LVFLYARKTH THDNVLNRQE MVLIGMLLIA
460
SVPATWMLVG
Length:460
Mass (Da):49,501
Last modified:October 11, 2005 - v1
Checksum:i4E0FE8E1861FA1B3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74677.1.
AP009048 Genomic DNA. Translation: BAA15343.1.
PIRiG64916.
RefSeqiNP_416122.1. NC_000913.3.
YP_489868.1. NC_007779.1.

Genome annotation databases

EnsemblBacteriaiAAC74677; AAC74677; b1605.
BAA15343; BAA15343; BAA15343.
GeneIDi12930133.
945159.
KEGGiecj:Y75_p1581.
eco:b1605.
PATRICi32118512. VBIEscCol129921_1676.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74677.1 .
AP009048 Genomic DNA. Translation: BAA15343.1 .
PIRi G64916.
RefSeqi NP_416122.1. NC_000913.3.
YP_489868.1. NC_007779.1.

3D structure databases

ProteinModelPortali P0AAE5.
SMRi P0AAE5. Positions 2-434.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-48049N.
IntActi P0AAE5. 1 interaction.
STRINGi 511145.b1605.

Protein family/group databases

TCDBi 2.A.3.2.8. the amino acid-polyamine-organocation (apc) family.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC74677 ; AAC74677 ; b1605 .
BAA15343 ; BAA15343 ; BAA15343 .
GeneIDi 12930133.
945159.
KEGGi ecj:Y75_p1581.
eco:b1605.
PATRICi 32118512. VBIEscCol129921_1676.

Organism-specific databases

EchoBASEi EB3689.
EcoGenei EG13930. ydgI.

Phylogenomic databases

eggNOGi COG0531.
HOGENOMi HOG000164505.
InParanoidi P0AAE5.
KOi K03758.
OMAi VHWLVLR.
OrthoDBi EOG69GZN5.
PhylomeDBi P0AAE5.

Enzyme and pathway databases

BioCyci EcoCyc:ARCD-MONOMER.
ECOL316407:JW1597-MONOMER.

Miscellaneous databases

PROi P0AAE5.

Gene expression databases

Genevestigatori P0AAE5.

Family and domain databases

InterProi IPR002293. AA/rel_permease1.
IPR004754. Amino_acid_antiprt.
[Graphical view ]
PANTHERi PTHR11785. PTHR11785. 1 hit.
Pfami PF13520. AA_permease_2. 1 hit.
[Graphical view ]
PIRSFi PIRSF006060. AA_transporter. 1 hit.
TIGRFAMsi TIGR00905. 2A0302. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiARCD_ECOLI
AccessioniPrimary (citable) accession number: P0AAE5
Secondary accession number(s): P77429
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2005
Last sequence update: October 11, 2005
Last modified: October 29, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3