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P0AAE5

- ARCD_ECOLI

UniProt

P0AAE5 - ARCD_ECOLI

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Protein
Putative arginine/ornithine antiporter
Gene
ydgI, b1605, JW1597
Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway By similarity.

GO - Molecular functioni

  1. amino acid transmembrane transporter activity Source: InterPro
  2. antiporter activity Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Biological processi

    Amino-acid transport, Antiport, Transport

    Enzyme and pathway databases

    BioCyciEcoCyc:ARCD-MONOMER.
    ECOL316407:JW1597-MONOMER.

    Protein family/group databases

    TCDBi2.A.3.2.8. the amino acid-polyamine-organocation (apc) family.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative arginine/ornithine antiporter
    Gene namesi
    Name:ydgI
    Ordered Locus Names:b1605, JW1597
    OrganismiEscherichia coli (strain K12)
    Taxonomic identifieri83333 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

    Organism-specific databases

    EcoGeneiEG13930. ydgI.

    Subcellular locationi

    Topology

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 44Cytoplasmic Reviewed prediction
    Transmembranei5 – 2521Helical; Reviewed prediction
    Add
    BLAST
    Topological domaini26 – 3813Periplasmic Reviewed prediction
    Add
    BLAST
    Transmembranei39 – 5921Helical; Reviewed prediction
    Add
    BLAST
    Topological domaini60 – 9233Cytoplasmic Reviewed prediction
    Add
    BLAST
    Transmembranei93 – 11321Helical; Reviewed prediction
    Add
    BLAST
    Topological domaini114 – 12512Periplasmic Reviewed prediction
    Add
    BLAST
    Transmembranei126 – 14621Helical; Reviewed prediction
    Add
    BLAST
    Topological domaini147 – 15711Cytoplasmic Reviewed prediction
    Add
    BLAST
    Transmembranei158 – 17821Helical; Reviewed prediction
    Add
    BLAST
    Topological domaini179 – 20123Periplasmic Reviewed prediction
    Add
    BLAST
    Transmembranei202 – 22221Helical; Reviewed prediction
    Add
    BLAST
    Topological domaini223 – 23513Cytoplasmic Reviewed prediction
    Add
    BLAST
    Transmembranei236 – 25621Helical; Reviewed prediction
    Add
    BLAST
    Topological domaini257 – 28226Periplasmic Reviewed prediction
    Add
    BLAST
    Transmembranei283 – 30321Helical; Reviewed prediction
    Add
    BLAST
    Topological domaini304 – 33128Cytoplasmic Reviewed prediction
    Add
    BLAST
    Transmembranei332 – 35221Helical; Reviewed prediction
    Add
    BLAST
    Topological domaini353 – 3575Periplasmic Reviewed prediction
    Transmembranei358 – 37821Helical; Reviewed prediction
    Add
    BLAST
    Topological domaini379 – 3846Cytoplasmic Reviewed prediction
    Transmembranei385 – 40521Helical; Reviewed prediction
    Add
    BLAST
    Transmembranei406 – 42621Helical; Reviewed prediction
    Add
    BLAST
    Topological domaini427 – 43913Periplasmic Reviewed prediction
    Add
    BLAST
    Transmembranei440 – 46021Helical; Reviewed prediction
    Add
    BLAST

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell
    Complete GO annotation...

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 460460Putative arginine/ornithine antiporter
    PRO_0000054241Add
    BLAST

    Expressioni

    Gene expression databases

    GenevestigatoriP0AAE5.

    Interactioni

    Protein-protein interaction databases

    DIPiDIP-48049N.
    IntActiP0AAE5. 1 interaction.
    STRINGi511145.b1605.

    Structurei

    3D structure databases

    ProteinModelPortaliP0AAE5.
    SMRiP0AAE5. Positions 6-437.

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0531.
    HOGENOMiHOG000164505.
    KOiK03758.
    OMAiVHWLVLR.
    OrthoDBiEOG69GZN5.
    PhylomeDBiP0AAE5.

    Family and domain databases

    InterProiIPR002293. AA/rel_permease1.
    IPR004754. Amino_acid_antiprt.
    [Graphical view]
    PANTHERiPTHR11785. PTHR11785. 1 hit.
    PfamiPF13520. AA_permease_2. 1 hit.
    [Graphical view]
    PIRSFiPIRSF006060. AA_transporter. 1 hit.
    TIGRFAMsiTIGR00905. 2A0302. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P0AAE5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEKKLGLSAL TALVLSSMLG AGVFSLPQNM AAVASPAALL IGWGITGAGI    50
    LLLAFAMLIL TRIRPELDGG IFTYAREGFG ELIGFCSAWG YWLCAVIANV 100
    SYLVIVFSAL SFFTDTPELR LFGDGNTWQS IVGASALLWI VHFLILRGVQ 150
    TAASINLVAT LAKLLPLGLF VVLAMMMFKL DTFKLDFTGL ALGVPVWEQV 200
    KNTMLITLWV FIGVEGAVVV SARARNKRDV GKATLLAVLS ALGVYLLVTL 250
    LSLGVVARPE LAEIRNPSMA GLMVEMMGPW GEIIIAAGLI VSVCGAYLSW 300
    TIMAAEVPFL AATHKAFPRI FARQNAQAAP SASLWLTNIC VQICLVLIWL 350
    TGSDYNTLLT IASEMILVPY FLVGAFLLKI ATRPLHKAVG VGACIYGLWL 400
    LYASGPMHLL LSVVLYAPGL LVFLYARKTH THDNVLNRQE MVLIGMLLIA 450
    SVPATWMLVG 460
    Length:460
    Mass (Da):49,501
    Last modified:October 11, 2005 - v1
    Checksum:i4E0FE8E1861FA1B3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00096 Genomic DNA. Translation: AAC74677.1.
    AP009048 Genomic DNA. Translation: BAA15343.1.
    PIRiG64916.
    RefSeqiNP_416122.1. NC_000913.3.
    YP_489868.1. NC_007779.1.

    Genome annotation databases

    EnsemblBacteriaiAAC74677; AAC74677; b1605.
    BAA15343; BAA15343; BAA15343.
    GeneIDi12930133.
    945159.
    KEGGiecj:Y75_p1581.
    eco:b1605.
    PATRICi32118512. VBIEscCol129921_1676.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00096 Genomic DNA. Translation: AAC74677.1 .
    AP009048 Genomic DNA. Translation: BAA15343.1 .
    PIRi G64916.
    RefSeqi NP_416122.1. NC_000913.3.
    YP_489868.1. NC_007779.1.

    3D structure databases

    ProteinModelPortali P0AAE5.
    SMRi P0AAE5. Positions 6-437.
    ModBasei Search...

    Protein-protein interaction databases

    DIPi DIP-48049N.
    IntActi P0AAE5. 1 interaction.
    STRINGi 511145.b1605.

    Protein family/group databases

    TCDBi 2.A.3.2.8. the amino acid-polyamine-organocation (apc) family.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC74677 ; AAC74677 ; b1605 .
    BAA15343 ; BAA15343 ; BAA15343 .
    GeneIDi 12930133.
    945159.
    KEGGi ecj:Y75_p1581.
    eco:b1605.
    PATRICi 32118512. VBIEscCol129921_1676.

    Organism-specific databases

    EchoBASEi EB3689.
    EcoGenei EG13930. ydgI.

    Phylogenomic databases

    eggNOGi COG0531.
    HOGENOMi HOG000164505.
    KOi K03758.
    OMAi VHWLVLR.
    OrthoDBi EOG69GZN5.
    PhylomeDBi P0AAE5.

    Enzyme and pathway databases

    BioCyci EcoCyc:ARCD-MONOMER.
    ECOL316407:JW1597-MONOMER.

    Miscellaneous databases

    PROi P0AAE5.

    Gene expression databases

    Genevestigatori P0AAE5.

    Family and domain databases

    InterProi IPR002293. AA/rel_permease1.
    IPR004754. Amino_acid_antiprt.
    [Graphical view ]
    PANTHERi PTHR11785. PTHR11785. 1 hit.
    Pfami PF13520. AA_permease_2. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF006060. AA_transporter. 1 hit.
    TIGRFAMsi TIGR00905. 2A0302. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / MG1655 / ATCC 47076.
    3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
      Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
      Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
    4. "Global topology analysis of the Escherichia coli inner membrane proteome."
      Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
      Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
      Strain: K12 / MG1655 / ATCC 47076.

    Entry informationi

    Entry nameiARCD_ECOLI
    AccessioniPrimary (citable) accession number: P0AAE5
    Secondary accession number(s): P77429
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 11, 2005
    Last sequence update: October 11, 2005
    Last modified: May 14, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Escherichia coli
      Escherichia coli (strain K12): entries and cross-references to EcoGene
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

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