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Protein

Inner membrane protein YbhL

Gene

ybhL

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:G6403-MONOMER.
ECOL316407:JW0769-MONOMER.

Protein family/group databases

TCDBi1.A.14.2.2. the testis-enhanced gene transfer (tegt) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane protein YbhL
Gene namesi
Name:ybhL
Ordered Locus Names:b0786, JW0769
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13668. ybhL.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2323PeriplasmicSequence analysisAdd
BLAST
Transmembranei24 – 4421HelicalSequence analysisAdd
BLAST
Topological domaini45 – 5612CytoplasmicSequence analysisAdd
BLAST
Transmembranei57 – 7721HelicalSequence analysisAdd
BLAST
Topological domaini78 – 792PeriplasmicSequence analysis
Transmembranei80 – 10021HelicalSequence analysisAdd
BLAST
Topological domaini101 – 1022CytoplasmicSequence analysis
Transmembranei103 – 12321HelicalSequence analysisAdd
BLAST
Topological domaini124 – 13613PeriplasmicSequence analysisAdd
BLAST
Transmembranei137 – 15721HelicalSequence analysisAdd
BLAST
Topological domaini158 – 1636CytoplasmicSequence analysis
Transmembranei164 – 18421HelicalSequence analysisAdd
BLAST
Topological domaini185 – 20622PeriplasmicSequence analysisAdd
BLAST
Transmembranei207 – 22721HelicalSequence analysisAdd
BLAST
Topological domaini228 – 2347CytoplasmicSequence analysis

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 234234Inner membrane protein YbhLPRO_0000179100Add
BLAST

Proteomic databases

PaxDbiP0AAC4.
PRIDEiP0AAC4.

Interactioni

Protein-protein interaction databases

BioGridi4262178. 4 interactions.
STRINGi511145.b0786.

Structurei

3D structure databases

ProteinModelPortaliP0AAC4.
SMRiP0AAC4. Positions 19-232.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the BI1 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105HFZ. Bacteria.
COG0670. LUCA.
HOGENOMiHOG000060392.
InParanoidiP0AAC4.
KOiK06890.
OMAiLIIAQFG.
OrthoDBiEOG625K1S.
PhylomeDBiP0AAC4.

Family and domain databases

InterProiIPR006214. Bax_inhibitor_1-related.
[Graphical view]
PANTHERiPTHR23291. PTHR23291. 1 hit.

Sequencei

Sequence statusi: Complete.

P0AAC4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRFPRSDSI VQPRAGLQTY MAQVYGWMTV GLLLTAFVAW YAANSAAVME
60 70 80 90 100
LLFTNRVFLI GLIIAQLALV IVLSAMIQKL SAGVTTMLFM LYSALTGLTL
110 120 130 140 150
SSIFIVYTAA SIASTFVVTA GMFGAMSLYG YTTKRDLSGF GNMLFMALIG
160 170 180 190 200
IVLASLVNFW LKSEALMWAV TYIGVIVFVG LTAYDTQKLK NMGEQIDTRD
210 220 230
TSNLRKYSIL GALTLYLDFI NLFLMLLRIF GNRR
Length:234
Mass (Da):25,902
Last modified:September 13, 2005 - v1
Checksum:i7A59105563D5DFC8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC73873.1.
AP009048 Genomic DNA. Translation: BAA35444.1.
PIRiB64815.
RefSeqiNP_415307.1. NC_000913.3.
WP_000373624.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73873; AAC73873; b0786.
BAA35444; BAA35444; BAA35444.
GeneIDi945401.
KEGGiecj:JW0769.
eco:b0786.
PATRICi32116773. VBIEscCol129921_0812.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC73873.1.
AP009048 Genomic DNA. Translation: BAA35444.1.
PIRiB64815.
RefSeqiNP_415307.1. NC_000913.3.
WP_000373624.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AAC4.
SMRiP0AAC4. Positions 19-232.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262178. 4 interactions.
STRINGi511145.b0786.

Protein family/group databases

TCDBi1.A.14.2.2. the testis-enhanced gene transfer (tegt) family.

Proteomic databases

PaxDbiP0AAC4.
PRIDEiP0AAC4.

Protocols and materials databases

DNASUi945401.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73873; AAC73873; b0786.
BAA35444; BAA35444; BAA35444.
GeneIDi945401.
KEGGiecj:JW0769.
eco:b0786.
PATRICi32116773. VBIEscCol129921_0812.

Organism-specific databases

EchoBASEiEB3432.
EcoGeneiEG13668. ybhL.

Phylogenomic databases

eggNOGiENOG4105HFZ. Bacteria.
COG0670. LUCA.
HOGENOMiHOG000060392.
InParanoidiP0AAC4.
KOiK06890.
OMAiLIIAQFG.
OrthoDBiEOG625K1S.
PhylomeDBiP0AAC4.

Enzyme and pathway databases

BioCyciEcoCyc:G6403-MONOMER.
ECOL316407:JW0769-MONOMER.

Miscellaneous databases

PROiP0AAC4.

Family and domain databases

InterProiIPR006214. Bax_inhibitor_1-related.
[Graphical view]
PANTHERiPTHR23291. PTHR23291. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiYBHL_ECOLI
AccessioniPrimary (citable) accession number: P0AAC4
Secondary accession number(s): P75768
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: September 13, 2005
Last modified: May 11, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.