uspD

Functionⁱ

Required for resistance to DNA-damaging agents.1 Publication

GO - Biological processⁱ

response to stress Source: InterPro

View the complete GO annotation on QuickGO ...

Enzyme and pathway databases

BioCycⁱ	EcoCyc:EG11877-MONOMER.

BioCycⁱ

EcoCyc:EG11877-MONOMER.

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Universal stress protein D
Gene namesⁱ	Name:uspD Synonyms:yiiT Ordered Locus Names:b3923, JW3894
Organismⁱ	Escherichia coli (strain K12)
Taxonomic identifierⁱ	83333 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › Escherichia coli
Proteomesⁱ	UP000000318 Componentⁱ: Chromosome UP000000625 Componentⁱ: Chromosome

Organism-specific databases

EcoGeneⁱ	EG11877. uspD.

EcoGeneⁱ

EG11877. uspD.

Subcellular locationⁱ

Cytoplasm By similarity

GO - Cellular componentⁱ

cytosol
Source: EcoCyc
Inferred from direct assayⁱ
- 17309111

View the complete GO annotation on QuickGO ...

Keywords - Cellular componentⁱ

Cytoplasm

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000147413	1 – 142	Universal stress protein DAdd BLAST		142

Proteomic databases

PaxDbⁱ	P0AAB8.
PRIDEⁱ	P0AAB8.

Expressionⁱ

Inductionⁱ

During growth inhibition caused by the exhaustion of any of a variety of nutrients (carbon, nitrogen, phosphate, sulfate, required amino acid) or by the presence of a variety of toxic agents. Positively regulated by guanosine 3',5'-bisphosphate (ppGpp) and by a RecA/FtsK-dependent regulatory pathway.1 Publication

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	4261396. 7 interactors.
Database of interacting proteins More...DIPⁱ	DIP-35856N.
IntActⁱ	P0AAB8. 7 interactors.
STRINGⁱ	316385.ECDH10B_4112.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P0AAB8.
SMRⁱ	P0AAB8.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the universal stress protein A family.Curated

Phylogenomic databases

eggNOGⁱ	COG0589. LUCA.
HOGENOMⁱ	HOG000238899.
InParanoidⁱ	P0AAB8.
KEGG Orthology (KO) More...KOⁱ	K14065.
OMAⁱ	MAYKHIA.
PhylomeDBⁱ	P0AAB8.

Family and domain databases

Gene3Dⁱ	3.40.50.620. 1 hit.
InterProⁱ	View protein in InterPro IPR014729. Rossmann-like_a/b/a_fold. IPR006015. Universal_stress_UspA. IPR006016. UspA.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00582. Usp. 1 hit.
PIRSFⁱ	PIRSF006276. UspA. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

P0AAB8-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MAYKHIGVAI SGNEEDALLV NKALELARHN DAHLTLIHID DGLSELYPGI 
        60         70         80         90        100
YFPATEDILQ LLKNKSDNKL YKLTKNIQWP KTKLRIERGE MPETLLEIMQ 
       110        120        130        140 
KEQCDLLVCG HHHSFINRLM PAYRGMINKM SADLLIVPFI DK

Length:142

Mass (Da):16,293

Last modified:September 13, 2005 - v1

Checksum:ⁱ0684CAA0EBE1CF6C

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	L19201 Genomic DNA. Translation: AAB03055.1. U00096 Genomic DNA. Translation: AAC76905.1. AP009048 Genomic DNA. Translation: BAE77387.1.
PIRⁱ	S40866.
NCBI Reference Sequences More...RefSeqⁱ	NP_418358.1. NC_000913.3. WP_000323556.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaⁱ	AAC76905; AAC76905; b3923. BAE77387; BAE77387; BAE77387.
GeneIDⁱ	948415.
KEGGⁱ	ecj:JW3894. eco:b3923.
PATRICⁱ	fig\|1411691.4.peg.2782.

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
P0AAB8	P0AAB9 I6G3B8 A0A222QTC1 W1ARN9 A0A1S6TJ71 A0A0I4N067 J7QAV3 A0A1W2N3M8 F4SRY2 I4S5I2 +77	Shigella flexneri Shigella flexneri 1235-66 Escherichia coli NCCP15648 Klebsiella pneumoniae IS22 Escherichia coli M8 Shigella sonnei Escherichia coli Escherichia coli H736 Escherichia coli 541-15 Shigella boydii And more	142	UniRef100_P0AAB8	Cluster: Universal stress protein D	88

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
P0AAB8	P0AAB9 I6G3B8 A0A222QTC1 W1ARN9 A0A1S6TJ71 A0A0I4N067 J7QAV3 A0A1W2N3M8 F4SRY2 I4S5I2 +276	Shigella flexneri Shigella flexneri 1235-66 Escherichia coli NCCP15648 Klebsiella pneumoniae IS22 Escherichia coli M8 Shigella sonnei Escherichia coli Escherichia coli H736 Escherichia coli 541-15 Shigella boydii And more	142	UniRef90_P0AAB8	Cluster: Universal stress protein D	287

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
P0AAB8	P0AAB9 I6G3B8 A0A222QTC1 W1ARN9 A0A1S6TJ71 A0A0I4N067 J7QAV3 A0A1W2N3M8 F4SRY2 I4S5I2 +295	Shigella flexneri Shigella flexneri 1235-66 Escherichia coli NCCP15648 Klebsiella pneumoniae IS22 Escherichia coli M8 Shigella sonnei Escherichia coli Escherichia coli H736 Escherichia coli 541-15 Shigella boydii And more	142	UniRef50_P0AAB8	Cluster: Universal stress protein D	306

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	L19201 Genomic DNA. Translation: AAB03055.1. U00096 Genomic DNA. Translation: AAC76905.1. AP009048 Genomic DNA. Translation: BAE77387.1.
PIRⁱ	S40866.
NCBI Reference Sequences More...RefSeqⁱ	NP_418358.1. NC_000913.3. WP_000323556.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortalⁱ	P0AAB8.
SMRⁱ	P0AAB8.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	4261396. 7 interactors.
Database of interacting proteins More...DIPⁱ	DIP-35856N.
IntActⁱ	P0AAB8. 7 interactors.
STRINGⁱ	316385.ECDH10B_4112.

Proteomic databases

PaxDbⁱ	P0AAB8.
PRIDEⁱ	P0AAB8.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	AAC76905; AAC76905; b3923. BAE77387; BAE77387; BAE77387.
GeneIDⁱ	948415.
KEGGⁱ	ecj:JW3894. eco:b3923.
PATRICⁱ	fig\|1411691.4.peg.2782.

Organism-specific databases

EchoBASEⁱ	EB1823.
EcoGeneⁱ	EG11877. uspD.

Phylogenomic databases

eggNOGⁱ	COG0589. LUCA.
HOGENOMⁱ	HOG000238899.
InParanoidⁱ	P0AAB8.
KEGG Orthology (KO) More...KOⁱ	K14065.
OMAⁱ	MAYKHIA.
PhylomeDBⁱ	P0AAB8.

Enzyme and pathway databases

BioCycⁱ	EcoCyc:EG11877-MONOMER.

BioCycⁱ

EcoCyc:EG11877-MONOMER.

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:P0AAB8.

PROⁱ

PR:P0AAB8.

Family and domain databases

Gene3Dⁱ	3.40.50.620. 1 hit.
InterProⁱ	View protein in InterPro IPR014729. Rossmann-like_a/b/a_fold. IPR006015. Universal_stress_UspA. IPR006016. UspA.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00582. Usp. 1 hit.
PIRSFⁱ	PIRSF006276. UspA. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	USPD_ECOLI
Accessionⁱ	P0AAB8Primary (citable) accession number: P0AAB8 Secondary accession number(s): P32163, Q2M8L9
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	September 13, 2005
	Last sequence update:	September 13, 2005
	Last modified:	March 28, 2018
	This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Prokaryotic Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

UniProtKB

UniParc

Help

UniRef

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Annotation systems

Supporting data

UniProtKB - P0AAB8 (USPD_ECOLI)

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Universal stress protein D

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

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Functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ