Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Universal stress protein D

Gene

uspD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Required for resistance to DNA-damaging agents.1 Publication

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:EG11877-MONOMER.
ECOL316407:JW3894-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Universal stress protein D
Gene namesi
Name:uspD
Synonyms:yiiT
Ordered Locus Names:b3923, JW3894
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11877. uspD.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 142142Universal stress protein DPRO_0000147413Add
BLAST

Proteomic databases

PaxDbiP0AAB8.
PRIDEiP0AAB8.

Expressioni

Inductioni

During growth inhibition caused by the exhaustion of any of a variety of nutrients (carbon, nitrogen, phosphate, sulfate, required amino acid) or by the presence of a variety of toxic agents. Positively regulated by guanosine 3',5'-bisphosphate (ppGpp) and by a RecA/FtsK-dependent regulatory pathway.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4261396. 7 interactions.
DIPiDIP-35856N.
IntActiP0AAB8. 6 interactions.
STRINGi511145.b3923.

Structurei

3D structure databases

ProteinModelPortaliP0AAB8.
SMRiP0AAB8. Positions 3-138.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the universal stress protein A family.Curated

Phylogenomic databases

eggNOGiCOG0589. LUCA.
HOGENOMiHOG000238899.
InParanoidiP0AAB8.
KOiK14065.
OMAiMAYKHIA.
PhylomeDBiP0AAB8.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
InterProiIPR014729. Rossmann-like_a/b/a_fold.
IPR006015. Universal_stress_UspA.
IPR006016. UspA.
[Graphical view]
PfamiPF00582. Usp. 1 hit.
[Graphical view]
PIRSFiPIRSF006276. UspA. 1 hit.

Sequencei

Sequence statusi: Complete.

P0AAB8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAYKHIGVAI SGNEEDALLV NKALELARHN DAHLTLIHID DGLSELYPGI
60 70 80 90 100
YFPATEDILQ LLKNKSDNKL YKLTKNIQWP KTKLRIERGE MPETLLEIMQ
110 120 130 140
KEQCDLLVCG HHHSFINRLM PAYRGMINKM SADLLIVPFI DK
Length:142
Mass (Da):16,293
Last modified:September 13, 2005 - v1
Checksum:i0684CAA0EBE1CF6C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L19201 Genomic DNA. Translation: AAB03055.1.
U00096 Genomic DNA. Translation: AAC76905.1.
AP009048 Genomic DNA. Translation: BAE77387.1.
PIRiS40866.
RefSeqiNP_418358.1. NC_000913.3.
WP_000323556.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76905; AAC76905; b3923.
BAE77387; BAE77387; BAE77387.
GeneIDi948415.
KEGGiecj:JW3894.
eco:b3923.
PATRICi32123359. VBIEscCol129921_4040.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L19201 Genomic DNA. Translation: AAB03055.1.
U00096 Genomic DNA. Translation: AAC76905.1.
AP009048 Genomic DNA. Translation: BAE77387.1.
PIRiS40866.
RefSeqiNP_418358.1. NC_000913.3.
WP_000323556.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AAB8.
SMRiP0AAB8. Positions 3-138.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261396. 7 interactions.
DIPiDIP-35856N.
IntActiP0AAB8. 6 interactions.
STRINGi511145.b3923.

Proteomic databases

PaxDbiP0AAB8.
PRIDEiP0AAB8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76905; AAC76905; b3923.
BAE77387; BAE77387; BAE77387.
GeneIDi948415.
KEGGiecj:JW3894.
eco:b3923.
PATRICi32123359. VBIEscCol129921_4040.

Organism-specific databases

EchoBASEiEB1823.
EcoGeneiEG11877. uspD.

Phylogenomic databases

eggNOGiCOG0589. LUCA.
HOGENOMiHOG000238899.
InParanoidiP0AAB8.
KOiK14065.
OMAiMAYKHIA.
PhylomeDBiP0AAB8.

Enzyme and pathway databases

BioCyciEcoCyc:EG11877-MONOMER.
ECOL316407:JW3894-MONOMER.

Miscellaneous databases

PROiP0AAB8.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
InterProiIPR014729. Rossmann-like_a/b/a_fold.
IPR006015. Universal_stress_UspA.
IPR006016. UspA.
[Graphical view]
PfamiPF00582. Usp. 1 hit.
[Graphical view]
PIRSFiPIRSF006276. UspA. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUSPD_ECOLI
AccessioniPrimary (citable) accession number: P0AAB8
Secondary accession number(s): P32163, Q2M8L9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: September 13, 2005
Last modified: September 7, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.