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P0AAB7

- GALF_ECO57

UniProt

P0AAB7 - GALF_ECO57

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Protein

UTP--glucose-1-phosphate uridylyltransferase

Gene
galF, wcaN, Z3205, ECs2846
Organism
Escherichia coli O157:H7
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.

Pathwayi

GO - Molecular functioni

  1. enzyme regulator activity Source: InterPro
  2. UTP:glucose-1-phosphate uridylyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. lipopolysaccharide biosynthetic process Source: UniProtKB-UniPathway
  2. UDP-glucose metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Lipopolysaccharide biosynthesis

Enzyme and pathway databases

BioCyciECOL386585:GJFA-2809-MONOMER.
ECOO157:GALF-MONOMER.
UniPathwayiUPA00030.
UPA00215.

Names & Taxonomyi

Protein namesi
Recommended name:
UTP--glucose-1-phosphate uridylyltransferase (EC:2.7.7.9)
Alternative name(s):
Alpha-D-glucosyl-1-phosphate uridylyltransferase
UDP-glucose pyrophosphorylase
Short name:
UDPGP
Uridine diphosphoglucose pyrophosphorylase
Gene namesi
Name:galF
Synonyms:wcaN
Ordered Locus Names:Z3205, ECs2846
OrganismiEscherichia coli O157:H7
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000558: Chromosome, UP000002519: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 297297UTP--glucose-1-phosphate uridylyltransferasePRO_0000201350Add
BLAST

Proteomic databases

PRIDEiP0AAB7.

Interactioni

Protein-protein interaction databases

STRINGi155864.Z3205.

Structurei

3D structure databases

ProteinModelPortaliP0AAB7.
SMRiP0AAB7. Positions 5-293.

Family & Domainsi

Sequence similaritiesi

Belongs to the UDPGP type 2 family.

Phylogenomic databases

eggNOGiCOG1210.
HOGENOMiHOG000283477.
KOiK00963.
OMAiMDEIMTN.
OrthoDBiEOG6Z9B3V.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
InterProiIPR005774. GalF.
IPR005835. NTP_transferase.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PfamiPF00483. NTP_transferase. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 1 hit.
TIGRFAMsiTIGR01105. galF. 1 hit.

Sequencei

Sequence statusi: Complete.

P0AAB7-1 [UniParc]FASTAAdd to Basket

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MTNLKAVIPV AGLGMHMLPA TKAIPKEMLP IVDKPMIQYI VDEIVAAGIK    50
EILLVTHASK NAVENHFDTS YELESLLEQR VKRQLLAEVQ SICPPGVTIM 100
NVRQGEPLGL GHSILCARPA IGDNPFVVVL PDVVIDDASA DPLRYNLAAM 150
IARFNETGRS QVLAKRMPGD LSEYSVIQTK EPLDREGKVS RIVEFIEKPD 200
QPQTLDSDIM AVGRYVLSAD IWPELERTQP GAWGRIQLTD AIAELAKKQS 250
VDAMLMTGDS YDCGKKMGYM QAFVKYGLRN LKEGAKFRKG IEKLLSE 297
Length:297
Mass (Da):32,829
Last modified:September 13, 2005 - v1
Checksum:i6F85D6BB12C0C5A8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE005174 Genomic DNA. Translation: AAG57101.1.
BA000007 Genomic DNA. Translation: BAB36269.1.
PIRiA85830.
F90984.
RefSeqiNP_288547.1. NC_002655.2.
NP_310873.1. NC_002695.1.

Genome annotation databases

EnsemblBacteriaiAAG57101; AAG57101; Z3205.
BAB36269; BAB36269; BAB36269.
GeneIDi914113.
962100.
KEGGiece:Z3205.
ecs:ECs2846.
PATRICi18355076. VBIEscCol44059_2739.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE005174 Genomic DNA. Translation: AAG57101.1 .
BA000007 Genomic DNA. Translation: BAB36269.1 .
PIRi A85830.
F90984.
RefSeqi NP_288547.1. NC_002655.2.
NP_310873.1. NC_002695.1.

3D structure databases

ProteinModelPortali P0AAB7.
SMRi P0AAB7. Positions 5-293.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 155864.Z3205.

Proteomic databases

PRIDEi P0AAB7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAG57101 ; AAG57101 ; Z3205 .
BAB36269 ; BAB36269 ; BAB36269 .
GeneIDi 914113.
962100.
KEGGi ece:Z3205.
ecs:ECs2846.
PATRICi 18355076. VBIEscCol44059_2739.

Phylogenomic databases

eggNOGi COG1210.
HOGENOMi HOG000283477.
KOi K00963.
OMAi MDEIMTN.
OrthoDBi EOG6Z9B3V.

Enzyme and pathway databases

UniPathwayi UPA00030 .
UPA00215 .
BioCyci ECOL386585:GJFA-2809-MONOMER.
ECOO157:GALF-MONOMER.

Family and domain databases

Gene3Di 3.90.550.10. 1 hit.
InterProi IPR005774. GalF.
IPR005835. NTP_transferase.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view ]
Pfami PF00483. NTP_transferase. 1 hit.
[Graphical view ]
SUPFAMi SSF53448. SSF53448. 1 hit.
TIGRFAMsi TIGR01105. galF. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: O157:H7 / EDL933 / ATCC 700927 / EHEC.
  2. "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12."
    Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K., Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.
    , Kuhara S., Shiba T., Hattori M., Shinagawa H.
    DNA Res. 8:11-22(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: O157:H7 / Sakai / RIMD 0509952 / EHEC.

Entry informationi

Entry nameiGALF_ECO57
AccessioniPrimary (citable) accession number: P0AAB7
Secondary accession number(s): P71245, P78083, P97192
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: September 13, 2005
Last modified: June 11, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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