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Protein

Zinc resistance-associated protein

Gene

zraP

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Binds zinc. Could be an important component of the zinc-balancing mechanism.

GO - Molecular functioni

  • cobalt ion binding Source: EcoCyc
  • copper ion binding Source: EcoCyc
  • nickel cation binding Source: EcoCyc
  • zinc ion binding Source: EcoCyc

Keywordsi

LigandZinc

Enzyme and pathway databases

BioCyciEcoCyc:EG11918-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc resistance-associated protein
Gene namesi
Name:zraP
Synonyms:yjaI, zra
Ordered Locus Names:b4002, JW5546
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11918 zraP

Subcellular locationi

GO - Cellular componenti

  • outer membrane-bounded periplasmic space Source: EcoCyc

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 261 PublicationAdd BLAST26
ChainiPRO_000002272027 – 141Zinc resistance-associated proteinAdd BLAST115

Proteomic databases

PaxDbiP0AAA9
PRIDEiP0AAA9

Interactioni

Protein-protein interaction databases

BioGridi42595258 interactors.
STRINGi316385.ECDH10B_4191

Structurei

3D structure databases

ProteinModelPortaliP0AAA9
SMRiP0AAA9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ZraP family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105JBU Bacteria
COG3678 LUCA
HOGENOMiHOG000126776
KOiK07803
OMAiGMGYGDC

Family and domain databases

InterProiView protein in InterPro
IPR025961 Metal_resist
IPR020365 Zn_resistance-assoc_prot_ZraP
PfamiView protein in Pfam
PF13801 Metal_resist, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD097062 Zn_resistance-assoc_prot_ZraP, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0AAA9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRNTKIALV MMALSAMAMG STSAFAHGGH GMWQQNAAPL TSEQQTAWQK
60 70 80 90 100
IHNDFYAQSS ALQQQLVTKR YEYNALLAAN PPDSSKINAV AKEMENLRQS
110 120 130 140
LDELRVKRDI AMAEAGIPRG AGMGMGYGGC GGGGHMGMGH W
Length:141
Mass (Da):15,199
Last modified:September 13, 2005 - v1
Checksum:i392A8B29CEBECC1B
GO

Sequence cautioni

The sequence AAC43100 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00006 Genomic DNA Translation: AAC43100.1 Different initiation.
U00096 Genomic DNA Translation: AAC76976.2
AP009048 Genomic DNA Translation: BAE77317.1
PIRiE65207
RefSeqiNP_418430.2, NC_000913.3
WP_000828222.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC76976; AAC76976; b4002
BAE77317; BAE77317; BAE77317
GeneIDi948507
KEGGiecj:JW5546
eco:b4002
PATRICifig|1411691.4.peg.2709

Similar proteinsi

Entry informationi

Entry nameiZRAP_ECOLI
AccessioniPrimary (citable) accession number: P0AAA9
Secondary accession number(s): P32682, Q2M8T9, Q8X6X2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: September 13, 2005
Last modified: March 28, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome