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P0AAA7 (WZXE_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein WzxE
Gene names
Name:wzxE
Synonyms:wzx, yifJ
Ordered Locus Names:b3792, JW3766
OrganismEscherichia coli (strain K12) [Reference proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia ›

Protein attributes

Sequence length416 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Ontologies

Keywords
   Cellular componentCell inner membrane
Cell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processenterobacterial common antigen biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 416416Protein WzxE
PRO_0000065989

Regions

Topological domain1 – 1212Cytoplasmic Potential
Transmembrane13 – 3523Helical; Potential
Topological domain36 – 449Periplasmic Potential
Transmembrane45 – 6723Helical; Potential
Topological domain68 – 7811Cytoplasmic Potential
Transmembrane79 – 10123Helical; Potential
Topological domain102 – 11514Periplasmic Potential
Transmembrane116 – 13823Helical; Potential
Topological domain139 – 1446Cytoplasmic Potential
Transmembrane145 – 16723Helical; Potential
Topological domain168 – 1769Periplasmic Potential
Transmembrane177 – 19923Helical; Potential
Topological domain200 – 21920Cytoplasmic Potential
Transmembrane220 – 23819Helical; Potential
Topological domain239 – 25214Periplasmic Potential
Transmembrane253 – 27523Helical; Potential
Topological domain276 – 29520Cytoplasmic Potential
Transmembrane296 – 31823Helical; Potential
Topological domain319 – 33214Periplasmic Potential
Transmembrane333 – 35523Helical; Potential
Topological domain356 – 3616Cytoplasmic Potential
Transmembrane362 – 38423Helical; Potential
Topological domain385 – 3895Periplasmic Potential
Transmembrane390 – 41223Helical; Potential
Topological domain413 – 4164Cytoplasmic Potential

Sequences

Sequence LengthMass (Da)Tools
P0AAA7 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: 001690A4E86CADF5

FASTA41644,960
        10         20         30         40         50         60 
MSLAKASLWT AASTLVKIGA GLLVGKLLAV SFGPAGLGLA ANFRQLITVL GVLAGAGIFN 

        70         80         90        100        110        120 
GVTKYVAQYH DNPQQLRRVV GTSSAMVLGF STLMALVFVL AAAPISQGLF GNTDYQGLVR 

       130        140        150        160        170        180 
LVALVQMGIA WGNLLLALMK GFRDAAGNAL SLIVGSLIGV LAYYVSYRLG GYEGALLGLA 

       190        200        210        220        230        240 
LIPALVVIPA AIMLIKRGVI PLSYLKPSWD NGLAGQLSKF TLMALITSVT LPVAYIMMRK 

       250        260        270        280        290        300 
LLAAQYSWDE VGIWQGVSSI SDAYLQFITA SFSVYLLPTL SRLTEKRDIT REVVKSLKFV 

       310        320        330        340        350        360 
LPAVAAASFT VWLLRDFAIW LLLSNKFTAM RDLFAWQLVG DVLKVGAYVF GYLVIAKASL 

       370        380        390        400        410 
RFYILAEVSQ FTLLMVFAHW LIPAHGALGA AQAYMATYIV YFSLCCGVFL LWRRRA

« Hide

References

[1]"Analysis of the Escherichia coli genome: DNA sequence of the region from 84.5 to 86.5 minutes."
Daniels D.L., Plunkett G. III, Burland V.D., Blattner F.R.
Science 257:771-778(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[2]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[3]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]"Global topology analysis of the Escherichia coli inner membrane proteome."
Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
Strain: K12 / MG1655 / ATCC 47076.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		M87049 Genomic DNA. Translation: AAA67592.1.
U00096 Genomic DNA. Translation: AAC76797.1.
AP009048 Genomic DNA. Translation: BAE77506.1.
PIRC65183.
RefSeqNP_418239.1. NC_000913.2.
YP_491647.1. NC_007779.1.

3D structure databases

ProteinModelPortalP0AAA7.
ModBaseSearch...

Protein-protein interaction databases

STRING511145.b3792.

Protein family/group databases

TCDB2.A.66.2.3. multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) flippase superfamily.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC76797; AAC76797; b3792.
BAE77506; BAE77506; BAE77506.
GeneID12933113.
948294.
KEGGecj:Y75_p3383.
eco:b3792.
PATRIC32123077. VBIEscCol129921_3908.

Organism-specific databases

EchoBASEEB1449.
EcoGeneEG11486. wzxE.

Phylogenomic databases

eggNOGCOG2244.
HOGENOMHOG000126459.
KOK16693.
OMATAFSHWL.
ProtClustDBPRK15099.

Enzyme and pathway databases

BioCycEcoCyc:EG11486-MONOMER.
ECOL316407:JW3766-MONOMER.
UniPathwayUPA00566.

Gene expression databases

GenevestigatorP0AAA7.

Family and domain databases

InterProIPR002797. Polysacc_synth.
[Graphical view]
PfamPF01943. Polysacc_synt. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameWZXE_ECOLI
AccessionPrimary (citable) accession number: P0AAA7
Secondary accession number(s): P27834, Q2M8A0
Entry history
Integrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: September 13, 2005
Last modified: May 1, 2013
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene

PATHWAY comments

Index of metabolic and biosynthesis pathways

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