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Protein

Putative L,D-transpeptidase YafK

Gene

yafK

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Hydrolase, Transferase

Keywords - Biological processi

Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

BioCyciEcoCyc:G6108-MONOMER.
ECOL316407:JW0214-MONOMER.
UniPathwayiUPA00219.

Protein family/group databases

MEROPSiC82.A01.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative L,D-transpeptidase YafK (EC:2.-.-.-)
Gene namesi
Name:yafK
Ordered Locus Names:b0224, JW0214
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13148. yafK.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_000001378420 – 246Putative L,D-transpeptidase YafKAdd BLAST227

Proteomic databases

PaxDbiP0AA99.
PRIDEiP0AA99.

Interactioni

Protein-protein interaction databases

BioGridi4262122. 20 interactors.
STRINGi511145.b0224.

Structurei

3D structure databases

ProteinModelPortaliP0AA99.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the YkuD family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105F7V. Bacteria.
COG3034. LUCA.
HOGENOMiHOG000117032.
InParanoidiP0AA99.
OMAiCYAMTDT.
PhylomeDBiP0AA99.

Family and domain databases

InterProiIPR005490. LD_TPept_cat_dom.
[Graphical view]
PfamiPF03734. YkuD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0AA99-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRKIALILAM LLIPCVSFAG LLGSSSSTTP VSKEYKQQLM GSPVYIQIFK
60 70 80 90 100
EERTLDLYVK MGEQYQLLDS YKICKYSGGL GPKQRQGDFK SPEGFYSVQR
110 120 130 140 150
NQLKPDSRYY KAINIGFPNA YDRAHGYEGK YLMIHGDCVS IGCYAMTNQG
160 170 180 190 200
IDEIFQFVTG ALVFGQPSVQ VSIYPFRMTD ANMKRHKYSN FKDFWEQLKP
210 220 230 240
GYDYFEQTRK PPTVSVVNGR YVVSKPLSHE VVQPQLASNY TLPEAK
Length:246
Mass (Da):28,021
Last modified:September 13, 2005 - v1
Checksum:iD2B6686353D9735A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D38582 Genomic DNA. Translation: BAA07586.1.
U70214 Genomic DNA. Translation: AAB08646.1.
U00096 Genomic DNA. Translation: AAC73328.1.
AP009048 Genomic DNA. Translation: BAA77894.1.
PIRiA64747.
RefSeqiNP_414759.1. NC_000913.3.
WP_001225679.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73328; AAC73328; b0224.
BAA77894; BAA77894; BAA77894.
GeneIDi944910.
KEGGiecj:JW0214.
eco:b0224.
PATRICi32115563. VBIEscCol129921_0226.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D38582 Genomic DNA. Translation: BAA07586.1.
U70214 Genomic DNA. Translation: AAB08646.1.
U00096 Genomic DNA. Translation: AAC73328.1.
AP009048 Genomic DNA. Translation: BAA77894.1.
PIRiA64747.
RefSeqiNP_414759.1. NC_000913.3.
WP_001225679.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AA99.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262122. 20 interactors.
STRINGi511145.b0224.

Protein family/group databases

MEROPSiC82.A01.

Proteomic databases

PaxDbiP0AA99.
PRIDEiP0AA99.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73328; AAC73328; b0224.
BAA77894; BAA77894; BAA77894.
GeneIDi944910.
KEGGiecj:JW0214.
eco:b0224.
PATRICi32115563. VBIEscCol129921_0226.

Organism-specific databases

EchoBASEiEB2942.
EcoGeneiEG13148. yafK.

Phylogenomic databases

eggNOGiENOG4105F7V. Bacteria.
COG3034. LUCA.
HOGENOMiHOG000117032.
InParanoidiP0AA99.
OMAiCYAMTDT.
PhylomeDBiP0AA99.

Enzyme and pathway databases

UniPathwayiUPA00219.
BioCyciEcoCyc:G6108-MONOMER.
ECOL316407:JW0214-MONOMER.

Miscellaneous databases

PROiP0AA99.

Family and domain databases

InterProiIPR005490. LD_TPept_cat_dom.
[Graphical view]
PfamiPF03734. YkuD. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYAFK_ECOLI
AccessioniPrimary (citable) accession number: P0AA99
Secondary accession number(s): Q47148
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: September 13, 2005
Last modified: November 2, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.