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Protein

Putative L,D-transpeptidase YafK

Gene

yafK

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Hydrolase, Transferase
Biological processCell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

BioCyciEcoCyc:G6108-MONOMER
UniPathwayiUPA00219

Protein family/group databases

MEROPSiC82.A01

Names & Taxonomyi

Protein namesi
Recommended name:
Putative L,D-transpeptidase YafK (EC:2.-.-.-)
Gene namesi
Name:yafK
Ordered Locus Names:b0224, JW0214
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13148 yafK

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_000001378420 – 246Putative L,D-transpeptidase YafKAdd BLAST227

Proteomic databases

PaxDbiP0AA99
PRIDEiP0AA99

Interactioni

Protein-protein interaction databases

BioGridi4262122, 20 interactors
STRINGi316385.ECDH10B_0206

Structurei

3D structure databases

ProteinModelPortaliP0AA99
SMRiP0AA99
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the YkuD family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105F7V Bacteria
COG3034 LUCA
HOGENOMiHOG000117032
InParanoidiP0AA99
OMAiMAQIYAF
PhylomeDBiP0AA99

Family and domain databases

InterProiView protein in InterPro
IPR005490 LD_TPept_cat_dom
IPR038063 Transpep_catalytic_dom
PfamiView protein in Pfam
PF03734 YkuD, 1 hit
SUPFAMiSSF141523 SSF141523, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0AA99-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRKIALILAM LLIPCVSFAG LLGSSSSTTP VSKEYKQQLM GSPVYIQIFK
60 70 80 90 100
EERTLDLYVK MGEQYQLLDS YKICKYSGGL GPKQRQGDFK SPEGFYSVQR
110 120 130 140 150
NQLKPDSRYY KAINIGFPNA YDRAHGYEGK YLMIHGDCVS IGCYAMTNQG
160 170 180 190 200
IDEIFQFVTG ALVFGQPSVQ VSIYPFRMTD ANMKRHKYSN FKDFWEQLKP
210 220 230 240
GYDYFEQTRK PPTVSVVNGR YVVSKPLSHE VVQPQLASNY TLPEAK
Length:246
Mass (Da):28,021
Last modified:September 13, 2005 - v1
Checksum:iD2B6686353D9735A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D38582 Genomic DNA Translation: BAA07586.1
U70214 Genomic DNA Translation: AAB08646.1
U00096 Genomic DNA Translation: AAC73328.1
AP009048 Genomic DNA Translation: BAA77894.1
PIRiA64747
RefSeqiNP_414759.1, NC_000913.3
WP_001225679.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73328; AAC73328; b0224
BAA77894; BAA77894; BAA77894
GeneIDi944910
KEGGiecj:JW0214
eco:b0224
PATRICifig|511145.12.peg.226

Similar proteinsi

Entry informationi

Entry nameiYAFK_ECOLI
AccessioniPrimary (citable) accession number: P0AA99
Secondary accession number(s): Q47148
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: September 13, 2005
Last modified: March 28, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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