Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable galactarate transporter

Gene

garP

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Uptake of D-galactarate.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:YHAU-MONOMER.
ECOL316407:JW3096-MONOMER.
MetaCyc:YHAU-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable galactarate transporter
Alternative name(s):
D-galactarate permease
Gene namesi
Name:garP
Synonyms:yhaU
Ordered Locus Names:b3127, JW3096
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12760. garP.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 1111CytoplasmicSequence analysisAdd
BLAST
Transmembranei12 – 3221HelicalSequence analysisAdd
BLAST
Topological domaini33 – 5624PeriplasmicSequence analysisAdd
BLAST
Transmembranei57 – 7721HelicalSequence analysisAdd
BLAST
Topological domaini78 – 8912CytoplasmicSequence analysisAdd
BLAST
Transmembranei90 – 11021HelicalSequence analysisAdd
BLAST
Transmembranei111 – 13121HelicalSequence analysisAdd
BLAST
Topological domaini132 – 15726CytoplasmicSequence analysisAdd
BLAST
Transmembranei158 – 17821HelicalSequence analysisAdd
BLAST
Transmembranei179 – 19921HelicalSequence analysisAdd
BLAST
Topological domaini200 – 25253CytoplasmicSequence analysisAdd
BLAST
Transmembranei253 – 27321HelicalSequence analysisAdd
BLAST
Topological domaini274 – 28815PeriplasmicSequence analysisAdd
BLAST
Transmembranei289 – 30921HelicalSequence analysisAdd
BLAST
Topological domaini310 – 31910CytoplasmicSequence analysis
Transmembranei320 – 34021HelicalSequence analysisAdd
BLAST
Topological domaini341 – 35010PeriplasmicSequence analysis
Transmembranei351 – 37121HelicalSequence analysisAdd
BLAST
Topological domaini372 – 38514CytoplasmicSequence analysisAdd
BLAST
Transmembranei386 – 40621HelicalSequence analysisAdd
BLAST
Topological domaini407 – 4137PeriplasmicSequence analysis
Transmembranei414 – 43421HelicalSequence analysisAdd
BLAST
Topological domaini435 – 44410CytoplasmicSequence analysis

GO - Cellular componenti

  • integral component of membrane Source: GO_Central
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 444444Probable galactarate transporterPRO_0000121382Add
BLAST

Proteomic databases

PaxDbiP0AA80.

Interactioni

Protein-protein interaction databases

BioGridi4259486. 14 interactions.
STRINGi511145.b3127.

Structurei

3D structure databases

ProteinModelPortaliP0AA80.
SMRiP0AA80. Positions 16-441.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105DJB. Bacteria.
ENOG410XPWC. LUCA.
HOGENOMiHOG000113642.
InParanoidiP0AA80.
KOiK12299.
OMAiQTPAMAV.
PhylomeDBiP0AA80.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR004744. Dgal_transporter.
IPR011701. MFS.
IPR020846. MFS_dom.
IPR000849. Sugar_P_transporter.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
PIRSFiPIRSF002808. Hexose_phosphate_transp. 1 hit.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00893. 2A0114. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AA80-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MILDTVDEKK KGVHTRYLIL LIIFIVTAVN YADRATLSIA GTEVAKELQL
60 70 80 90 100
SAVSMGYIFS AFGWAYLLMQ IPGGWLLDKF GSKKVYTYSL FFWSLFTFLQ
110 120 130 140 150
GFVDMFPLAW AGISMFFMRF MLGFSEAPSF PANARIVAAW FPTKERGTAS
160 170 180 190 200
AIFNSAQYFS LALFSPLLGW LTFAWGWEHV FTVMGVIGFV LTALWIKLIH
210 220 230 240 250
NPTDHPRMSA EELKFISENG AVVDMDHKKP GSAAASGPKL HYIKQLLSNR
260 270 280 290 300
MMLGVFFGQY FINTITWFFL TWFPIYLVQE KGMSILKVGL VASIPALCGF
310 320 330 340 350
AGGVLGGVFS DYLIKRGLSL TLARKLPIVL GMLLASTIIL CNYTNNTTLV
360 370 380 390 400
VMLMALAFFG KGFGALGWPV ISDTAPKEIV GLCGGVFNVF GNVASIVTPL
410 420 430 440
VIGYLVSELH SFNAALVFVG CSALMAMVCY LFVVGDIKRM ELQK
Length:444
Mass (Da):49,009
Last modified:September 13, 2005 - v1
Checksum:i48FA27023B0C9D30
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA57930.1.
U00096 Genomic DNA. Translation: AAC76161.1.
AP009048 Genomic DNA. Translation: BAE77174.1.
PIRiC65102.
RefSeqiNP_417596.1. NC_000913.3.
WP_000599636.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76161; AAC76161; b3127.
BAE77174; BAE77174; BAE77174.
GeneIDi947642.
KEGGiecj:JW3096.
eco:b3127.
PATRICi32121668. VBIEscCol129921_3220.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18997 Genomic DNA. Translation: AAA57930.1.
U00096 Genomic DNA. Translation: AAC76161.1.
AP009048 Genomic DNA. Translation: BAE77174.1.
PIRiC65102.
RefSeqiNP_417596.1. NC_000913.3.
WP_000599636.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AA80.
SMRiP0AA80. Positions 16-441.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259486. 14 interactions.
STRINGi511145.b3127.

Proteomic databases

PaxDbiP0AA80.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76161; AAC76161; b3127.
BAE77174; BAE77174; BAE77174.
GeneIDi947642.
KEGGiecj:JW3096.
eco:b3127.
PATRICi32121668. VBIEscCol129921_3220.

Organism-specific databases

EchoBASEiEB2613.
EcoGeneiEG12760. garP.

Phylogenomic databases

eggNOGiENOG4105DJB. Bacteria.
ENOG410XPWC. LUCA.
HOGENOMiHOG000113642.
InParanoidiP0AA80.
KOiK12299.
OMAiQTPAMAV.
PhylomeDBiP0AA80.

Enzyme and pathway databases

BioCyciEcoCyc:YHAU-MONOMER.
ECOL316407:JW3096-MONOMER.
MetaCyc:YHAU-MONOMER.

Miscellaneous databases

PROiP0AA80.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR004744. Dgal_transporter.
IPR011701. MFS.
IPR020846. MFS_dom.
IPR000849. Sugar_P_transporter.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
PIRSFiPIRSF002808. Hexose_phosphate_transp. 1 hit.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00893. 2A0114. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGARP_ECOLI
AccessioniPrimary (citable) accession number: P0AA80
Secondary accession number(s): P42613, Q2M982
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: September 13, 2005
Last modified: September 7, 2016
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.