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Protein

D-galactonate transporter

Gene

dgoT

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Intake of galactonate into the cell.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:YIDT-MONOMER.
ECOL316407:JW5859-MONOMER.

Protein family/group databases

TCDBi2.A.1.14.7. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
D-galactonate transporter
Gene namesi
Name:dgoT
Synonyms:yidT
Ordered Locus Names:b3691, JW5859
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11715. dgoT.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 17PeriplasmicSequence analysisAdd BLAST17
Transmembranei18 – 38HelicalSequence analysisAdd BLAST21
Topological domaini39 – 54CytoplasmicSequence analysisAdd BLAST16
Transmembranei55 – 75HelicalSequence analysisAdd BLAST21
Topological domaini76 – 84PeriplasmicSequence analysis9
Transmembranei85 – 105HelicalSequence analysisAdd BLAST21
Topological domaini106 – 142CytoplasmicSequence analysisAdd BLAST37
Transmembranei143 – 163HelicalSequence analysisAdd BLAST21
Topological domaini164 – 167PeriplasmicSequence analysis4
Transmembranei168 – 188HelicalSequence analysisAdd BLAST21
Topological domaini189 – 242CytoplasmicSequence analysisAdd BLAST54
Transmembranei243 – 263HelicalSequence analysisAdd BLAST21
Topological domaini264 – 283PeriplasmicSequence analysisAdd BLAST20
Transmembranei284 – 304HelicalSequence analysisAdd BLAST21
Topological domaini305 – 309CytoplasmicSequence analysis5
Transmembranei310 – 330HelicalSequence analysisAdd BLAST21
Topological domaini331 – 337PeriplasmicSequence analysis7
Transmembranei338 – 358HelicalSequence analysisAdd BLAST21
Topological domaini359 – 375CytoplasmicSequence analysisAdd BLAST17
Transmembranei376 – 396HelicalSequence analysisAdd BLAST21
Topological domaini397 – 403PeriplasmicSequence analysis7
Transmembranei404 – 424HelicalSequence analysisAdd BLAST21
Topological domaini425 – 430CytoplasmicSequence analysis6

GO - Cellular componenti

  • integral component of membrane Source: GO_Central
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001213771 – 430D-galactonate transporterAdd BLAST430

Proteomic databases

PaxDbiP0AA76.
PRIDEiP0AA76.

Interactioni

Protein-protein interaction databases

BioGridi4263278. 7 interactors.
DIPiDIP-9436N.
STRINGi511145.b3691.

Structurei

3D structure databases

ProteinModelPortaliP0AA76.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105DJB. Bacteria.
ENOG410XPWC. LUCA.
HOGENOMiHOG000113642.
InParanoidiP0AA76.
KOiK08194.
OMAiIWIMALM.
PhylomeDBiP0AA76.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR004744. Dgal_transporter.
IPR011701. MFS.
IPR020846. MFS_dom.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00893. 2A0114. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AA76-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDIPVNAAKP GRRRYLTLVM IFITVVICYV DRANLAVASA HIQEEFGITK
60 70 80 90 100
AEMGYVFSAF AWLYTLCQIP GGWFLDRVGS RVTYFIAIFG WSVATLFQGF
110 120 130 140 150
ATGLMSLIGL RAITGIFEAP AFPTNNRMVT SWFPEHERAS AVGFYTSGQF
160 170 180 190 200
VGLAFLTPLL IWIQEMLSWH WVFIVTGGIG IIWSLIWFKV YQPPRLTKGI
210 220 230 240 250
SKAELDYIRD GGGLVDGDAP VKKEARQPLT AKDWKLVFHR KLIGVYLGQF
260 270 280 290 300
AVASTLWFFL TWFPNYLTQE KGITALKAGF MTTVPFLAAF VGVLLSGWVA
310 320 330 340 350
DLLVRKGFSL GFARKTPIIC GLLISTCIMG ANYTNDPMMI MCLMALAFFG
360 370 380 390 400
NGFASITWSL VSSLAPMRLI GLTGGVFNFA GGLGGITVPL VVGYLAQGYG
410 420 430
FAPALVYISA VALIGALSYI LLVGDVKRVG
Length:430
Mass (Da):47,077
Last modified:September 13, 2005 - v1
Checksum:i86B1902777F2E461
GO

Sequence cautioni

The sequence AAA62043 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L10328 Genomic DNA. Translation: AAA62043.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76714.2.
AP009048 Genomic DNA. Translation: BAE77603.1.
PIRiD65171.
RefSeqiNP_418146.4. NC_000913.3.
WP_000354284.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76714; AAC76714; b3691.
BAE77603; BAE77603; BAE77603.
GeneIDi948196.
KEGGiecj:JW5859.
eco:b3691.
PATRICi32122877. VBIEscCol129921_3814.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L10328 Genomic DNA. Translation: AAA62043.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76714.2.
AP009048 Genomic DNA. Translation: BAE77603.1.
PIRiD65171.
RefSeqiNP_418146.4. NC_000913.3.
WP_000354284.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AA76.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263278. 7 interactors.
DIPiDIP-9436N.
STRINGi511145.b3691.

Protein family/group databases

TCDBi2.A.1.14.7. the major facilitator superfamily (mfs).

Proteomic databases

PaxDbiP0AA76.
PRIDEiP0AA76.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76714; AAC76714; b3691.
BAE77603; BAE77603; BAE77603.
GeneIDi948196.
KEGGiecj:JW5859.
eco:b3691.
PATRICi32122877. VBIEscCol129921_3814.

Organism-specific databases

EchoBASEiEB1666.
EcoGeneiEG11715. dgoT.

Phylogenomic databases

eggNOGiENOG4105DJB. Bacteria.
ENOG410XPWC. LUCA.
HOGENOMiHOG000113642.
InParanoidiP0AA76.
KOiK08194.
OMAiIWIMALM.
PhylomeDBiP0AA76.

Enzyme and pathway databases

BioCyciEcoCyc:YIDT-MONOMER.
ECOL316407:JW5859-MONOMER.

Miscellaneous databases

PROiP0AA76.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR004744. Dgal_transporter.
IPR011701. MFS.
IPR020846. MFS_dom.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00893. 2A0114. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDGOT_ECOLI
AccessioniPrimary (citable) accession number: P0AA76
Secondary accession number(s): P31457, Q2M803
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: September 13, 2005
Last modified: November 2, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.