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Protein

D-galactonate transporter

Gene

dgoT

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Intake of galactonate into the cell.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:YIDT-MONOMER.
ECOL316407:JW5859-MONOMER.

Protein family/group databases

TCDBi2.A.1.14.7. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
D-galactonate transporter
Gene namesi
Name:dgoT
Synonyms:yidT
Ordered Locus Names:b3691, JW5859
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11715. dgoT.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 1717PeriplasmicSequence analysisAdd
BLAST
Transmembranei18 – 3821HelicalSequence analysisAdd
BLAST
Topological domaini39 – 5416CytoplasmicSequence analysisAdd
BLAST
Transmembranei55 – 7521HelicalSequence analysisAdd
BLAST
Topological domaini76 – 849PeriplasmicSequence analysis
Transmembranei85 – 10521HelicalSequence analysisAdd
BLAST
Topological domaini106 – 14237CytoplasmicSequence analysisAdd
BLAST
Transmembranei143 – 16321HelicalSequence analysisAdd
BLAST
Topological domaini164 – 1674PeriplasmicSequence analysis
Transmembranei168 – 18821HelicalSequence analysisAdd
BLAST
Topological domaini189 – 24254CytoplasmicSequence analysisAdd
BLAST
Transmembranei243 – 26321HelicalSequence analysisAdd
BLAST
Topological domaini264 – 28320PeriplasmicSequence analysisAdd
BLAST
Transmembranei284 – 30421HelicalSequence analysisAdd
BLAST
Topological domaini305 – 3095CytoplasmicSequence analysis
Transmembranei310 – 33021HelicalSequence analysisAdd
BLAST
Topological domaini331 – 3377PeriplasmicSequence analysis
Transmembranei338 – 35821HelicalSequence analysisAdd
BLAST
Topological domaini359 – 37517CytoplasmicSequence analysisAdd
BLAST
Transmembranei376 – 39621HelicalSequence analysisAdd
BLAST
Topological domaini397 – 4037PeriplasmicSequence analysis
Transmembranei404 – 42421HelicalSequence analysisAdd
BLAST
Topological domaini425 – 4306CytoplasmicSequence analysis

GO - Cellular componenti

  • integral component of membrane Source: GO_Central
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 430430D-galactonate transporterPRO_0000121377Add
BLAST

Proteomic databases

PaxDbiP0AA76.

Interactioni

Protein-protein interaction databases

BioGridi4263278. 7 interactions.
DIPiDIP-9436N.
STRINGi511145.b3691.

Structurei

3D structure databases

ProteinModelPortaliP0AA76.
SMRiP0AA76. Positions 12-428.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105DJB. Bacteria.
ENOG410XPWC. LUCA.
HOGENOMiHOG000113642.
InParanoidiP0AA76.
KOiK08194.
OMAiIWIMALM.
PhylomeDBiP0AA76.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR004744. Dgal_transporter.
IPR011701. MFS.
IPR020846. MFS_dom.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00893. 2A0114. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0AA76-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDIPVNAAKP GRRRYLTLVM IFITVVICYV DRANLAVASA HIQEEFGITK
60 70 80 90 100
AEMGYVFSAF AWLYTLCQIP GGWFLDRVGS RVTYFIAIFG WSVATLFQGF
110 120 130 140 150
ATGLMSLIGL RAITGIFEAP AFPTNNRMVT SWFPEHERAS AVGFYTSGQF
160 170 180 190 200
VGLAFLTPLL IWIQEMLSWH WVFIVTGGIG IIWSLIWFKV YQPPRLTKGI
210 220 230 240 250
SKAELDYIRD GGGLVDGDAP VKKEARQPLT AKDWKLVFHR KLIGVYLGQF
260 270 280 290 300
AVASTLWFFL TWFPNYLTQE KGITALKAGF MTTVPFLAAF VGVLLSGWVA
310 320 330 340 350
DLLVRKGFSL GFARKTPIIC GLLISTCIMG ANYTNDPMMI MCLMALAFFG
360 370 380 390 400
NGFASITWSL VSSLAPMRLI GLTGGVFNFA GGLGGITVPL VVGYLAQGYG
410 420 430
FAPALVYISA VALIGALSYI LLVGDVKRVG
Length:430
Mass (Da):47,077
Last modified:September 13, 2005 - v1
Checksum:i86B1902777F2E461
GO

Sequence cautioni

The sequence AAA62043 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L10328 Genomic DNA. Translation: AAA62043.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76714.2.
AP009048 Genomic DNA. Translation: BAE77603.1.
PIRiD65171.
RefSeqiNP_418146.4. NC_000913.3.
WP_000354284.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76714; AAC76714; b3691.
BAE77603; BAE77603; BAE77603.
GeneIDi948196.
KEGGiecj:JW5859.
eco:b3691.
PATRICi32122877. VBIEscCol129921_3814.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L10328 Genomic DNA. Translation: AAA62043.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76714.2.
AP009048 Genomic DNA. Translation: BAE77603.1.
PIRiD65171.
RefSeqiNP_418146.4. NC_000913.3.
WP_000354284.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AA76.
SMRiP0AA76. Positions 12-428.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263278. 7 interactions.
DIPiDIP-9436N.
STRINGi511145.b3691.

Protein family/group databases

TCDBi2.A.1.14.7. the major facilitator superfamily (mfs).

Proteomic databases

PaxDbiP0AA76.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76714; AAC76714; b3691.
BAE77603; BAE77603; BAE77603.
GeneIDi948196.
KEGGiecj:JW5859.
eco:b3691.
PATRICi32122877. VBIEscCol129921_3814.

Organism-specific databases

EchoBASEiEB1666.
EcoGeneiEG11715. dgoT.

Phylogenomic databases

eggNOGiENOG4105DJB. Bacteria.
ENOG410XPWC. LUCA.
HOGENOMiHOG000113642.
InParanoidiP0AA76.
KOiK08194.
OMAiIWIMALM.
PhylomeDBiP0AA76.

Enzyme and pathway databases

BioCyciEcoCyc:YIDT-MONOMER.
ECOL316407:JW5859-MONOMER.

Miscellaneous databases

PROiP0AA76.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR004744. Dgal_transporter.
IPR011701. MFS.
IPR020846. MFS_dom.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00893. 2A0114. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDGOT_ECOLI
AccessioniPrimary (citable) accession number: P0AA76
Secondary accession number(s): P31457, Q2M803
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: September 13, 2005
Last modified: September 7, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.