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Protein

Uncharacterized inner membrane transporter YedA

Gene

yedA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • transmembrane transporter activity Source: EcoCyc

GO - Biological processi

  • transmembrane transport Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:EG11141-MONOMER.
ECOL316407:JW1942-MONOMER.

Protein family/group databases

TCDBi2.A.7.3.22. the drug/metabolite transporter (dmt) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized inner membrane transporter YedA
Gene namesi
Name:yedA
Ordered Locus Names:b1959, JW1942
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11141. yedA.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 6CytoplasmicSequence analysis6
Transmembranei7 – 27HelicalSequence analysisAdd BLAST21
Topological domaini28 – 36PeriplasmicSequence analysis9
Transmembranei37 – 57HelicalSequence analysisAdd BLAST21
Topological domaini58 – 67CytoplasmicSequence analysis10
Transmembranei68 – 88HelicalSequence analysisAdd BLAST21
Topological domaini89 – 93PeriplasmicSequence analysis5
Transmembranei94 – 114HelicalSequence analysisAdd BLAST21
Topological domaini115 – 125CytoplasmicSequence analysisAdd BLAST11
Transmembranei126 – 146HelicalSequence analysisAdd BLAST21
Topological domaini147 – 148PeriplasmicSequence analysis2
Transmembranei149 – 169HelicalSequence analysisAdd BLAST21
Topological domaini170 – 173CytoplasmicSequence analysis4
Transmembranei174 – 194HelicalSequence analysisAdd BLAST21
Topological domaini195 – 206PeriplasmicSequence analysisAdd BLAST12
Transmembranei207 – 227HelicalSequence analysisAdd BLAST21
Topological domaini228 – 239CytoplasmicSequence analysisAdd BLAST12
Transmembranei240 – 260HelicalSequence analysisAdd BLAST21
Topological domaini261 – 269PeriplasmicSequence analysis9
Transmembranei270 – 290HelicalSequence analysisAdd BLAST21
Topological domaini291 – 306CytoplasmicSequence analysisAdd BLAST16

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001081661 – 306Uncharacterized inner membrane transporter YedAAdd BLAST306

Proteomic databases

PaxDbiP0AA70.
PRIDEiP0AA70.

Interactioni

Protein-protein interaction databases

BioGridi4261055. 9 interactors.
STRINGi511145.b1959.

Structurei

3D structure databases

ProteinModelPortaliP0AA70.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini18 – 141EamA 1Add BLAST124
Domaini160 – 285EamA 2Add BLAST126

Sequence similaritiesi

Belongs to the EamA transporter family.Curated
Contains 2 EamA domains.Curated

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105FDR. Bacteria.
ENOG4111I0A. LUCA.
HOGENOMiHOG000258419.
InParanoidiP0AA70.
OMAiIVYVVWG.
PhylomeDBiP0AA70.

Family and domain databases

InterProiIPR004779. CO/AA/NH_transpt.
IPR000620. EamA_dom.
[Graphical view]
PfamiPF00892. EamA. 2 hits.
[Graphical view]
TIGRFAMsiTIGR00950. 2A78. 1 hit.

Sequencei

Sequence statusi: Complete.

P0AA70-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRFRQLLPLF GALFALYIIW GSTYFVIRIG VESWPPLMMA GVRFLAAGIL
60 70 80 90 100
LLAFLLLRGH KLPPLRPLLN AALIGLLLLA VGNGMVTVAE HQNVPSGIAA
110 120 130 140 150
VVVATVPLFT LCFSRLFGIK TRKLEWVGIA IGLAGIIMLN SGGNLSGNPW
160 170 180 190 200
GAILILIGSI SWAFGSVYGS RITLPVGMMA GAIEMLAAGV VLMIASMIAG
210 220 230 240 250
EKLTALPSLS GFLAVGYLAL FGSIIAINAY MYLIRNVSPA LATSYAYVNP
260 270 280 290 300
VVAVLLGTGL GGETLSKIEW LALGVIVFAV VLVTLGKYLF PAKPVVAPVI

QDASSE
Length:306
Mass (Da):32,194
Last modified:September 13, 2005 - v1
Checksum:i6F0D63E8090ACA64
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X13330 Genomic DNA. Translation: CAA31708.1.
U00096 Genomic DNA. Translation: AAC75025.1.
AP009048 Genomic DNA. Translation: BAA15786.1.
PIRiJS0266.
RefSeqiNP_416468.1. NC_000913.3.
WP_001212226.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75025; AAC75025; b1959.
BAA15786; BAA15786; BAA15786.
GeneIDi946461.
KEGGiecj:JW1942.
eco:b1959.
PATRICi32119247. VBIEscCol129921_2038.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X13330 Genomic DNA. Translation: CAA31708.1.
U00096 Genomic DNA. Translation: AAC75025.1.
AP009048 Genomic DNA. Translation: BAA15786.1.
PIRiJS0266.
RefSeqiNP_416468.1. NC_000913.3.
WP_001212226.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0AA70.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261055. 9 interactors.
STRINGi511145.b1959.

Protein family/group databases

TCDBi2.A.7.3.22. the drug/metabolite transporter (dmt) superfamily.

Proteomic databases

PaxDbiP0AA70.
PRIDEiP0AA70.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75025; AAC75025; b1959.
BAA15786; BAA15786; BAA15786.
GeneIDi946461.
KEGGiecj:JW1942.
eco:b1959.
PATRICi32119247. VBIEscCol129921_2038.

Organism-specific databases

EchoBASEiEB1131.
EcoGeneiEG11141. yedA.

Phylogenomic databases

eggNOGiENOG4105FDR. Bacteria.
ENOG4111I0A. LUCA.
HOGENOMiHOG000258419.
InParanoidiP0AA70.
OMAiIVYVVWG.
PhylomeDBiP0AA70.

Enzyme and pathway databases

BioCyciEcoCyc:EG11141-MONOMER.
ECOL316407:JW1942-MONOMER.

Miscellaneous databases

PROiP0AA70.

Family and domain databases

InterProiIPR004779. CO/AA/NH_transpt.
IPR000620. EamA_dom.
[Graphical view]
PfamiPF00892. EamA. 2 hits.
[Graphical view]
TIGRFAMsiTIGR00950. 2A78. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYEDA_ECOLI
AccessioniPrimary (citable) accession number: P0AA70
Secondary accession number(s): P09185
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: September 13, 2005
Last modified: November 2, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.