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Protein

50S ribosomal protein L13

Gene

rplM

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.1 Publication

GO - Molecular functioni

  • large ribosomal subunit rRNA binding Source: EcoCyc
  • mRNA binding Source: GO_Central
  • structural constituent of ribosome Source: GO_Central
  • zinc ion binding Source: EcoliWiki

GO - Biological processi

  • negative regulation of translation Source: EcoCyc
  • translation Source: GO_Central

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciEcoCyc:EG10874-MONOMER
MetaCyc:EG10874-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L13UniRule annotation
Alternative name(s):
Large ribosomal subunit protein uL131 Publication
Gene namesi
Name:rplMUniRule annotation
Ordered Locus Names:b3231, JW3200
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10874 rplM

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: EcoCyc
  • cytosolic large ribosomal subunit Source: EcoCyc

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001337341 – 14250S ribosomal protein L13Add BLAST142

Proteomic databases

EPDiP0AA10
PaxDbiP0AA10
PRIDEiP0AA10

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit.9 Publications

Protein-protein interaction databases

BioGridi852140, 1 interactor
DIPiDIP-47837N
IntActiP0AA10, 122 interactors
STRINGi316385.ECDH10B_3408

Structurei

Secondary structure

1142
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi8 – 10Combined sources3
Beta strandi15 – 19Combined sources5
Helixi25 – 37Combined sources13
Turni38 – 40Combined sources3
Beta strandi53 – 57Combined sources5
Helixi59 – 61Combined sources3
Helixi68 – 71Combined sources4
Beta strandi73 – 77Combined sources5
Beta strandi84 – 88Combined sources5
Helixi89 – 95Combined sources7
Helixi98 – 108Combined sources11
Helixi113 – 120Combined sources8
Beta strandi122 – 124Combined sources3
Beta strandi126 – 128Combined sources3
Helixi132 – 135Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1ML5electron microscopy14.00m1-142[»]
2J28electron microscopy8.00J1-140[»]
2RDOelectron microscopy9.10J1-142[»]
3BBXelectron microscopy10.00J1-142[»]
3IY9electron microscopy14.10J1-140[»]
3J5Lelectron microscopy6.60J1-142[»]
3J7Zelectron microscopy3.90J1-142[»]
3J8Gelectron microscopy5.00J1-142[»]
3J9Yelectron microscopy3.90J1-142[»]
3J9Zelectron microscopy3.60LF1-142[»]
3JA1electron microscopy3.60LL1-142[»]
3JBUelectron microscopy3.64j1-142[»]
3JBVelectron microscopy3.32j1-142[»]
3JCDelectron microscopy3.70J1-142[»]
3JCEelectron microscopy3.20J1-142[»]
3JCJelectron microscopy3.70I1-142[»]
3JCNelectron microscopy4.60J1-142[»]
4CSUelectron microscopy5.50J1-142[»]
4U1UX-ray2.95BJ/DJ1-142[»]
4U1VX-ray3.00BJ/DJ1-142[»]
4U20X-ray2.90BJ/DJ1-142[»]
4U24X-ray2.90BJ/DJ1-142[»]
4U25X-ray2.90BJ/DJ1-142[»]
4U26X-ray2.80BJ/DJ1-142[»]
4U27X-ray2.80BJ/DJ1-142[»]
4UY8electron microscopy3.80J1-142[»]
4V47electron microscopy12.30AH1-142[»]
4V48electron microscopy11.50AH1-142[»]
4V4HX-ray3.46BJ/DJ1-142[»]
4V4QX-ray3.46BJ/DJ1-142[»]
4V4Velectron microscopy15.00BH1-142[»]
4V4Welectron microscopy15.00BH1-142[»]
4V50X-ray3.22BJ/DJ1-142[»]
4V52X-ray3.21BJ/DJ1-142[»]
4V53X-ray3.54BJ/DJ1-142[»]
4V54X-ray3.30BJ/DJ1-142[»]
4V55X-ray4.00BJ/DJ1-142[»]
4V56X-ray3.93BJ/DJ1-142[»]
4V57X-ray3.50BJ/DJ1-142[»]
4V5BX-ray3.74AJ/CJ1-142[»]
4V5Helectron microscopy5.80BJ1-142[»]
4V5YX-ray4.45BJ/DJ1-142[»]
4V64X-ray3.50BJ/DJ1-142[»]
4V65electron microscopy9.00B61-140[»]
4V66electron microscopy9.00B61-140[»]
4V69electron microscopy6.70BJ1-142[»]
4V6CX-ray3.19BJ/DJ1-142[»]
4V6DX-ray3.81BJ/DJ1-142[»]
4V6EX-ray3.71BJ/DJ1-142[»]
4V6Kelectron microscopy8.25AK1-142[»]
4V6Lelectron microscopy13.20BK1-142[»]
4V6Melectron microscopy7.10BJ1-142[»]
4V6Nelectron microscopy12.10AL1-142[»]
4V6Oelectron microscopy14.70BL1-142[»]
4V6Pelectron microscopy13.50BL1-142[»]
4V6Qelectron microscopy11.50BL1-142[»]
4V6Relectron microscopy11.50BL1-142[»]
4V6Selectron microscopy13.10AL1-142[»]
4V6Telectron microscopy8.30BJ1-142[»]
4V6Velectron microscopy9.80BN1-142[»]
4V6Yelectron microscopy12.00BJ1-142[»]
4V6Zelectron microscopy12.00BJ1-142[»]
4V70electron microscopy17.00BJ1-142[»]
4V71electron microscopy20.00BJ1-142[»]
4V72electron microscopy13.00BJ1-142[»]
4V73electron microscopy15.00BJ1-142[»]
4V74electron microscopy17.00BJ1-142[»]
4V75electron microscopy12.00BJ1-142[»]
4V76electron microscopy17.00BJ1-142[»]
4V77electron microscopy17.00BJ1-142[»]
4V78electron microscopy20.00BJ1-142[»]
4V79electron microscopy15.00BJ1-142[»]
4V7Aelectron microscopy9.00BJ1-142[»]
4V7Belectron microscopy6.80BJ1-142[»]
4V7Celectron microscopy7.60BL1-142[»]
4V7Delectron microscopy7.60AM1-142[»]
4V7Ielectron microscopy9.60AJ1-142[»]
4V7SX-ray3.25BJ/DJ1-142[»]
4V7TX-ray3.19BJ/DJ1-142[»]
4V7UX-ray3.10BJ/DJ1-142[»]
4V7VX-ray3.29BJ/DJ1-142[»]
4V85X-ray3.20N1-142[»]
4V89X-ray3.70BN1-142[»]
4V9CX-ray3.30BJ/DJ1-142[»]
4V9DX-ray3.00CJ/DJ1-142[»]
4V9OX-ray2.90AJ/CJ/EJ/GJ1-142[»]
4V9PX-ray2.90AJ/CJ/EJ/GJ1-142[»]
4WF1X-ray3.09BJ/DJ1-142[»]
4WOIX-ray3.00BJ/CJ1-142[»]
4WWWX-ray3.10RJ/YJ1-142[»]
4YBBX-ray2.10CK/DK1-142[»]
5ADYelectron microscopy4.50J1-142[»]
5AFIelectron microscopy2.90J1-142[»]
5AKAelectron microscopy5.70J1-142[»]
5GADelectron microscopy3.70K1-142[»]
5GAEelectron microscopy3.33K1-142[»]
5GAFelectron microscopy4.30K1-142[»]
5GAGelectron microscopy3.80K1-142[»]
5GAHelectron microscopy3.80K1-142[»]
5H5Uelectron microscopy3.00K1-142[»]
5IQRelectron microscopy3.00J1-142[»]
5IT8X-ray3.12CK/DK1-142[»]
5J5BX-ray2.80CK/DK1-142[»]
5J7LX-ray3.00CK/DK1-142[»]
5J88X-ray3.32CK/DK1-142[»]
5J8AX-ray3.10CK/DK1-142[»]
5J91X-ray2.96CK/DK1-142[»]
5JC9X-ray3.03CK/DK1-142[»]
5JTEelectron microscopy3.60BJ1-142[»]
5JU8electron microscopy3.60BJ1-142[»]
5KCRelectron microscopy3.601N1-142[»]
5KCSelectron microscopy3.901N1-142[»]
5KPSelectron microscopy3.90J1-142[»]
5KPVelectron microscopy4.10I1-142[»]
5KPWelectron microscopy3.90I1-142[»]
5KPXelectron microscopy3.90I1-142[»]
5L3Pelectron microscopy3.70N1-142[»]
5LZAelectron microscopy3.60J1-142[»]
5LZBelectron microscopy5.30J1-142[»]
5LZCelectron microscopy4.80J1-142[»]
5LZDelectron microscopy3.40J1-142[»]
5LZEelectron microscopy3.50J1-142[»]
5LZFelectron microscopy4.60J1-142[»]
5MDVelectron microscopy2.97J1-142[»]
5MDWelectron microscopy3.06J1-142[»]
5MDYelectron microscopy3.35J1-142[»]
5MDZelectron microscopy3.10J1-142[»]
5MGPelectron microscopy3.10J1-142[»]
5NCOelectron microscopy4.80K1-142[»]
5NP6electron microscopy3.60h1-142[»]
5NWYelectron microscopy2.93W1-142[»]
5O2Relectron microscopy3.40J1-142[»]
5U4Ielectron microscopy3.50K1-142[»]
5U9Felectron microscopy3.20121-142[»]
5U9Gelectron microscopy3.20121-142[»]
5UYKelectron microscopy3.90121-142[»]
5UYLelectron microscopy3.60121-142[»]
5UYMelectron microscopy3.20121-142[»]
5UYNelectron microscopy4.00121-142[»]
5UYPelectron microscopy3.90121-142[»]
5UYQelectron microscopy3.80121-142[»]
6BU8electron microscopy3.50121-142[»]
6C4Ielectron microscopy3.24K1-142[»]
6ENFelectron microscopy3.20J1-142[»]
6ENJelectron microscopy3.70J1-142[»]
6ENUelectron microscopy3.10J1-142[»]
ProteinModelPortaliP0AA10
SMRiP0AA10
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0AA10

Family & Domainsi

Sequence similaritiesi

Belongs to the universal ribosomal protein uL13 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0102 LUCA
HOGENOMiHOG000225286
InParanoidiP0AA10
KOiK02871
OMAiVLMGKHK
PhylomeDBiP0AA10

Family and domain databases

CDDicd00392 Ribosomal_L13, 1 hit
Gene3Di3.90.1180.10, 1 hit
HAMAPiMF_01366 Ribosomal_L13, 1 hit
InterProiView protein in InterPro
IPR005822 Ribosomal_L13
IPR005823 Ribosomal_L13_bac-type
IPR023563 Ribosomal_L13_CS
IPR036899 Ribosomal_L13_sf
PANTHERiPTHR11545 PTHR11545, 1 hit
PfamiView protein in Pfam
PF00572 Ribosomal_L13, 1 hit
PIRSFiPIRSF002181 Ribosomal_L13, 1 hit
SUPFAMiSSF52161 SSF52161, 1 hit
TIGRFAMsiTIGR01066 rplM_bact, 1 hit
PROSITEiView protein in PROSITE
PS00783 RIBOSOMAL_L13, 1 hit

Sequencei

Sequence statusi: Complete.

P0AA10-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTFTAKPET VKRDWYVVDA TGKTLGRLAT ELARRLRGKH KAEYTPHVDT
60 70 80 90 100
GDYIIVLNAD KVAVTGNKRT DKVYYHHTGH IGGIKQATFE EMIARRPERV
110 120 130 140
IEIAVKGMLP KGPLGRAMFR KLKVYAGNEH NHAAQQPQVL DI
Length:142
Mass (Da):16,019
Last modified:July 21, 1986 - v1
Checksum:i58B45EF9EB75FDCD
GO

Mass spectrometryi

Molecular mass is 16018.0 Da from positions 1 - 142. Determined by MALDI. 1 Publication

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X02130 Genomic DNA Translation: CAA26041.1
U18997 Genomic DNA Translation: AAA58033.1
U00096 Genomic DNA Translation: AAC76263.1
AP009048 Genomic DNA Translation: BAE77274.1
PIRiA02787 R5EC13
RefSeqiNP_417698.1, NC_000913.3
WP_000847559.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC76263; AAC76263; b3231
BAE77274; BAE77274; BAE77274
GeneIDi947828
KEGGiecj:JW3200
eco:b3231
PATRICifig|1411691.4.peg.3497

Similar proteinsi

Entry informationi

Entry nameiRL13_ECOLI
AccessioniPrimary (citable) accession number: P0AA10
Secondary accession number(s): P02410, Q2M8Y2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: July 21, 1986
Last modified: April 25, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families

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