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Protein

Cold shock protein CspA

Gene

cspA

Organism
Escherichia coli O157:H7
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Binds to and stimulates the transcription of the CCAAT-containing, cold-shock-inducible promoters of the H-NS and GyrA proteins. Binds also to the inverted repeat 5'-ATTGG-3' (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processStress response, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Cold shock protein CspA
Short name:
CSP-A
Alternative name(s):
7.4 kDa cold shock protein
CS7.4
Gene namesi
Name:cspA
Ordered Locus Names:Z4981, ECs4441
OrganismiEscherichia coli O157:H7
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000558 Componenti: Chromosome
  • UP000002519 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001002352 – 70Cold shock protein CspAAdd BLAST69

Proteomic databases

PRIDEiP0A9Y1

Expressioni

Inductioni

In response to low temperature.By similarity

Interactioni

Protein-protein interaction databases

STRINGi155864.Z4981

Structurei

3D structure databases

ProteinModelPortaliP0A9Y1
SMRiP0A9Y1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 67CSDAdd BLAST61

Phylogenomic databases

eggNOGiENOG4105VEQ Bacteria
COG1278 LUCA
HOGENOMiHOG000070674
KOiK03704
OMAiHHSAINS

Family and domain databases

CDDicd04458 CSP_CDS, 1 hit
InterProiView protein in InterPro
IPR019844 Cold-shock_CS
IPR012156 Cold_shock_CspA
IPR011129 CSD
IPR002059 CSP_DNA-bd
IPR012340 NA-bd_OB-fold
PfamiView protein in Pfam
PF00313 CSD, 1 hit
PIRSFiPIRSF002599 Cold_shock_A, 1 hit
PRINTSiPR00050 COLDSHOCK
SMARTiView protein in SMART
SM00357 CSP, 1 hit
SUPFAMiSSF50249 SSF50249, 1 hit
PROSITEiView protein in PROSITE
PS00352 CSD_1, 1 hit
PS51857 CSD_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0A9Y1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGKMTGIVK WFNADKGFGF ITPDDGSKDV FVHFSAIQND GYKSLDEGQK
60 70
VSFTIESGAK GPAAGNVTSL
Length:70
Mass (Da):7,403
Last modified:January 23, 2007 - v2
Checksum:iCED47F00BF18A49B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA Translation: AAG58705.1
BA000007 Genomic DNA Translation: BAB37864.1
PIRiA91184
E86030
RefSeqiNP_312468.1, NC_002695.1
WP_000014594.1, NZ_NOKN01000002.1

Genome annotation databases

EnsemblBacteriaiAAG58705; AAG58705; Z4981
BAB37864; BAB37864; BAB37864
GeneIDi32213729
915643
KEGGiece:Z4981
ecs:ECs4441
PATRICifig|386585.9.peg.4648

Similar proteinsi

Entry informationi

Entry nameiCSPA_ECO57
AccessioniPrimary (citable) accession number: P0A9Y1
Secondary accession number(s): P15277, P37410, Q54170
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: January 23, 2007
Last modified: April 25, 2018
This is version 79 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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