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Protein

Rod shape-determining protein MreB

Gene

mreB

Organism
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in formation of the rod shape of the cell. May act as a negative regulator of FtsI (By similarity).By similarity

GO - Biological processi

  1. cell morphogenesis Source: InterPro
  2. regulation of cell shape Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Cell shape

Names & Taxonomyi

Protein namesi
Recommended name:
Rod shape-determining protein MreB
Gene namesi
Name:mreB
Ordered Locus Names:c4006
OrganismiEscherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Taxonomic identifieri199310 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000001410: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 347347Rod shape-determining protein MreBPRO_0000062760Add
BLAST

Proteomic databases

PRIDEiP0A9X5.

Interactioni

Protein-protein interaction databases

MINTiMINT-1222179.
STRINGi199310.c4006.

Structurei

3D structure databases

ProteinModelPortaliP0A9X5.
SMRiP0A9X5. Positions 10-334.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FtsA/MreB family.Curated

Phylogenomic databases

HOGENOMiHOG000019757.
KOiK03569.
OMAiGIVCDKS.
OrthoDBiEOG66QM00.

Family and domain databases

InterProiIPR004753. MreB_Mrl.
[Graphical view]
PfamiPF06723. MreB_Mbl. 1 hit.
[Graphical view]
PRINTSiPR01652. SHAPEPROTEIN.
TIGRFAMsiTIGR00904. mreB. 1 hit.

Sequencei

Sequence statusi: Complete.

P0A9X5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLKKFRGMFS NDLSIDLGTA NTLIYVKGQG IVLNEPSVVA IRQDRAGSPK
60 70 80 90 100
SVAAVGHDAK QMLGRTPGNI AAIRPMKDGV IADFFVTEKM LQHFIKQVHS
110 120 130 140 150
NSFMRPSPRV LVCVPVGATQ VERRAIRESA QGAGAREVFL IEEPMAAAIG
160 170 180 190 200
AGLPVSEATG SMVVDIGGGT TEVAVISLNG VVYSSSVRIG GDRFDEAIIN
210 220 230 240 250
YVRRNYGSLI GEATAERIKH EIGSAYPGDE VREIEVRGRN LAEGVPRGFT
260 270 280 290 300
LNSNEILEAL QEPLTGIVSA VMVALEQCPP ELASDISERG MVLTGGGALL
310 320 330 340
RNLDRLLMEE TGIPVVVAED PLTCVARGGG KALEMIDMHG GDLFSEE
Length:347
Mass (Da):36,952
Last modified:September 13, 2005 - v1
Checksum:i1393696D8CDAEF93
GO

Sequence cautioni

The sequence AAN82446.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014075 Genomic DNA. Translation: AAN82446.1. Different initiation.
RefSeqiNP_755872.2. NC_004431.1.

Genome annotation databases

EnsemblBacteriaiAAN82446; AAN82446; c4006.
GeneIDi1040388.
KEGGiecc:c4006.
PATRICi18285784. VBIEscCol75197_3772.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014075 Genomic DNA. Translation: AAN82446.1. Different initiation.
RefSeqiNP_755872.2. NC_004431.1.

3D structure databases

ProteinModelPortaliP0A9X5.
SMRiP0A9X5. Positions 10-334.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-1222179.
STRINGi199310.c4006.

Proteomic databases

PRIDEiP0A9X5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN82446; AAN82446; c4006.
GeneIDi1040388.
KEGGiecc:c4006.
PATRICi18285784. VBIEscCol75197_3772.

Phylogenomic databases

HOGENOMiHOG000019757.
KOiK03569.
OMAiGIVCDKS.
OrthoDBiEOG66QM00.

Family and domain databases

InterProiIPR004753. MreB_Mrl.
[Graphical view]
PfamiPF06723. MreB_Mbl. 1 hit.
[Graphical view]
PRINTSiPR01652. SHAPEPROTEIN.
TIGRFAMsiTIGR00904. mreB. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CFT073 / ATCC 700928 / UPEC.

Entry informationi

Entry nameiMREB_ECOL6
AccessioniPrimary (citable) accession number: P0A9X5
Secondary accession number(s): P13519, P76678
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: September 13, 2005
Last modified: January 7, 2015
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.