P0A9W3 (YJJK_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized ABC transporter ATP-binding protein YjjK

Gene names

Name:	yjjK
Ordered Locus Names:	b4391, JW4354

Organism

Escherichia coli (strain K12)

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	555 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily. Contains 2 ABC transporter domains.

Ontologies

Keywords
Biological process	Transport
Domain	Repeat
Ligand	ATP-binding Nucleotide-binding
Technical term	Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Biological process	transport Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed Ref.5
	Chain	2 – 555	554	Uncharacterized ABC transporter ATP-binding protein YjjK		PRO_0000093191
Regions
	Domain	6 – 259	254	ABC transporter 1
	Domain	324 – 550	227	ABC transporter 2
	Nucleotide binding	39 – 46	8	ATP 1 Potential
	Nucleotide binding	356 – 363	8	ATP 2 Potential

Sequences

	Sequence		Length	Mass (Da)
	P0A9W3 [UniParc]. Last modified January 23, 2007. Version 2. Checksum: 444C7A3E2492D978	FASTA	555	62,443
	10 20 30 40 50 60 MAQFVYTMHR VGKVVPPKRH ILKNISLSFF PGAKIGVLGL NGAGKSTLLR IMAGIDKDIE 70 80 90 100 110 120 GEARPQPDIK IGYLPQEPQL NPEHTVRESI EEAVSEVVNA LKRLDEVYAL YADPDADFDK 130 140 150 160 170 180 LAAEQGRLEE IIQAHDGHNL NVQLERAADA LRLPDWDAKI ANLSGGERRR VALCRLLLEK 190 200 210 220 230 240 PDMLLLDEPT NHLDAESVAW LERFLHDFEG TVVAITHDRY FLDNVAGWIL ELDRGEGIPW 250 260 270 280 290 300 EGNYSSWLEQ KDQRLAQEAS QEAARRKSIE KELEWVRQGT KGRQSKGKAR LARFEELNST 310 320 330 340 350 360 EYQKRNETNE LFIPPGPRLG DKVLEVSNLR KSYGDRLLID DLSFSIPKGA IVGIIGPNGA 370 380 390 400 410 420 GKSTLFRMIS GQEQPDSGTI TLGETVKLAS VDQFRDSMDN SKTVWEEVSG GLDIMKIGNT 430 440 450 460 470 480 EMPSRAYVGR FNFKGVDQGK RVGELSGGER GRLHLAKLLQ VGGNMLLLDE PTNDLDIETL 490 500 510 520 530 540 RALENALLEF PGCAMVISHD RWFLDRIATH ILDYQDEGKV EFFEGNFTEY EEYKKRTLGA 550 DALEPKRIKY KRIAK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes." Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L., Blattner F.R. Nucleic Acids Res. 23:2105-2119(1995) [PubMed: 7610040] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], SEQUENCE REVISION TO C-TERMINUS. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]	"Murein-metabolizing enzymes from Escherichia coli: sequence analysis and controlled overexpression of the slt gene, which encodes the soluble lytic transglycosylase." Engel H., Kazemier B., Keck W. J. Bacteriol. 173:6773-6782(1991) [PubMed: 1938883] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-80.
[5]	"Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12." Link A.J., Robison K., Church G.M. Electrophoresis 18:1259-1313(1997) [PubMed: 9298646] [Abstract] Cited for: PROTEIN SEQUENCE OF 2-12. Strain: K12 / EMG2.
[6]	"Enrichment of low abundance proteins of Escherichia coli by hydroxyapatite chromatography." Fountoulakis M., Takacs M.-F., Berndt P., Langen H., Takacs B. Electrophoresis 20:2181-2195(1999) [PubMed: 10493123] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY. Strain: B / BL21.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U14003 Genomic DNA. Translation: AAA97287.1. Frameshift. U00096 Genomic DNA. Translation: AAC77344.1. AP009048 Genomic DNA. Translation: BAE78380.1. M69185 Genomic DNA. No translation available.
PIR	F65254.
RefSeq	NP_418808.1. NC_000913.2.
3D structure databases
ProteinModelPortal	P0A9W3.
SMR	P0A9W3. Positions 4-534.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-48138N.
IntAct	P0A9W3. 7 interactions.
MINT	MINT-1222078.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000000827; EBESCP00000000827; EBESCG00000000688. EBESCT00000016534; EBESCP00000015825; EBESCG00000015594.
GeneID	948909.
GenomeReviews	Gene locus JW4354 in contig AP009048_GR. Gene locus b4391 in contig U00096_GR.
KEGG	ecj:JW4354. eco:b4391.
PATRIC	32124400. VBIEscCol129921_4540.
Organism-specific databases
EchoBASE	EB2247.
EcoGene	EG12343. yjjK.
Phylogenomic databases
eggNOG	COG0488.
GeneTree	EBGT00050000008245.
HOGENOM	HBG758042.
OMA	KRIRYKP.
PhylomeDB	P0A9W3.
ProtClustDB	PRK11819.
Enzyme and pathway databases
BioCyc	EcoCyc:YJJK-MONOMER.
Gene expression databases
Genevestigator	P0A9W3.
Family and domain databases
InterPro	IPR022374. ABC_ATP-bd_ChvD. IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR003593. ATPase_AAA+_core. [Graphical view]
PANTHER	PTHR19211:SF37. PTHR19211:SF37. 1 hit.
Pfam	PF00005. ABC_tran. 2 hits. [Graphical view]
SMART	SM00382. AAA. 2 hits. [Graphical view]
TIGRFAMs	TIGR03719. ABC_ABC_ChvD. 1 hit.
PROSITE	PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YJJK_ECOLI

Accession

Primary (citable) accession number: P0A9W3
Secondary accession number(s): P37797, Q2M5S6

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 19, 2005
Last sequence update:	January 23, 2007
Last modified:	January 25, 2012
This is version 55 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program