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Protein

HTH-type transcriptional regulator PuuR

Gene

puuR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Represses puuA, puuD and puuP.2 Publications

Pathwayi: putrescine degradation

This protein regulates the pathway putrescine degradation, which is part of Amine and polyamine degradation.
View all proteins of this organism that are known to be involved in the pathway putrescine degradation and in Amine and polyamine degradation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi23 – 42H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

  • DNA binding Source: EcoCyc
  • sequence-specific DNA binding Source: InterPro

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciEcoCyc:EG12431-MONOMER
UniPathwayiUPA00188

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional regulator PuuR
Gene namesi
Name:puuR
Synonyms:ycjC
Ordered Locus Names:b1299, JW1292
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12431 puuR

Pathology & Biotechi

Disruption phenotypei

Cells enhance strongly the transcription of puuE.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001497311 – 185HTH-type transcriptional regulator PuuRAdd BLAST185

Proteomic databases

PaxDbiP0A9U6
PRIDEiP0A9U6

Interactioni

Protein-protein interaction databases

BioGridi4263529, 9 interactors
DIPiDIP-48257N
IntActiP0A9U6, 1 interactor
STRINGi316385.ECDH10B_1416

Structurei

3D structure databases

ProteinModelPortaliP0A9U6
SMRiP0A9U6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 66HTH cro/C1-typePROSITE-ProRule annotationAdd BLAST55

Phylogenomic databases

eggNOGiENOG4107VRI Bacteria
ENOG4111ISD LUCA
HOGENOMiHOG000263463
InParanoidiP0A9U6
KOiK14056
OMAiSAHYEST
PhylomeDBiP0A9U6

Family and domain databases

CDDicd00093 HTH_XRE, 1 hit
Gene3Di2.60.120.10, 1 hit
InterProiView protein in InterPro
IPR001387 Cro/C1-type_HTH
IPR013096 Cupin_2
IPR010982 Lambda_DNA-bd_dom_sf
IPR014710 RmlC-like_jellyroll
IPR011051 RmlC_Cupin_sf
PfamiView protein in Pfam
PF07883 Cupin_2, 1 hit
PF01381 HTH_3, 1 hit
SMARTiView protein in SMART
SM00530 HTH_XRE, 1 hit
SUPFAMiSSF47413 SSF47413, 1 hit
SSF51182 SSF51182, 1 hit
PROSITEiView protein in PROSITE
PS50943 HTH_CROC1, 1 hit

Sequencei

Sequence statusi: Complete.

P0A9U6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDEGLAPGK RLSEIRQQQG LSQRRAAELS GLTHSAISTI EQDKVSPAIS
60 70 80 90 100
TLQKLLKVYG LSLSEFFSEP EKPDEPQVVI NQDDLIEMGS QGVSMKLVHN
110 120 130 140 150
GNPNRTLAMI FETYQPGTTT GERIKHQGEE IGTVLEGEIV LTINGQDYHL
160 170 180
VAGQSYAINT GIPHSFSNTS AGICRIISAH TPTTF
Length:185
Mass (Da):20,092
Last modified:July 19, 2005 - v1
Checksum:iD7D0D3FD794A7768
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC74381.1
AP009048 Genomic DNA Translation: BAA14868.1
M38433 Genomic DNA No translation available.
PIRiF64878
RefSeqiNP_415815.1, NC_000913.3
WP_001278727.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC74381; AAC74381; b1299
BAA14868; BAA14868; BAA14868
GeneIDi945886
KEGGiecj:JW1292
eco:b1299
PATRICifig|511145.12.peg.1355

Similar proteinsi

Entry informationi

Entry nameiPUUR_ECOLI
AccessioniPrimary (citable) accession number: P0A9U6
Secondary accession number(s): P38522, P76839, P77417
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: July 19, 2005
Last modified: March 28, 2018
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways

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