P0A9U1 (YBHF_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized ABC transporter ATP-binding protein YbhF

Gene names

Name:	ybhF
Ordered Locus Names:	b0794, JW5104

Organism

Escherichia coli (strain K12)

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	578 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the ABC transporter superfamily. Contains 2 ABC transporter domains.

Ontologies

Keywords
Biological process	Transport
Domain	Repeat
Ligand	ATP-binding Nucleotide-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	transport Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity Inferred from electronic annotation. Source: InterPro protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
aceE	P0AFG8	2	EBI-547696,EBI-542683

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 578	578	Uncharacterized ABC transporter ATP-binding protein YbhF		PRO_0000093156
Regions
	Domain	6 – 237	232	ABC transporter 1
	Domain	330 – 559	230	ABC transporter 2
	Nucleotide binding	40 – 47	8	ATP 1 Potential
	Nucleotide binding	362 – 369	8	ATP 2 Potential

Sequences

	Sequence		Length	Mass (Da)
	P0A9U1 [UniParc]. Last modified July 19, 2005. Version 1. Checksum: DB3B3FA213490F3C	FASTA	578	63,132
	10 20 30 40 50 60 MNDAVITLNG LEKRFPGMDK PAVAPLDCTI HAGYVTGLVG PDGAGKTTLM RMLAGLLKPD 70 80 90 100 110 120 SGSATVIGFD PIKNDGALHA VLGYMPQKFG LYEDLTVMEN LNLYADLRSV TGEARKQTFA 130 140 150 160 170 180 RLLEFTSLGP FTGRLAGKLS GGMKQKLGLA CTLVGEPKVL LLDEPGVGVD PISRRELWQM 190 200 210 220 230 240 VHELAGEGML ILWSTSYLDE AEQCRDVLLM NEGELLYQGE PKALTQTMAG RSFLMTSPHE 250 260 270 280 290 300 GNRKLLQRAL KLPQVSDGMI QGKSVRLILK KEATPDDIRH ADGMPEININ ETTPRFEDAF 310 320 330 340 350 360 IDLLGGAGTS ESPLGAILHT VEGTPGETVI EAKELTKKFG DFAATDHVNF AVKRGEIFGL 370 380 390 400 410 420 LGPNGAGKST TFKMMCGLLV PTSGQALVLG MDLKESSGKA RQHLGYMAQK FSLYGNLTVE 430 440 450 460 470 480 QNLRFFSGVY GLRGRAQNEK ISRMSEAFGL KSIASHATDE LPLGFKQRLA LACSLMHEPD 490 500 510 520 530 540 ILFLDEPTSG VDPLTRREFW LHINSMVEKG VTVMVTTHFM DEAEYCDRIG LVYRGKLIAS 550 560 570 GTPDDLKAQS ANDEQPDPTM EQAFIQLIHD WDKEHSNE

References

[1]	"A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map." Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K., Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S., Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K. , Mori H., Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G., Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M., Horiuchi T. DNA Res. 3:137-155(1996) [PubMed: 8905232] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U00096 Genomic DNA. Translation: AAC73881.2. AP009048 Genomic DNA. Translation: BAA35454.2.
PIR	B64816.
RefSeq	NP_415315.4. NC_000913.2.
3D structure databases
ProteinModelPortal	P0A9U1.
SMR	P0A9U1. Positions 4-233, 329-568.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-48149N.
IntAct	P0A9U1. 6 interactions.
MINT	MINT-1249856.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000001661; EBESCP00000001661; EBESCG00000001372. EBESCT00000017820; EBESCP00000017111; EBESCG00000016876.
GeneID	945413.
GenomeReviews	Gene locus JW5104 in contig AP009048_GR. Gene locus b0794 in contig U00096_GR.
KEGG	ecj:JW5104. eco:b0794.
PATRIC	32116789. VBIEscCol129921_0820.
Organism-specific databases
EchoBASE	EB3098.
EcoGene	EG13314. ybhF.
Phylogenomic databases
eggNOG	COG1131.
GeneTree	EBGT00050000008244.
HOGENOM	HBG462935.
OMA	THINGLV.
PhylomeDB	P0A9U1.
ProtClustDB	CLSK879770.
Enzyme and pathway databases
BioCyc	EcoCyc:YBHF-MONOMER.
Gene expression databases
Genevestigator	P0A9U1.
Family and domain databases
InterPro	IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR003593. ATPase_AAA+_core. [Graphical view]
KO	K01990.
Pfam	PF00005. ABC_tran. 2 hits. [Graphical view]
SMART	SM00382. AAA. 2 hits. [Graphical view]
PROSITE	PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YBHF_ECOLI

Accession

Primary (citable) accession number: P0A9U1
Secondary accession number(s): P75776, Q9R7S3, Q9R7S4

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 19, 2005
Last sequence update:	July 19, 2005
Last modified:	January 25, 2012
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program