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Protein

High-affinity branched-chain amino acid transport ATP-binding protein LivG

Gene

livG

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Component of the leucine-specific transport system.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi38 – 458ATPPROSITE-ProRule annotation

GO - Molecular functioni

  • ATPase activity Source: InterPro
  • ATP binding Source: UniProtKB-KW
  • branched-chain amino acid transmembrane transporter activity Source: EcoCyc

GO - Biological processi

  • branched-chain amino acid transport Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

Amino-acid transport, Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciEcoCyc:LIVG-MONOMER.
ECOL316407:JW3420-MONOMER.
MetaCyc:LIVG-MONOMER.
RETL1328306-WGS:GSTH-5146-MONOMER.
RETL1328306-WGS:GSTH-6388-MONOMER.

Protein family/group databases

TCDBi3.A.1.4.1. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
High-affinity branched-chain amino acid transport ATP-binding protein LivG
Alternative name(s):
LIV-I protein G
Gene namesi
Name:livG
Ordered Locus Names:b3455, JW3420
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10537. livG.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 255255High-affinity branched-chain amino acid transport ATP-binding protein LivGPRO_0000092406Add
BLAST

Proteomic databases

PaxDbiP0A9S7.
PRIDEiP0A9S7.

Interactioni

Protein-protein interaction databases

BioGridi4261119. 377 interactions.
IntActiP0A9S7. 6 interactions.
STRINGi511145.b3455.

Structurei

3D structure databases

ProteinModelPortaliP0A9S7.
SMRiP0A9S7. Positions 6-254.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini6 – 254249ABC transporterPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the ABC transporter superfamily.Curated
Contains 1 ABC transporter domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105C0Z. Bacteria.
COG0411. LUCA.
InParanoidiP0A9S7.
KOiK01995.
OMAiAMERAQY.
PhylomeDBiP0A9S7.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR032823. BCA_ABC_TP_C.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00005. ABC_tran. 1 hit.
PF12399. BCA_ABC_TP_C. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0A9S7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQPLLSVNG LMMRFGGLLA VNNVNLELYP QEIVSLIGPN GAGKTTVFNC
60 70 80 90 100
LTGFYKPTGG TILLRDQHLE GLPGQQIARM GVVRTFQHVR LFREMTVIEN
110 120 130 140 150
LLVAQHQQLK TGLFSGLLKT PSFRRAQSEA LDRAATWLER IGLLEHANRQ
160 170 180 190 200
ASNLAYGDQR RLEIARCMVT QPEILMLDEP AAGLNPKETK ELDELIAELR
210 220 230 240 250
NHHNTTILLI EHDMKLVMGI SDRIYVVNQG TPLANGTPEQ IRNNPDVIRA

YLGEA
Length:255
Mass (Da):28,427
Last modified:July 19, 2005 - v1
Checksum:iD05B2F344DF7CA85
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti130 – 1301A → R in AAA83886 (PubMed:2195019).Curated
Sequence conflicti237 – 2371T → S in AAA83886 (PubMed:2195019).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J05516 Genomic DNA. Translation: AAA83886.1.
U00039 Genomic DNA. Translation: AAB18430.1.
U00096 Genomic DNA. Translation: AAC76480.1.
AP009048 Genomic DNA. Translation: BAE77838.1.
PIRiF37074.
RefSeqiNP_417912.1. NC_000913.3.
WP_000082101.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76480; AAC76480; b3455.
BAE77838; BAE77838; BAE77838.
GeneIDi947967.
KEGGiecj:JW3420.
eco:b3455.
PATRICi32122352. VBIEscCol129921_3553.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J05516 Genomic DNA. Translation: AAA83886.1.
U00039 Genomic DNA. Translation: AAB18430.1.
U00096 Genomic DNA. Translation: AAC76480.1.
AP009048 Genomic DNA. Translation: BAE77838.1.
PIRiF37074.
RefSeqiNP_417912.1. NC_000913.3.
WP_000082101.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0A9S7.
SMRiP0A9S7. Positions 6-254.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261119. 377 interactions.
IntActiP0A9S7. 6 interactions.
STRINGi511145.b3455.

Protein family/group databases

TCDBi3.A.1.4.1. the atp-binding cassette (abc) superfamily.

Proteomic databases

PaxDbiP0A9S7.
PRIDEiP0A9S7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76480; AAC76480; b3455.
BAE77838; BAE77838; BAE77838.
GeneIDi947967.
KEGGiecj:JW3420.
eco:b3455.
PATRICi32122352. VBIEscCol129921_3553.

Organism-specific databases

EchoBASEiEB0532.
EcoGeneiEG10537. livG.

Phylogenomic databases

eggNOGiENOG4105C0Z. Bacteria.
COG0411. LUCA.
InParanoidiP0A9S7.
KOiK01995.
OMAiAMERAQY.
PhylomeDBiP0A9S7.

Enzyme and pathway databases

BioCyciEcoCyc:LIVG-MONOMER.
ECOL316407:JW3420-MONOMER.
MetaCyc:LIVG-MONOMER.
RETL1328306-WGS:GSTH-5146-MONOMER.
RETL1328306-WGS:GSTH-6388-MONOMER.

Miscellaneous databases

PROiP0A9S7.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR032823. BCA_ABC_TP_C.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00005. ABC_tran. 1 hit.
PF12399. BCA_ABC_TP_C. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiLIVG_ECOLI
AccessioniPrimary (citable) accession number: P0A9S7
Secondary accession number(s): P22730, Q2M7B8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: July 19, 2005
Last modified: September 7, 2016
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.