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Protein

Ribonuclease G

Gene

rng

Organism
Escherichia coli O157:H7
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Involved in the processing of the 5'-end of 16S rRNA. Could be involved in chromosome segregation and cell division. It may be one of the components of the cytoplasmic axial filaments bundles or merely regulate the formation of this structure (By similarity).By similarity

Cofactori

Mg2+By similarityNote: Binds 1 Mg2+ ion per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi304 – 3041Magnesium; catalyticBy similarity
Metal bindingi347 – 3471Magnesium; catalyticBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

Cell cycle, Cell division

Keywords - Ligandi

Magnesium, Metal-binding

Enzyme and pathway databases

BioCyciECOL386585:GJFA-4082-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease G (EC:3.1.26.-)
Short name:
RNase G
Alternative name(s):
Cytoplasmic axial filament protein
Gene namesi
Name:rng
Synonyms:cafA
Ordered Locus Names:Z4605, ECs4119
OrganismiEscherichia coli O157:H7
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000558 Componenti: Chromosome
  • UP000002519 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 489488Ribonuclease GPRO_0000097381Add
BLAST

Interactioni

Protein-protein interaction databases

MINTiMINT-1221274.
STRINGi155864.Z4605.

Structurei

3D structure databases

ProteinModelPortaliP0A9J2.
SMRiP0A9J2. Positions 5-428.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini39 – 12890S1 motifPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the RNase E/G family. RNase G subfamily.Curated
Contains 1 S1 motif domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105C03. Bacteria.
COG1530. LUCA.
HOGENOMiHOG000258025.
KOiK08301.
OMAiHQRQVLR.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012340. NA-bd_OB-fold.
IPR019307. RNA-bd_AU-1/RNase_E/G.
IPR004659. RNase_E/G.
IPR022967. S1_dom.
IPR003029. S1_domain.
[Graphical view]
PfamiPF10150. RNase_E_G. 1 hit.
PF00575. S1. 1 hit.
[Graphical view]
SMARTiSM00316. S1. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00757. RNaseEG. 1 hit.
PROSITEiPS50126. S1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0A9J2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAELLVNVT PSETRVAYID GGILQEIHIE REARRGIVGN IYKGRVSRVL
60 70 80 90 100
PGMQAAFVDI GLDKAAFLHA SDIMPHTECV AGEEQKQFTV RDISELVRQG
110 120 130 140 150
QDLMVQVVKD PLGTKGARLT TDITLPSRYL VFMPGASHVG VSQRIESESE
160 170 180 190 200
RERLKKVVAE YCDEQGGFII RTAAEGVGEA ELASDAAYLK RVWTKVMERK
210 220 230 240 250
KRPQTRYQLY GELALAQRVL RDFADAELDR IRVDSRLTYE ALLEFTSEYI
260 270 280 290 300
PEMTSKLEHY TGRQPIFDLF DVENEIQRAL ERKVELKSGG YLIIDQTEAM
310 320 330 340 350
TTVDINTGAF VGHRNLDDTI FNTNIEATQA IARQLRLRNL GGIIIIDFID
360 370 380 390 400
MNNEDHRRRV LHSLEQALSK DRVKTSVNGF SALGLVEMTR KRTRESIEHV
410 420 430 440 450
LCNECPTCHG RGTVKTVETV CYEIMREIVR VHHAYDSDRF LVYASPAVAE
460 470 480
ALKGEESHSL AEVEIFVGKQ VKVQIEPLYN QEQFDVVMM
Length:489
Mass (Da):55,364
Last modified:January 23, 2007 - v2
Checksum:i9517B3367C455C99
GO

Sequence cautioni

The sequence AAG58374 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA. Translation: AAG58374.1. Different initiation.
BA000007 Genomic DNA. Translation: BAB37542.1.
PIRiG91143.
RefSeqiNP_312146.1. NC_002695.1.
WP_000123197.1. NZ_LPWC01000033.1.

Genome annotation databases

EnsemblBacteriaiAAG58374; AAG58374; Z4605.
BAB37542; BAB37542; BAB37542.
GeneIDi916034.
KEGGiece:Z4605.
ecs:ECs4119.
PATRICi18357764. VBIEscCol44059_4056.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA. Translation: AAG58374.1. Different initiation.
BA000007 Genomic DNA. Translation: BAB37542.1.
PIRiG91143.
RefSeqiNP_312146.1. NC_002695.1.
WP_000123197.1. NZ_LPWC01000033.1.

3D structure databases

ProteinModelPortaliP0A9J2.
SMRiP0A9J2. Positions 5-428.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-1221274.
STRINGi155864.Z4605.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG58374; AAG58374; Z4605.
BAB37542; BAB37542; BAB37542.
GeneIDi916034.
KEGGiece:Z4605.
ecs:ECs4119.
PATRICi18357764. VBIEscCol44059_4056.

Phylogenomic databases

eggNOGiENOG4105C03. Bacteria.
COG1530. LUCA.
HOGENOMiHOG000258025.
KOiK08301.
OMAiHQRQVLR.

Enzyme and pathway databases

BioCyciECOL386585:GJFA-4082-MONOMER.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012340. NA-bd_OB-fold.
IPR019307. RNA-bd_AU-1/RNase_E/G.
IPR004659. RNase_E/G.
IPR022967. S1_dom.
IPR003029. S1_domain.
[Graphical view]
PfamiPF10150. RNase_E_G. 1 hit.
PF00575. S1. 1 hit.
[Graphical view]
SMARTiSM00316. S1. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00757. RNaseEG. 1 hit.
PROSITEiPS50126. S1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRNG_ECO57
AccessioniPrimary (citable) accession number: P0A9J2
Secondary accession number(s): P25537, P76677
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: January 23, 2007
Last modified: September 7, 2016
This is version 78 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.