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Protein

Ribonuclease G

Gene

rng

Organism
Escherichia coli O157:H7
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in the processing of the 5'-end of 16S rRNA. Could be involved in chromosome segregation and cell division. It may be one of the components of the cytoplasmic axial filaments bundles or merely regulate the formation of this structure (By similarity).By similarity

Cofactori

Mg2+By similarityNote: Binds 1 Mg2+ ion per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi304Magnesium; catalyticBy similarity1
Metal bindingi347Magnesium; catalyticBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease
Biological processCell cycle, Cell division
LigandMagnesium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease G (EC:3.1.26.-)
Short name:
RNase G
Alternative name(s):
Cytoplasmic axial filament protein
Gene namesi
Name:rng
Synonyms:cafA
Ordered Locus Names:Z4605, ECs4119
OrganismiEscherichia coli O157:H7
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000558 Componenti: Chromosome
  • UP000002519 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00000973812 – 489Ribonuclease GAdd BLAST488

Proteomic databases

PRIDEiP0A9J2

Interactioni

Protein-protein interaction databases

STRINGi155864.Z4605

Structurei

3D structure databases

ProteinModelPortaliP0A9J2
SMRiP0A9J2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 128S1 motifPROSITE-ProRule annotationAdd BLAST90

Sequence similaritiesi

Belongs to the RNase E/G family. RNase G subfamily.Curated

Phylogenomic databases

eggNOGiENOG4105C03 Bacteria
COG1530 LUCA
HOGENOMiHOG000258025
KOiK08301
OMAiAFLHYHD

Family and domain databases

InterProiView protein in InterPro
IPR012340 NA-bd_OB-fold
IPR019307 RNA-bd_AU-1/RNase_E/G
IPR004659 RNase_E/G
IPR022967 S1_dom
IPR003029 S1_domain
PfamiView protein in Pfam
PF10150 RNase_E_G, 1 hit
PF00575 S1, 1 hit
SMARTiView protein in SMART
SM00316 S1, 1 hit
SUPFAMiSSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00757 RNaseEG, 1 hit
PROSITEiView protein in PROSITE
PS50126 S1, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0A9J2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAELLVNVT PSETRVAYID GGILQEIHIE REARRGIVGN IYKGRVSRVL
60 70 80 90 100
PGMQAAFVDI GLDKAAFLHA SDIMPHTECV AGEEQKQFTV RDISELVRQG
110 120 130 140 150
QDLMVQVVKD PLGTKGARLT TDITLPSRYL VFMPGASHVG VSQRIESESE
160 170 180 190 200
RERLKKVVAE YCDEQGGFII RTAAEGVGEA ELASDAAYLK RVWTKVMERK
210 220 230 240 250
KRPQTRYQLY GELALAQRVL RDFADAELDR IRVDSRLTYE ALLEFTSEYI
260 270 280 290 300
PEMTSKLEHY TGRQPIFDLF DVENEIQRAL ERKVELKSGG YLIIDQTEAM
310 320 330 340 350
TTVDINTGAF VGHRNLDDTI FNTNIEATQA IARQLRLRNL GGIIIIDFID
360 370 380 390 400
MNNEDHRRRV LHSLEQALSK DRVKTSVNGF SALGLVEMTR KRTRESIEHV
410 420 430 440 450
LCNECPTCHG RGTVKTVETV CYEIMREIVR VHHAYDSDRF LVYASPAVAE
460 470 480
ALKGEESHSL AEVEIFVGKQ VKVQIEPLYN QEQFDVVMM
Length:489
Mass (Da):55,364
Last modified:January 23, 2007 - v2
Checksum:i9517B3367C455C99
GO

Sequence cautioni

The sequence AAG58374 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA Translation: AAG58374.1 Different initiation.
BA000007 Genomic DNA Translation: BAB37542.1
PIRiG91143
RefSeqiNP_312146.1, NC_002695.1
WP_000123197.1, NZ_NOKN01000002.1

Genome annotation databases

EnsemblBacteriaiAAG58374; AAG58374; Z4605
BAB37542; BAB37542; BAB37542
GeneIDi916034
KEGGiece:Z4605
ecs:ECs4119
PATRICifig|386585.9.peg.4300

Similar proteinsi

Entry informationi

Entry nameiRNG_ECO57
AccessioniPrimary (citable) accession number: P0A9J2
Secondary accession number(s): P25537, P76677
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: January 23, 2007
Last modified: April 25, 2018
This is version 88 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health