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Protein

Transcriptional regulator MntR

Gene

mntR

Organism
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Activator, Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Manganese

Enzyme and pathway databases

BioCyciECOL199310:C0903-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional regulator MntR
Alternative name(s):
Manganese transport regulator
Gene namesi
Name:mntR
Ordered Locus Names:c0903
OrganismiEscherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Taxonomic identifieri199310 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000001410 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 155155Transcriptional regulator MntRPRO_0000201112Add
BLAST

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi199310.c0903.

Structurei

3D structure databases

ProteinModelPortaliP0A9F2.
SMRiP0A9F2. Positions 24-150.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini34 – 9562HTH dtxR-typePROSITE-ProRule annotationAdd
BLAST

Domaini

It contains an N-terminal DNA-binding domain and a metal-binding domain.By similarity

Sequence similaritiesi

Contains 1 HTH dtxR-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105KST. Bacteria.
COG1321. LUCA.
HOGENOMiHOG000040349.
KOiK11924.
OMAiCPYVLKQ.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
1.10.60.10. 1 hit.
InterProiIPR001367. Fe_dep_repressor.
IPR022687. HTH_DTXR.
IPR022689. Iron_dep_repressor.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF02742. Fe_dep_repr_C. 1 hit.
PF01325. Fe_dep_repress. 1 hit.
[Graphical view]
SMARTiSM00529. HTH_DTXR. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF47979. SSF47979. 1 hit.
PROSITEiPS50944. HTH_DTXR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0A9F2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRRAGTPTA KKVTQLVNVE EHVEGFRQVR EAHRRELIDD YVELISDLIR
60 70 80 90 100
EVGEARQVDM AARLGVSQPT VAKMLKRLAT MGLIEMIPWR GVFLTAEGEK
110 120 130 140 150
LAQESRERHQ IVENFLLVLG VSPEIARRDA EGMEHHVSEE TLDAFRLFTQ

KHGAK
Length:155
Mass (Da):17,640
Last modified:July 19, 2005 - v1
Checksum:iCB316AC7F1BDD106
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014075 Genomic DNA. Translation: AAN79376.1.
RefSeqiWP_000091016.1. NC_004431.1.

Genome annotation databases

EnsemblBacteriaiAAN79376; AAN79376; c0903.
KEGGiecc:c0903.
PATRICi18279853. VBIEscCol75197_0856.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014075 Genomic DNA. Translation: AAN79376.1.
RefSeqiWP_000091016.1. NC_004431.1.

3D structure databases

ProteinModelPortaliP0A9F2.
SMRiP0A9F2. Positions 24-150.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi199310.c0903.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN79376; AAN79376; c0903.
KEGGiecc:c0903.
PATRICi18279853. VBIEscCol75197_0856.

Phylogenomic databases

eggNOGiENOG4105KST. Bacteria.
COG1321. LUCA.
HOGENOMiHOG000040349.
KOiK11924.
OMAiCPYVLKQ.

Enzyme and pathway databases

BioCyciECOL199310:C0903-MONOMER.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
1.10.60.10. 1 hit.
InterProiIPR001367. Fe_dep_repressor.
IPR022687. HTH_DTXR.
IPR022689. Iron_dep_repressor.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF02742. Fe_dep_repr_C. 1 hit.
PF01325. Fe_dep_repress. 1 hit.
[Graphical view]
SMARTiSM00529. HTH_DTXR. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF47979. SSF47979. 1 hit.
PROSITEiPS50944. HTH_DTXR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMNTR_ECOL6
AccessioniPrimary (citable) accession number: P0A9F2
Secondary accession number(s): P75787
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: July 19, 2005
Last modified: September 7, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.