Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P0A9F0 (YEIL_ECO57) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Regulatory protein YeiL
Gene names
Name:yeiL
Ordered Locus Names:Z3420, ECs3055
OrganismEscherichia coli O157:H7 [Complete proteome] [HAMAP]
Taxonomic identifier83334 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length219 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Transcription regulator involved in mid-term, stationary-phase viability under nitrogen starvation. Might control expression of the salvage pathways or in some other way repress the recycling of nucleobases to nucleic acids and enhance their use as general nitrogen sources during nitrogen-limited growth By similarity.

Cofactor

Binds 1 4Fe-4S cluster per subunit Probable.

Subunit structure

Homodimer Probable.

Subcellular location

Cytoplasm Probable.

Sequence similarities

Contains 1 cyclic nucleotide-binding domain.

Contains 1 HTH crp-type DNA-binding domain.

Ontologies

Keywords
   Biological processTranscription
Transcription regulation
   Cellular componentCytoplasm
   Ligand4Fe-4S
DNA-binding
Iron
Iron-sulfur
Metal-binding
   Molecular functionActivator
Repressor
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processregulation of transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_function4 iron, 4 sulfur cluster binding

Inferred from electronic annotation. Source: UniProtKB-KW

DNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 219219Regulatory protein YeiL
PRO_0000100183

Regions

Domain136 – 19964HTH crp-type
DNA binding158 – 18124H-T-H motif Potential
Region19 – 9779Sensory domain Potential
Region111 – 13121Dimer interface Potential

Sites

Metal binding681Iron-sulfur (4Fe-4S) Potential
Metal binding911Iron-sulfur (4Fe-4S) Potential
Metal binding931Iron-sulfur (4Fe-4S) Potential
Metal binding1161Iron-sulfur (4Fe-4S) Potential

Sequences

Sequence LengthMass (Da)Tools
P0A9F0 [UniParc].

Last modified July 19, 2005. Version 1.
Checksum: 47720B07A9FD412D

FASTA21925,294
        10         20         30         40         50         60 
MSESAFKDCF LTDVSADTRL FHFLARDYIV QEGQQPSWLF YLTRGRARLY ATLANGRVSL 

        70         80         90        100        110        120 
IDFFAAPCFI GEIELIDKDH EPRAVQAIEE CWCLALPMKH YRPLLLNDTL FLRKLCVTLS 

       130        140        150        160        170        180 
HKNYRNIVSL TQNQSFPLVN RLAAFILLSQ EGDLYHEKHT QAAEYLGVSY RHLLYVLAQF 

       190        200        210 
IHDGLLIKSK KGYLIKNRKQ LSGLALEMDP ENKFSGMMQ 

« Hide

References

[1]"Genome sequence of enterohaemorrhagic Escherichia coli O157:H7."
Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J., Davis N.W. expand/collapse author list , Lim A., Dimalanta E.T., Potamousis K., Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A., Blattner F.R.
Nature 409:529-533(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: O157:H7 / EDL933 / ATCC 700927 / EHEC.
[2]"Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12."
Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K., Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T. expand/collapse author list , Kuhara S., Shiba T., Hattori M., Shinagawa H.
DNA Res. 8:11-22(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: O157:H7 / Sakai / RIMD 0509952 / EHEC.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE005174 Genomic DNA. Translation: AAG57301.1.
BA000007 Genomic DNA. Translation: BAB36478.1.
PIRA85855.
G91010.
RefSeqNP_288746.1. NC_002655.2.
NP_311082.2. NC_002695.1.

3D structure databases

ProteinModelPortalP0A9F0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING155864.Z3420.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAG57301; AAG57301; Z3420.
BAB36478; BAB36478; BAB36478.
GeneID916759.
957264.
KEGGece:Z3420.
ecs:ECs3055.
PATRIC18355482. VBIEscCol44059_2943.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0664.
HOGENOMHOG000094699.
KOK16326.
OMACFIGEME.
OrthoDBEOG686NMR.

Enzyme and pathway databases

BioCycECOL386585:GJFA-3004-MONOMER.
ECOO157:YEIL-MONOMER.

Family and domain databases

Gene3D2.60.120.10. 1 hit.
InterProIPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR012318. HTH_CRP_2.
IPR014710. RmlC-like_jellyroll.
[Graphical view]
PfamPF00027. cNMP_binding. 1 hit.
[Graphical view]
SMARTSM00100. cNMP. 1 hit.
[Graphical view]
SUPFAMSSF51206. SSF51206. 1 hit.
PROSITEPS50042. CNMP_BINDING_3. 1 hit.
PS51063. HTH_CRP_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameYEIL_ECO57
AccessionPrimary (citable) accession number: P0A9F0
Secondary accession number(s): P33023
Entry history
Integrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: July 19, 2005
Last modified: June 11, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families