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Protein

Regulatory protein SoxS

Gene

soxS

Organism
Escherichia coli O157:H7
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transcriptional activator of the superoxide response regulon of E.coli that includes at least 10 genes such as sodA, nfo, zwf and micF. Binds the DNA sequence 5'-GCACN7CAA-3'. It also facilitates the subsequent binding of RNA polymerase to the micF and the nfo promoters (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi24 – 43H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Regulatory protein SoxS
Gene namesi
Name:soxS
Ordered Locus Names:Z5661, ECs5044
OrganismiEscherichia coli O157:H7
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000558 Componenti: Chromosome
  • UP000002519 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001945842 – 107Regulatory protein SoxSAdd BLAST106

Interactioni

Protein-protein interaction databases

STRINGi155864.Z5661

Structurei

3D structure databases

ProteinModelPortaliP0A9E4
SMRiP0A9E4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4108W3Q Bacteria
ENOG4111IXA LUCA
HOGENOMiHOG000120762
KOiK13631
OMAiTPTAYRH

Family and domain databases

InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR018060 HTH_AraC
IPR018062 HTH_AraC-typ_CS
IPR020449 Tscrpt_reg_HTH_AraC-type
PfamiView protein in Pfam
PF12833 HTH_18, 1 hit
PRINTSiPR00032 HTHARAC
SMARTiView protein in SMART
SM00342 HTH_ARAC, 1 hit
SUPFAMiSSF46689 SSF46689, 2 hits
PROSITEiView protein in PROSITE
PS00041 HTH_ARAC_FAMILY_1, 1 hit
PS01124 HTH_ARAC_FAMILY_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0A9E4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHQKIIQDL IAWIDEHIDQ PLNIDVVAKK SGYSKWYLQR MFRTVTHQTL
60 70 80 90 100
GDYIRQRRLL LAAVELRTTE RPIFDIAMDL GYVSQQTFSR VFRRQFDRTP

SDYRHRL
Length:107
Mass (Da):12,911
Last modified:January 23, 2007 - v2
Checksum:i7341326FBAB819D6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA Translation: AAG59260.1
BA000007 Genomic DNA Translation: BAB38467.1
PIRiD91259
H86099
RefSeqiNP_313071.1, NC_002695.1
WP_000019358.1, NZ_NOKN01000002.1

Genome annotation databases

EnsemblBacteriaiAAG59260; AAG59260; Z5661
BAB38467; BAB38467; BAB38467
GeneIDi914293
KEGGiece:Z5661
ecs:ECs5044
PATRICifig|386585.9.peg.5267

Similar proteinsi

Entry informationi

Entry nameiSOXS_ECO57
AccessioniPrimary (citable) accession number: P0A9E4
Secondary accession number(s): P22539
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: January 23, 2007
Last modified: April 25, 2018
This is version 89 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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