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Protein

Cold shock-like protein CspE

Gene

cspE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • poly(A) binding Source: EcoCyc
  • RNA binding Source: EcoliWiki
  • single-stranded DNA binding Source: EcoCyc
  • transcription antitermination factor activity, RNA binding Source: EcoliWiki

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciEcoCyc:EG12179-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Cold shock-like protein CspE
Short name:
CSP-E
Gene namesi
Name:cspE
Synonyms:gicA, msmC
Ordered Locus Names:b0623, JW0618
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12179 cspE

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: EcoCyc

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00001002532 – 69Cold shock-like protein CspEAdd BLAST68

Proteomic databases

PaxDbiP0A972
PRIDEiP0A972

Interactioni

Protein-protein interaction databases

BioGridi4260642, 29 interactors
DIPiDIP-47834N
IntActiP0A972, 49 interactors
STRINGi316385.ECDH10B_0691

Structurei

3D structure databases

ProteinModelPortaliP0A972
SMRiP0A972
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 66CSDAdd BLAST61

Phylogenomic databases

eggNOGiCOG1278 LUCA
HOGENOMiHOG000070674
InParanoidiP0A972
KOiK03704
OMAiPRAKNVR
PhylomeDBiP0A972

Family and domain databases

CDDicd04458 CSP_CDS, 1 hit
InterProiView protein in InterPro
IPR019844 Cold-shock_CS
IPR012156 Cold_shock_CspA
IPR011129 CSD
IPR002059 CSP_DNA-bd
IPR012340 NA-bd_OB-fold
PfamiView protein in Pfam
PF00313 CSD, 1 hit
PIRSFiPIRSF002599 Cold_shock_A, 1 hit
PRINTSiPR00050 COLDSHOCK
SMARTiView protein in SMART
SM00357 CSP, 1 hit
SUPFAMiSSF50249 SSF50249, 1 hit
PROSITEiView protein in PROSITE
PS00352 CSD_1, 1 hit
PS51857 CSD_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0A972-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKIKGNVKW FNESKGFGFI TPEDGSKDVF VHFSAIQTNG FKTLAEGQRV
60
EFEITNGAKG PSAANVIAL
Length:69
Mass (Da):7,463
Last modified:January 23, 2007 - v2
Checksum:i1C33C920AA82405C
GO

Sequence cautioni

The sequence AAB40823 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti58A → R (Ref. 2) Curated1

Mass spectrometryi

Molecular mass is 7331 Da from positions 2 - 69. Determined by ESI. 1 Publication

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D28497 Genomic DNA Translation: BAA05856.1
L29054 Genomic DNA Translation: AAA67556.1
S83396 Genomic DNA Translation: AAN86720.1
U82598 Genomic DNA Translation: AAB40823.1 Different initiation.
U00096 Genomic DNA Translation: AAC73724.1
AP009048 Genomic DNA Translation: BAA35266.1
PIRiS49050
RefSeqiNP_415156.1, NC_000913.3
WP_000034825.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73724; AAC73724; b0623
BAA35266; BAA35266; BAA35266
GeneIDi947024
KEGGiecj:JW0618
eco:b0623
PATRICifig|1411691.4.peg.1645

Similar proteinsi

Entry informationi

Entry nameiCSPE_ECOLI
AccessioniPrimary (citable) accession number: P0A972
Secondary accession number(s): P36997, P77103, P80434
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: January 23, 2007
Last modified: March 28, 2018
This is version 101 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome
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Main funding by: National Institutes of Health