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Protein

Chemotaxis protein CheW

Gene

cheW

Organism
Shigella flexneri
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processChemotaxis

Names & Taxonomyi

Protein namesi
Recommended name:
Chemotaxis protein CheW
Gene namesi
Name:cheW
Ordered Locus Names:SF1936, S2027
OrganismiShigella flexneri
Taxonomic identifieri623 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeShigella
Proteomesi
  • UP000002673 Componenti: Chromosome
  • UP000001006 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001983481 – 167Chemotaxis protein CheWAdd BLAST167

Proteomic databases

PaxDbiP0A967.

Interactioni

Subunit structurei

An in vitro complex of CheW/CheA(L)/CheA(S) in a 1:1:1 ratio increases the autophosphorylation of CheA and is required for the binding of CheY, the phosphorylation substrate. This complex accounts for 10% of the total number of molecules (By similarity).By similarity

Structurei

3D structure databases

ProteinModelPortaliP0A967.
SMRiP0A967.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 156CheW-likePROSITE-ProRule annotationAdd BLAST141

Phylogenomic databases

eggNOGiENOG4108V3W. Bacteria.
COG0835. LUCA.
HOGENOMiHOG000254712.
KOiK03408.
OMAiCVNIMSV.

Family and domain databases

InterProiView protein in InterPro
IPR002545. CheW.
PfamiView protein in Pfam
PF01584. CheW. 1 hit.
SMARTiView protein in SMART
SM00260. CheW. 1 hit.
SUPFAMiSSF50341. SSF50341. 1 hit.
PROSITEiView protein in PROSITE
PS50851. CHEW. 1 hit.

Sequencei

Sequence statusi: Complete.

P0A967-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTGMTNVTKL ASEPSGQEFL VFTLGDEEYG IDILKVQEIR GYDQVTRIAN
60 70 80 90 100
TPAFIKGVTN LRGVIVPIVD LRIKFSQVDV DYNDNTVVIV LNLGQRVVGI
110 120 130 140 150
VVDGVSDVLS LTAEQIRPAP EFAVTLSTEY LTGLGALGDR MLILVNIEKL
160
LNSEEMALLD SAASEVA
Length:167
Mass (Da):18,084
Last modified:April 1, 1988 - v1
Checksum:i9CE642E5F4E91BFF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005674 Genomic DNA. Translation: AAN43489.1.
AE014073 Genomic DNA. Translation: AAP17319.1.
RefSeqiNP_707782.1. NC_004337.2.
WP_000147302.1. NZ_MSKF02000172.1.

Genome annotation databases

EnsemblBacteriaiAAN43489; AAN43489; SF1936.
AAP17319; AAP17319; S2027.
GeneIDi1023709.
KEGGisfl:SF1936.
sfx:S2027.
PATRICifig|198214.7.peg.2311.

Similar proteinsi

Entry informationi

Entry nameiCHEW_SHIFL
AccessioniPrimary (citable) accession number: P0A967
Secondary accession number(s): P07365
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1988
Last sequence update: April 1, 1988
Last modified: September 27, 2017
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome