P0A945 (RIMI_ECOL6) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosomal-protein-alanine acetyltransferase
EC=2.3.1.128

Alternative name(s):
Acetylating enzyme for N-terminal of ribosomal protein S18

Gene names

Name:	rimI
Ordered Locus Names:	c5453

Organism

Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) [Complete proteome] [HAMAP]

Taxonomic identifier

199310 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	148 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This enzyme acetylates the N-terminal alanine of ribosomal protein S18 By similarity.
Catalytic activity	Acetyl-CoA + ribosomal-protein L-alanine = CoA + ribosomal-protein N-acetyl-L-alanine.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the acetyltransferase family. RimI subfamily. Contains 1 N-acetyltransferase domain.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	N-terminal protein amino acid acetylation Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ribosomal-protein-alanine N-acetyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 148	148	Ribosomal-protein-alanine acetyltransferase		PRO_0000074563
Regions
	Domain	2 – 147	146	N-acetyltransferase

Sequences

	Sequence		Length	Mass (Da)
	P0A945 [UniParc]. Last modified July 19, 2005. Version 1. Checksum: 46A8412D38D42F86	FASTA	148	16,610
	10 20 30 40 50 60 MNTISSLETT DLPAAYHIEQ RAHAFPWSEK TFASNQGERY LNFQLTQNGK MAAFAITQVV 70 80 90 100 110 120 LDEATLFNIA VDPDYQRQGL GRALLEHLID ELEKRGVATL WLEVRASNAA AIALYESLGF 130 140 NEATIRRNYY PTTDGREDAI IMALPISM

References

[1]

"Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli." Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D., Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F., Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T., Donnenberg M.S., Blattner F.R. Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CFT073 / ATCC 700928 / UPEC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014075 Genomic DNA. Translation: AAN83873.1.
RefSeq	NP_757299.1. NC_004431.1.
3D structure databases
ProteinModelPortal	P0A945.
SMR	P0A945. Positions 1-148.
ModBase	Search...
Protein-protein interaction databases
STRING	199310.c5453.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAN83873; AAN83873; c5453.
GeneID	1037088.
KEGG	ecc:c5453.
PATRIC	18288542. VBIEscCol75197_5107.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000078523.
KO	K03789.
OMA	ISQIEAC.
ProtClustDB	PRK09491.
Family and domain databases
Gene3D	3.40.630.30. 1 hit.
InterPro	IPR016181. Acyl_CoA_acyltransferase. IPR000182. GNAT_dom. IPR006464. Rbsml_AcTrfase. [Graphical view]
Pfam	PF00583. Acetyltransf_1. 1 hit. [Graphical view]
SUPFAM	SSF55729. Acyl_CoA_acyltransferase. 1 hit.
TIGRFAMs	TIGR01575. rimI. 1 hit.
PROSITE	PS51186. GNAT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RIMI_ECOL6

Accession

Primary (citable) accession number: P0A945
Secondary accession number(s): P09453

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 19, 2005
Last sequence update:	July 19, 2005
Last modified:	May 1, 2013
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program