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Protein

Putative polysaccharide export protein GfcE

Gene

gfcE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

May be involved in polysaccharide transport.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Porin

Keywords - Biological processi

Ion transport, Polysaccharide transport, Sugar transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:G6504-MONOMER.
ECOL316407:JW0966-MONOMER.

Protein family/group databases

TCDBi1.B.18.3.8. the outer membrane auxiliary (oma) protein family.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative polysaccharide export protein GfcE
Alternative name(s):
Group 4 capsule protein E homolog
Gene namesi
Name:gfcE
Synonyms:yccZ
Ordered Locus Names:b0983, JW0966
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13728. gfcE.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20PROSITE-ProRule annotationAdd BLAST20
ChainiPRO_000002522621 – 379Putative polysaccharide export protein GfcEAdd BLAST359

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi21N-palmitoyl cysteinePROSITE-ProRule annotation1
Lipidationi21S-diacylglycerol cysteinePROSITE-ProRule annotation1

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PaxDbiP0A932.
PRIDEiP0A932.

Interactioni

Protein-protein interaction databases

BioGridi4261408. 162 interactors.
STRINGi511145.b0983.

Structurei

3D structure databases

ProteinModelPortaliP0A932.
SMRiP0A932.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the BexD/CtrA/VexA family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane beta strand

Phylogenomic databases

eggNOGiENOG4105DAY. Bacteria.
COG1596. LUCA.
HOGENOMiHOG000153886.
InParanoidiP0A932.
KOiK01991.
OMAiVPRNDSQ.
PhylomeDBiP0A932.

Family and domain databases

InterProiIPR003715. Poly_export.
IPR019554. Soluble_ligand-bd.
[Graphical view]
PfamiPF02563. Poly_export. 1 hit.
PF10531. SLBB. 2 hits.
[Graphical view]
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0A932-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKNIFKFSV LTLAVLSLTA CTLVPGQNLS TSNKDVIELP DNQYDLDKMV
60 70 80 90 100
NIYPVTPGLI DQLRAKPIMS QANPELEQQI ANYEYRIGIG DVLMVTVWDH
110 120 130 140 150
PELTTPAGQY RSASDTGNWV NADGAIFYPY IGRLKVAGKT LTQVRNEITA
160 170 180 190 200
RLDSVIESPQ VDVSVAAFRS QKAYVTGEVS KSGQQPITNI PLTIMDAINA
210 220 230 240 250
AGGLTADADW RNVVLTQNGV KTKVNLYALM QRGDLRQNKL LHPGDILFIP
260 270 280 290 300
RNDDLKVFVM GEVGKQSTLK MDRSGMTLAE ALGNAEGMNQ DVADATGIFV
310 320 330 340 350
IRATQNKQNG KIANIYQLNA KDASAMILGT EFQLEPYDIV YVTTAPLARW
360 370
NRVISLLVPT ISGVHDLTET SRWIQTWPN
Length:379
Mass (Da):41,741
Last modified:July 19, 2005 - v1
Checksum:i36A5F5B9E9C5E842
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74068.1.
AP009048 Genomic DNA. Translation: BAA35748.1.
PIRiE64839.
RefSeqiNP_415503.1. NC_000913.3.
WP_001295357.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74068; AAC74068; b0983.
BAA35748; BAA35748; BAA35748.
GeneIDi945586.
KEGGiecj:JW0966.
eco:b0983.
PATRICi32117189. VBIEscCol129921_1018.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC74068.1.
AP009048 Genomic DNA. Translation: BAA35748.1.
PIRiE64839.
RefSeqiNP_415503.1. NC_000913.3.
WP_001295357.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0A932.
SMRiP0A932.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261408. 162 interactors.
STRINGi511145.b0983.

Protein family/group databases

TCDBi1.B.18.3.8. the outer membrane auxiliary (oma) protein family.

Proteomic databases

PaxDbiP0A932.
PRIDEiP0A932.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74068; AAC74068; b0983.
BAA35748; BAA35748; BAA35748.
GeneIDi945586.
KEGGiecj:JW0966.
eco:b0983.
PATRICi32117189. VBIEscCol129921_1018.

Organism-specific databases

EchoBASEiEB3492.
EcoGeneiEG13728. gfcE.

Phylogenomic databases

eggNOGiENOG4105DAY. Bacteria.
COG1596. LUCA.
HOGENOMiHOG000153886.
InParanoidiP0A932.
KOiK01991.
OMAiVPRNDSQ.
PhylomeDBiP0A932.

Enzyme and pathway databases

BioCyciEcoCyc:G6504-MONOMER.
ECOL316407:JW0966-MONOMER.

Miscellaneous databases

PROiP0A932.

Family and domain databases

InterProiIPR003715. Poly_export.
IPR019554. Soluble_ligand-bd.
[Graphical view]
PfamiPF02563. Poly_export. 1 hit.
PF10531. SLBB. 2 hits.
[Graphical view]
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGFCE_ECOLI
AccessioniPrimary (citable) accession number: P0A932
Secondary accession number(s): P75881
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: July 19, 2005
Last modified: November 2, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

In E.coli K12 / MG1655 and K12 / W3110 this operon is silenced by an IS1D insertion in the promoter region.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.