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Protein

Putative polysaccharide export protein wza

Gene

wza

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Probably involved in the export of the extracellular polysaccharide colanic acid from the cell to medium.

Pathwayi: exopolysaccharide biosynthesis

This protein is involved in the pathway exopolysaccharide biosynthesis, which is part of Glycan metabolism.
View all proteins of this organism that are known to be involved in the pathway exopolysaccharide biosynthesis and in Glycan metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Porin

Keywords - Biological processi

Exopolysaccharide synthesis, Ion transport, Polysaccharide transport, Sugar transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:G7107-MONOMER.
ECOL316407:JW2047-MONOMER.
MetaCyc:G7107-MONOMER.
UniPathwayiUPA00631.

Protein family/group databases

TCDBi1.B.18.3.1. the outer membrane auxiliary (oma) protein family.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative polysaccharide export protein wza
Gene namesi
Name:wza
Ordered Locus Names:b2062, JW2047
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13566. wza.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20PROSITE-ProRule annotationAdd BLAST20
ChainiPRO_000002522221 – 379Putative polysaccharide export protein wzaAdd BLAST359

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi21N-palmitoyl cysteinePROSITE-ProRule annotation1
Lipidationi21S-diacylglycerol cysteinePROSITE-ProRule annotation1

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PaxDbiP0A930.
PRIDEiP0A930.

Interactioni

Protein-protein interaction databases

BioGridi4261254. 236 interactors.
DIPiDIP-11134N.
IntActiP0A930. 1 interactor.
STRINGi511145.b2062.

Structurei

3D structure databases

ProteinModelPortaliP0A930.
SMRiP0A930.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the BexD/CtrA/VexA family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane beta strand

Phylogenomic databases

eggNOGiENOG4105DAY. Bacteria.
COG1596. LUCA.
HOGENOMiHOG000153886.
InParanoidiP0A930.
KOiK01991.
OMAiPAGTYRT.
PhylomeDBiP0A930.

Family and domain databases

InterProiIPR003715. Poly_export.
IPR019554. Soluble_ligand-bd.
[Graphical view]
PfamiPF02563. Poly_export. 1 hit.
PF10531. SLBB. 1 hit.
[Graphical view]
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0A930-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMKSKMKLMP LLVSVTLISG CTVLPGSNMS TMGKDVIKQQ DADFDLDKMV
60 70 80 90 100
NVYPLTPRLI DQLRPRPNVA RPNMTLESEI ANYQYRVGPG DVLNVTVWDH
110 120 130 140 150
PELTTPAGQY RSSSDTGNWV QPDGTMFYPY IGKVHVVGKT LAEIRSDITG
160 170 180 190 200
RLATYIADPQ VDVNIAAFRS QKAYISGQVN KSGQQAITNV PLTILDAINA
210 220 230 240 250
AGGLTDTADW RNVVLTHNGR EERISLQALM QNGDLNQNRL LYPGDILYVP
260 270 280 290 300
RNDDLKVFVM GEVKKQSTLK MDFSGMTLTE ALGNAEGIDM TTSNASGIFV
310 320 330 340 350
IRPLKGEGGR NGKIANIYQL DMSDATSLVM ATEFRLQPYD VVYVTTAPVS
360 370
RWNRLINQLL PTISGVRYMT DTASDIHNW
Length:379
Mass (Da):41,910
Last modified:July 19, 2005 - v1
Checksum:iC4902C8650B69B65
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti106P → R (PubMed:8763957).Curated1
Sequence conflicti106P → R (PubMed:8759852).Curated1
Sequence conflicti158D → G (PubMed:8759852).Curated1
Sequence conflicti160Q → A (PubMed:8759852).Curated1
Sequence conflicti321D → G in AAC77833 (PubMed:8759852).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75123.1.
AP009048 Genomic DNA. Translation: BAE76576.1.
U52666 Genomic DNA. Translation: AAC44334.1.
U38473 Genomic DNA. Translation: AAC77833.1.
PIRiE64972.
RefSeqiNP_416566.1. NC_000913.3.
WP_000978094.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75123; AAC75123; b2062.
BAE76576; BAE76576; BAE76576.
GeneIDi946558.
KEGGiecj:JW2047.
eco:b2062.
PATRICi32119457. VBIEscCol129921_2139.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75123.1.
AP009048 Genomic DNA. Translation: BAE76576.1.
U52666 Genomic DNA. Translation: AAC44334.1.
U38473 Genomic DNA. Translation: AAC77833.1.
PIRiE64972.
RefSeqiNP_416566.1. NC_000913.3.
WP_000978094.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0A930.
SMRiP0A930.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261254. 236 interactors.
DIPiDIP-11134N.
IntActiP0A930. 1 interactor.
STRINGi511145.b2062.

Protein family/group databases

TCDBi1.B.18.3.1. the outer membrane auxiliary (oma) protein family.

Proteomic databases

PaxDbiP0A930.
PRIDEiP0A930.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75123; AAC75123; b2062.
BAE76576; BAE76576; BAE76576.
GeneIDi946558.
KEGGiecj:JW2047.
eco:b2062.
PATRICi32119457. VBIEscCol129921_2139.

Organism-specific databases

EchoBASEiEB3336.
EcoGeneiEG13566. wza.

Phylogenomic databases

eggNOGiENOG4105DAY. Bacteria.
COG1596. LUCA.
HOGENOMiHOG000153886.
InParanoidiP0A930.
KOiK01991.
OMAiPAGTYRT.
PhylomeDBiP0A930.

Enzyme and pathway databases

UniPathwayiUPA00631.
BioCyciEcoCyc:G7107-MONOMER.
ECOL316407:JW2047-MONOMER.
MetaCyc:G7107-MONOMER.

Miscellaneous databases

PROiP0A930.

Family and domain databases

InterProiIPR003715. Poly_export.
IPR019554. Soluble_ligand-bd.
[Graphical view]
PfamiPF02563. Poly_export. 1 hit.
PF10531. SLBB. 1 hit.
[Graphical view]
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiWZA_ECOLI
AccessioniPrimary (citable) accession number: P0A930
Secondary accession number(s): P71235
, P71273, P76388, Q2MAY0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: July 19, 2005
Last modified: November 2, 2016
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.