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Protein

Outer membrane protein X

Gene

ompX

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:EG12117-MONOMER

Protein family/group databases

TCDBi1.B.6.2.1 the ompa-ompf porin (oop) family

Names & Taxonomyi

Protein namesi
Recommended name:
Outer membrane protein X
Gene namesi
Name:ompX
Synonyms:ybiG
Ordered Locus Names:b0814, JW0799
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12135 ompX

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini24 – 25Periplasmic2
Transmembranei26 – 35Beta stranded10
Topological domaini36 – 44Extracellular9
Transmembranei45 – 54Beta stranded10
Topological domaini55 – 59Periplasmic5
Transmembranei60 – 69Beta stranded10
Topological domaini70 – 85ExtracellularAdd BLAST16
Transmembranei86 – 95Beta stranded10
Topological domaini96 – 99Periplasmic4
Transmembranei100 – 109Beta stranded10
Topological domaini110 – 129ExtracellularAdd BLAST20
Transmembranei130 – 139Beta stranded10
Topological domaini140 – 143Periplasmic4
Transmembranei144 – 153Beta stranded10
Topological domaini154 – 160Extracellular7
Transmembranei161 – 170Beta stranded10
Topological domaini171Periplasmic1

GO - Cellular componenti

Keywords - Cellular componenti

Cell outer membrane, Membrane

Pathology & Biotechi

Chemistry databases

DrugBankiDB04233 (Hydroxyethyloxy)Tri(Ethyloxy)Octane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 231 PublicationAdd BLAST23
ChainiPRO_000002019924 – 171Outer membrane protein XAdd BLAST148

Proteomic databases

EPDiP0A917
PaxDbiP0A917
PRIDEiP0A917

2D gel databases

SWISS-2DPAGEP0A917

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
skpP0AEU72EBI-552413,EBI-548242

Protein-protein interaction databases

BioGridi4261010, 284 interactors
DIPiDIP-48016N
IntActiP0A917, 3 interactors
MINTiP0A917
STRINGi316385.ECDH10B_0882

Structurei

Secondary structure

1171
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi25 – 37Combined sources13
Turni38 – 40Combined sources3
Beta strandi41 – 54Combined sources14
Beta strandi55 – 57Combined sources3
Beta strandi59 – 74Combined sources16
Beta strandi75 – 77Combined sources3
Beta strandi80 – 97Combined sources18
Beta strandi100 – 117Combined sources18
Turni118 – 120Combined sources3
Beta strandi121 – 138Combined sources18
Beta strandi141 – 143Combined sources3
Beta strandi144 – 155Combined sources12
Beta strandi158 – 170Combined sources13

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1ORMNMR-A24-171[»]
1Q9FNMR-A24-171[»]
1Q9GNMR-A24-171[»]
1QJ8X-ray1.90A24-171[»]
1QJ9X-ray2.10A24-171[»]
2M06NMR-A24-171[»]
2M07NMR-A24-171[»]
2MNHNMR-A24-171[»]
ProteinModelPortaliP0A917
SMRiP0A917
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0A917

Family & Domainsi

Sequence similaritiesi

Belongs to the Ail/OmpX/PagC/Lom family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane beta strand

Phylogenomic databases

eggNOGiENOG4108T1M Bacteria
COG3637 LUCA
HOGENOMiHOG000118160
KOiK11934
OMAiKYRYEFD

Family and domain databases

InterProiView protein in InterPro
IPR000758 Enterovir_OMP
IPR011250 OMP/PagP_b-brl
IPR027385 OMP_b-brl
PfamiView protein in Pfam
PF13505 OMP_b-brl, 1 hit
PRINTSiPR00316 ENTEROVIROMP
SUPFAMiSSF56925 SSF56925, 1 hit
PROSITEiView protein in PROSITE
PS00694 ENT_VIR_OMP_1, 1 hit
PS00695 ENT_VIR_OMP_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0A917-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKIACLSAL AAVLAFTAGT SVAATSTVTG GYAQSDAQGQ MNKMGGFNLK
60 70 80 90 100
YRYEEDNSPL GVIGSFTYTE KSRTASSGDY NKNQYYGITA GPAYRINDWA
110 120 130 140 150
SIYGVVGVGY GKFQTTEYPT YKHDTSDYGF SYGAGLQFNP MENVALDFSY
160 170
EQSRIRSVDV GTWIAGVGYR F
Length:171
Mass (Da):18,603
Last modified:July 19, 2005 - v1
Checksum:i77CE1245DAE81462
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti10L → M in AAA21856 (PubMed:8021175).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L37088 Genomic DNA Translation: AAA66329.1
U00096 Genomic DNA Translation: AAC73901.1
AP009048 Genomic DNA Translation: BAA35486.1
U04242 Genomic DNA Translation: AAA21856.1
PIRiI55173
RefSeqiNP_415335.1, NC_000913.3
WP_001295296.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73901; AAC73901; b0814
BAA35486; BAA35486; BAA35486
GeneIDi944967
KEGGiecj:JW0799
eco:b0814
PATRICifig|1411691.4.peg.1464

Similar proteinsi

Entry informationi

Entry nameiOMPX_ECOLI
AccessioniPrimary (citable) accession number: P0A917
Secondary accession number(s): P36546
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: July 19, 2005
Last modified: March 28, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome
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Main funding by: National Institutes of Health