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Protein

Outer membrane protein X

Gene

ompX

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:EG12117-MONOMER.
ECOL316407:JW0799-MONOMER.

Protein family/group databases

TCDBi1.B.6.2.1. the ompa-ompf porin (oop) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Outer membrane protein X
Gene namesi
Name:ompX
Synonyms:ybiG
Ordered Locus Names:b0814, JW0799
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12135. ompX.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini24 – 25Periplasmic2
Transmembranei26 – 35Beta stranded10
Topological domaini36 – 44Extracellular9
Transmembranei45 – 54Beta stranded10
Topological domaini55 – 59Periplasmic5
Transmembranei60 – 69Beta stranded10
Topological domaini70 – 85ExtracellularAdd BLAST16
Transmembranei86 – 95Beta stranded10
Topological domaini96 – 99Periplasmic4
Transmembranei100 – 109Beta stranded10
Topological domaini110 – 129ExtracellularAdd BLAST20
Transmembranei130 – 139Beta stranded10
Topological domaini140 – 143Periplasmic4
Transmembranei144 – 153Beta stranded10
Topological domaini154 – 160Extracellular7
Transmembranei161 – 170Beta stranded10
Topological domaini171Periplasmic1

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 231 PublicationAdd BLAST23
ChainiPRO_000002019924 – 171Outer membrane protein XAdd BLAST148

Proteomic databases

EPDiP0A917.
PaxDbiP0A917.
PRIDEiP0A917.

2D gel databases

SWISS-2DPAGEP0A917.

Interactioni

Protein-protein interaction databases

BioGridi4261010. 282 interactors.
DIPiDIP-48016N.
IntActiP0A917. 2 interactors.
MINTiMINT-1256834.
STRINGi511145.b0814.

Structurei

Secondary structure

1171
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi25 – 37Combined sources13
Turni38 – 40Combined sources3
Beta strandi41 – 54Combined sources14
Beta strandi55 – 57Combined sources3
Beta strandi59 – 74Combined sources16
Beta strandi75 – 77Combined sources3
Beta strandi80 – 97Combined sources18
Beta strandi100 – 117Combined sources18
Turni118 – 120Combined sources3
Beta strandi121 – 138Combined sources18
Beta strandi141 – 143Combined sources3
Beta strandi144 – 155Combined sources12
Beta strandi158 – 170Combined sources13

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1ORMNMR-A24-171[»]
1Q9FNMR-A24-171[»]
1Q9GNMR-A24-171[»]
1QJ8X-ray1.90A24-171[»]
1QJ9X-ray2.10A24-171[»]
2M06NMR-A24-171[»]
2M07NMR-A24-171[»]
2MNHNMR-A24-171[»]
ProteinModelPortaliP0A917.
SMRiP0A917.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0A917.

Family & Domainsi

Sequence similaritiesi

Belongs to the Ail/OmpX/PagC/Lom family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane beta strand

Phylogenomic databases

eggNOGiENOG4108T1M. Bacteria.
COG3637. LUCA.
HOGENOMiHOG000118160.
KOiK11934.
OMAiKYRYEFD.

Family and domain databases

Gene3Di2.40.160.20. 1 hit.
InterProiIPR000758. Enterovir_OMP.
IPR011250. OMP/PagP_b-brl.
IPR027385. OMP_b-brl.
[Graphical view]
PfamiPF13505. OMP_b-brl. 1 hit.
[Graphical view]
PRINTSiPR00316. ENTEROVIROMP.
SUPFAMiSSF56925. SSF56925. 1 hit.
PROSITEiPS00694. ENT_VIR_OMP_1. 1 hit.
PS00695. ENT_VIR_OMP_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0A917-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKIACLSAL AAVLAFTAGT SVAATSTVTG GYAQSDAQGQ MNKMGGFNLK
60 70 80 90 100
YRYEEDNSPL GVIGSFTYTE KSRTASSGDY NKNQYYGITA GPAYRINDWA
110 120 130 140 150
SIYGVVGVGY GKFQTTEYPT YKHDTSDYGF SYGAGLQFNP MENVALDFSY
160 170
EQSRIRSVDV GTWIAGVGYR F
Length:171
Mass (Da):18,603
Last modified:July 19, 2005 - v1
Checksum:i77CE1245DAE81462
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti10L → M in AAA21856 (PubMed:8021175).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L37088 Genomic DNA. Translation: AAA66329.1.
U00096 Genomic DNA. Translation: AAC73901.1.
AP009048 Genomic DNA. Translation: BAA35486.1.
U04242 Genomic DNA. Translation: AAA21856.1.
PIRiI55173.
RefSeqiNP_415335.1. NC_000913.3.
WP_001295296.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73901; AAC73901; b0814.
BAA35486; BAA35486; BAA35486.
GeneIDi944967.
KEGGiecj:JW0799.
eco:b0814.
PATRICi32116831. VBIEscCol129921_0841.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L37088 Genomic DNA. Translation: AAA66329.1.
U00096 Genomic DNA. Translation: AAC73901.1.
AP009048 Genomic DNA. Translation: BAA35486.1.
U04242 Genomic DNA. Translation: AAA21856.1.
PIRiI55173.
RefSeqiNP_415335.1. NC_000913.3.
WP_001295296.1. NZ_LN832404.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1ORMNMR-A24-171[»]
1Q9FNMR-A24-171[»]
1Q9GNMR-A24-171[»]
1QJ8X-ray1.90A24-171[»]
1QJ9X-ray2.10A24-171[»]
2M06NMR-A24-171[»]
2M07NMR-A24-171[»]
2MNHNMR-A24-171[»]
ProteinModelPortaliP0A917.
SMRiP0A917.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261010. 282 interactors.
DIPiDIP-48016N.
IntActiP0A917. 2 interactors.
MINTiMINT-1256834.
STRINGi511145.b0814.

Protein family/group databases

TCDBi1.B.6.2.1. the ompa-ompf porin (oop) family.

2D gel databases

SWISS-2DPAGEP0A917.

Proteomic databases

EPDiP0A917.
PaxDbiP0A917.
PRIDEiP0A917.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73901; AAC73901; b0814.
BAA35486; BAA35486; BAA35486.
GeneIDi944967.
KEGGiecj:JW0799.
eco:b0814.
PATRICi32116831. VBIEscCol129921_0841.

Organism-specific databases

EchoBASEiEB2056.
EcoGeneiEG12135. ompX.

Phylogenomic databases

eggNOGiENOG4108T1M. Bacteria.
COG3637. LUCA.
HOGENOMiHOG000118160.
KOiK11934.
OMAiKYRYEFD.

Enzyme and pathway databases

BioCyciEcoCyc:EG12117-MONOMER.
ECOL316407:JW0799-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP0A917.
PROiP0A917.

Family and domain databases

Gene3Di2.40.160.20. 1 hit.
InterProiIPR000758. Enterovir_OMP.
IPR011250. OMP/PagP_b-brl.
IPR027385. OMP_b-brl.
[Graphical view]
PfamiPF13505. OMP_b-brl. 1 hit.
[Graphical view]
PRINTSiPR00316. ENTEROVIROMP.
SUPFAMiSSF56925. SSF56925. 1 hit.
PROSITEiPS00694. ENT_VIR_OMP_1. 1 hit.
PS00695. ENT_VIR_OMP_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiOMPX_ECOLI
AccessioniPrimary (citable) accession number: P0A917
Secondary accession number(s): P36546
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: July 19, 2005
Last modified: November 2, 2016
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.