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Protein

UPF0294 protein YafD

Gene

yafD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:EG11650-MONOMER.
ECOL316407:JW5017-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0294 protein YafD
Gene namesi
Name:yafD
Ordered Locus Names:b0209, JW5017
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11650. yafD.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 266266UPF0294 protein YafDPRO_0000074637Add
BLAST

Proteomic databases

PaxDbiP0A8U2.
PRIDEiP0A8U2.

Interactioni

Protein-protein interaction databases

BioGridi4261255. 228 interactions.
DIPiDIP-47877N.
STRINGi511145.b0209.

Structurei

3D structure databases

ProteinModelPortaliP0A8U2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0294 family.Curated

Phylogenomic databases

eggNOGiENOG4107NA1. Bacteria.
COG3021. LUCA.
HOGENOMiHOG000275410.
InParanoidiP0A8U2.
OMAiCCPLREK.
PhylomeDBiP0A8U2.

Family and domain databases

Gene3Di3.60.10.10. 1 hit.
HAMAPiMF_01119. UPF0294. 1 hit.
InterProiIPR005135. Endo/exonuclease/phosphatase.
IPR022958. UPF0294.
[Graphical view]
PfamiPF03372. Exo_endo_phos. 1 hit.
[Graphical view]
SUPFAMiSSF56219. SSF56219. 1 hit.

Sequencei

Sequence statusi: Complete.

P0A8U2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRKNTYAMRY VAGQPAERIL PPGSFASIGQ ALPPGEPLST EERIRILVWN
60 70 80 90 100
IYKQQRAEWL SVLKNYGKDA HLVLLQEAQT TPELVQFATA NYLAADQVPA
110 120 130 140 150
FVLPQHPSGV MTLSAAHPVY CCPLREREPI LRLAKSALVT VYPLPDTRLL
160 170 180 190 200
MVVNIHAVNF SLGVDVYSKQ LLPIGDQIAH HSGPVIMAGD FNAWSRRRMN
210 220 230 240 250
ALYRFAREMS LRQVRFTDDQ RRRAFGRPLD FVFYRGLNVS EASVLVTRAS
260
DHNPLLVEFS PGKPDK
Length:266
Mass (Da):29,992
Last modified:June 7, 2005 - v1
Checksum:i5F5AD2B0C4CE5794
GO

Sequence cautioni

The sequence AAB08631 differs from that shown. Reason: Erroneous initiation. Curated
The sequence BAA02172 differs from that shown. Reason: Erroneous initiation. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti112 – 1121T → S (PubMed:1663890).Curated
Sequence conflicti223 – 2231R → G (PubMed:1663890).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D12650 Genomic DNA. Translation: BAA02172.1. Different initiation.
U70214 Genomic DNA. Translation: AAB08631.1. Different initiation.
U00096 Genomic DNA. Translation: AAC73314.1.
AP009048 Genomic DNA. Translation: BAA77880.2.
X60739 Genomic DNA. No translation available.
PIRiC64745.
RefSeqiNP_414745.1. NC_000913.3.
WP_001230983.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73314; AAC73314; b0209.
BAA77880; BAA77880; BAA77880.
GeneIDi946286.
KEGGiecj:JW5017.
eco:b0209.
PATRICi32115531. VBIEscCol129921_0211.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D12650 Genomic DNA. Translation: BAA02172.1. Different initiation.
U70214 Genomic DNA. Translation: AAB08631.1. Different initiation.
U00096 Genomic DNA. Translation: AAC73314.1.
AP009048 Genomic DNA. Translation: BAA77880.2.
X60739 Genomic DNA. No translation available.
PIRiC64745.
RefSeqiNP_414745.1. NC_000913.3.
WP_001230983.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0A8U2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261255. 228 interactions.
DIPiDIP-47877N.
STRINGi511145.b0209.

Proteomic databases

PaxDbiP0A8U2.
PRIDEiP0A8U2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73314; AAC73314; b0209.
BAA77880; BAA77880; BAA77880.
GeneIDi946286.
KEGGiecj:JW5017.
eco:b0209.
PATRICi32115531. VBIEscCol129921_0211.

Organism-specific databases

EchoBASEiEB1603.
EcoGeneiEG11650. yafD.

Phylogenomic databases

eggNOGiENOG4107NA1. Bacteria.
COG3021. LUCA.
HOGENOMiHOG000275410.
InParanoidiP0A8U2.
OMAiCCPLREK.
PhylomeDBiP0A8U2.

Enzyme and pathway databases

BioCyciEcoCyc:EG11650-MONOMER.
ECOL316407:JW5017-MONOMER.

Miscellaneous databases

PROiP0A8U2.

Family and domain databases

Gene3Di3.60.10.10. 1 hit.
HAMAPiMF_01119. UPF0294. 1 hit.
InterProiIPR005135. Endo/exonuclease/phosphatase.
IPR022958. UPF0294.
[Graphical view]
PfamiPF03372. Exo_endo_phos. 1 hit.
[Graphical view]
SUPFAMiSSF56219. SSF56219. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYAFD_ECOLI
AccessioniPrimary (citable) accession number: P0A8U2
Secondary accession number(s): P30865, P75671
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: June 7, 2005
Last modified: September 7, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.