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Protein

Protein Syd

Gene

syd

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.

GO - Biological processi

  • regulation of protein complex assembly Source: EcoCyc

Enzyme and pathway databases

BioCyciEcoCyc:G7451-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein Syd
Gene namesi
Name:syd
Synonyms:ydr
Ordered Locus Names:b2793, JW2764
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12959. syd.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: EcoCyc
  • extrinsic component of cytoplasmic side of plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002141361 – 181Protein SydAdd BLAST181

Proteomic databases

PaxDbiP0A8U0.
PRIDEiP0A8U0.

Interactioni

Protein-protein interaction databases

BioGridi4263497. 21 interactors.
DIPiDIP-48106N.
STRINGi316385.ECDH10B_2962.

Structurei

Secondary structure

1181
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi4 – 24Combined sources21
Beta strandi25 – 27Combined sources3
Beta strandi29 – 31Combined sources3
Turni32 – 35Combined sources4
Beta strandi41 – 44Combined sources4
Beta strandi49 – 51Combined sources3
Helixi63 – 68Combined sources6
Helixi75 – 80Combined sources6
Beta strandi82 – 85Combined sources4
Beta strandi89 – 93Combined sources5
Beta strandi96 – 100Combined sources5
Helixi106 – 125Combined sources20
Beta strandi131 – 136Combined sources6
Beta strandi142 – 147Combined sources6
Turni148 – 150Combined sources3
Beta strandi153 – 157Combined sources5
Beta strandi163 – 169Combined sources7
Helixi170 – 176Combined sources7

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3FFVX-ray2.00A/B1-181[»]
ProteinModelPortaliP0A8U0.
SMRiP0A8U0.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0A8U0.

Family & Domainsi

Sequence similaritiesi

Belongs to the Syd family.Curated

Phylogenomic databases

eggNOGiENOG4108T6E. Bacteria.
ENOG4111WE9. LUCA.
HOGENOMiHOG000218409.
KOiK15723.

Family and domain databases

CDDicd16323. Syd. 1 hit.
HAMAPiMF_01104. Syd. 1 hit.
InterProiView protein in InterPro
IPR009948. Syd.
PfamiView protein in Pfam
PF07348. Syd. 1 hit.

Sequencei

Sequence statusi: Complete.

P0A8U0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDDLTAQALK DFTARYCDAW HEEHKSWPLS EELYGVPSPC IISTTEDAVY
60 70 80 90 100
WQPQPFTGEQ NVNAVERAFD IVIQPTIHTF YTTQFAGDMH AQFGDIKLTL
110 120 130 140 150
LQTWSEDDFR RVQENLIGHL VTQKRLKLPP TLFIATLEEE LEVISVCNLS
160 170 180
GEVCKETLGT RKRTHLASNL AEFLNQLKPL L
Length:181
Mass (Da):20,708
Last modified:June 7, 2005 - v1
Checksum:i95F6490B168DC222
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D38520 Genomic DNA. Translation: BAA07525.1.
U29581 Genomic DNA. Translation: AAB40443.1.
U00096 Genomic DNA. Translation: AAC75835.1.
AP009048 Genomic DNA. Translation: BAE76865.1.
PIRiA55944.
RefSeqiNP_417273.1. NC_000913.3.
WP_000342431.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75835; AAC75835; b2793.
BAE76865; BAE76865; BAE76865.
GeneIDi947271.
KEGGiecj:JW2764.
eco:b2793.
PATRICifig|1411691.4.peg.3940.

Similar proteinsi

Entry informationi

Entry nameiSYDP_ECOLI
AccessioniPrimary (citable) accession number: P0A8U0
Secondary accession number(s): P43526, Q2MA41
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: June 7, 2005
Last modified: August 30, 2017
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families