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Protein

Universal stress protein B

Gene

uspB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • response to ethanol Source: EcoCyc
  • response to stress Source: UniProtKB-HAMAP
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:EG12231-MONOMER.
ECOL316407:JW3461-MONOMER.

Protein family/group databases

TCDBi9.B.4.1.1. the universal stress protein-b (uspb) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Universal stress protein B
Gene namesi
Name:uspB
Synonyms:yhiO
Ordered Locus Names:b3494, JW3461
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12231. uspB.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei1 – 2121HelicalSequence analysisAdd
BLAST
Topological domaini22 – 8968CytoplasmicSequence analysisAdd
BLAST
Transmembranei90 – 11021HelicalSequence analysisAdd
BLAST
Topological domaini111 – 1111PeriplasmicSequence analysis

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

Pathology & Biotechi

Disruption phenotypei

Cells are sensitive to exposure to ethanol but not heat in stationary phase.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 111111Universal stress protein BPRO_0000212040Add
BLAST

Proteomic databases

PaxDbiP0A8S5.

Expressioni

Inductioni

By growth arrest in general, by carbon, phosphate, and nitrogen starvation as well as osmotic shock and oxidative stress.

Interactioni

Protein-protein interaction databases

BioGridi4262095. 12 interactions.
STRINGi511145.b3494.

Structurei

3D structure databases

ProteinModelPortaliP0A8S5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the universal stress protein B family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108V6B. Bacteria.
ENOG4111J5S. LUCA.
HOGENOMiHOG000218234.
KOiK06144.
OMAiGGFFTAH.

Family and domain databases

HAMAPiMF_01088. UspB. 1 hit.
InterProiIPR019598. Universal_stress_protein_B.
[Graphical view]
PfamiPF10625. UspB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0A8S5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MISTVALFWA LCVVCIVNMA RYFSSLRALL VVLRNCDPLL YQYVDGGGFF
60 70 80 90 100
TSHGQPNKQV RLVWYIYAQR YRDHHDDEFI RRCERVRRQF ILTSALCGLV
110
VVSLIALMIW H
Length:111
Mass (Da):13,027
Last modified:June 7, 2005 - v1
Checksum:iBFD3813EDDD9CBFB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00039 Genomic DNA. Translation: AAB18470.1.
U00096 Genomic DNA. Translation: AAC76519.1.
AP009048 Genomic DNA. Translation: BAE77800.1.
PIRiS47714.
RefSeqiNP_417951.1. NC_000913.3.
WP_000626187.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76519; AAC76519; b3494.
BAE77800; BAE77800; BAE77800.
GeneIDi948008.
KEGGiecj:JW3461.
eco:b3494.
PATRICi32122438. VBIEscCol129921_3596.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00039 Genomic DNA. Translation: AAB18470.1.
U00096 Genomic DNA. Translation: AAC76519.1.
AP009048 Genomic DNA. Translation: BAE77800.1.
PIRiS47714.
RefSeqiNP_417951.1. NC_000913.3.
WP_000626187.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0A8S5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262095. 12 interactions.
STRINGi511145.b3494.

Protein family/group databases

TCDBi9.B.4.1.1. the universal stress protein-b (uspb) family.

Proteomic databases

PaxDbiP0A8S5.

Protocols and materials databases

DNASUi948008.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76519; AAC76519; b3494.
BAE77800; BAE77800; BAE77800.
GeneIDi948008.
KEGGiecj:JW3461.
eco:b3494.
PATRICi32122438. VBIEscCol129921_3596.

Organism-specific databases

EchoBASEiEB2143.
EcoGeneiEG12231. uspB.

Phylogenomic databases

eggNOGiENOG4108V6B. Bacteria.
ENOG4111J5S. LUCA.
HOGENOMiHOG000218234.
KOiK06144.
OMAiGGFFTAH.

Enzyme and pathway databases

BioCyciEcoCyc:EG12231-MONOMER.
ECOL316407:JW3461-MONOMER.

Miscellaneous databases

PROiP0A8S5.

Family and domain databases

HAMAPiMF_01088. UspB. 1 hit.
InterProiIPR019598. Universal_stress_protein_B.
[Graphical view]
PfamiPF10625. UspB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiUSPB_ECOLI
AccessioniPrimary (citable) accession number: P0A8S5
Secondary accession number(s): P37632, Q2M7F6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: June 7, 2005
Last modified: September 7, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

Overexpression of uspB causes cell death in stationary phase.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.