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Protein

UPF0761 membrane protein YihY

Gene

yihY

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:EG11851-MONOMER.
ECOL316407:JW3857-MONOMER.

Protein family/group databases

TCDBi9.B.126.2.1. the putative lipid iv exporter (yhjd) family.

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0761 membrane protein YihY
Gene namesi
Name:yihY
Ordered Locus Names:b3886, JW3857
ORF Names:b2268
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11851. yihY.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 38CytoplasmicSequence analysisAdd BLAST38
Transmembranei39 – 61HelicalSequence analysisAdd BLAST23
Topological domaini62 – 100PeriplasmicSequence analysisAdd BLAST39
Transmembranei101 – 120HelicalSequence analysisAdd BLAST20
Topological domaini121 – 140CytoplasmicSequence analysisAdd BLAST20
Transmembranei141 – 163HelicalSequence analysisAdd BLAST23
Topological domaini164 – 182PeriplasmicSequence analysisAdd BLAST19
Transmembranei183 – 205HelicalSequence analysisAdd BLAST23
Topological domaini206 – 211CytoplasmicSequence analysis6
Transmembranei212 – 234HelicalSequence analysisAdd BLAST23
Topological domaini235 – 243PeriplasmicSequence analysis9
Transmembranei244 – 266HelicalSequence analysisAdd BLAST23
Topological domaini267 – 290CytoplasmicSequence analysisAdd BLAST24

GO - Cellular componenti

  • integral component of plasma membrane Source: UniProtKB-HAMAP
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002009811 – 290UPF0761 membrane protein YihYAdd BLAST290

Proteomic databases

PaxDbiP0A8K8.
PRIDEiP0A8K8.

Interactioni

Protein-protein interaction databases

BioGridi4260958. 10 interactors.
STRINGi511145.b3886.

Structurei

3D structure databases

ProteinModelPortaliP0A8K8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0761 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4107S2Z. Bacteria.
COG1295. LUCA.
HOGENOMiHOG000259417.
KOiK07058.
OMAiNKPAKYT.
PhylomeDBiP0A8K8.

Family and domain databases

HAMAPiMF_00672. UPF0761. 1 hit.
InterProiIPR023679. UPF0761_bac.
IPR017039. Virul_fac_BrkB.
[Graphical view]
PfamiPF03631. Virul_fac_BrkB. 1 hit.
[Graphical view]
PIRSFiPIRSF035875. RNase_BN. 1 hit.
TIGRFAMsiTIGR00765. yihY_not_rbn. 1 hit.

Sequencei

Sequence statusi: Complete.

P0A8K8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKTIQDKAR HRTRPLWAWL KLLWQRIDED NMTTLAGNLA YVSLLSLVPL
60 70 80 90 100
VAVVFALFAA FPMFSDVSIQ LRHFIFANFL PATGDVIQRY IEQFVANSNK
110 120 130 140 150
MTAVGACGLI VTALLLMYSI DSALNTIWRS KRARPKIYSF AVYWMILTLG
160 170 180 190 200
PLLAGASLAI SSYLLSLRWA SDLNTVIDNV LRIFPLLLSW ISFWLLYSIV
210 220 230 240 250
PTIRVPNRDA IVGAFVAALL FEAGKKGFAL YITMFPSYQL IYGVLAVIPI
260 270 280 290
LFVWVYWTWC IVLLGAEITV TLGEYRKLKQ AAEQEEDDEP
Length:290
Mass (Da):32,839
Last modified:June 7, 2005 - v1
Checksum:iE027DAB37200CA93
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L19201 Genomic DNA. Translation: AAB03019.1.
U00096 Genomic DNA. Translation: AAD13448.1.
AP009048 Genomic DNA. Translation: BAE77423.1.
PIRiS40830.
RefSeqiNP_418322.1. NC_000913.3.
WP_000920762.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAD13448; AAD13448; b3886.
BAE77423; BAE77423; BAE77423.
GeneIDi948379.
KEGGiecj:JW3857.
eco:b3886.
PATRICi32123275. VBIEscCol129921_3998.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L19201 Genomic DNA. Translation: AAB03019.1.
U00096 Genomic DNA. Translation: AAD13448.1.
AP009048 Genomic DNA. Translation: BAE77423.1.
PIRiS40830.
RefSeqiNP_418322.1. NC_000913.3.
WP_000920762.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0A8K8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260958. 10 interactors.
STRINGi511145.b3886.

Protein family/group databases

TCDBi9.B.126.2.1. the putative lipid iv exporter (yhjd) family.

Proteomic databases

PaxDbiP0A8K8.
PRIDEiP0A8K8.

Protocols and materials databases

DNASUi948379.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD13448; AAD13448; b3886.
BAE77423; BAE77423; BAE77423.
GeneIDi948379.
KEGGiecj:JW3857.
eco:b3886.
PATRICi32123275. VBIEscCol129921_3998.

Organism-specific databases

EchoBASEiEB1797.
EcoGeneiEG11851. yihY.

Phylogenomic databases

eggNOGiENOG4107S2Z. Bacteria.
COG1295. LUCA.
HOGENOMiHOG000259417.
KOiK07058.
OMAiNKPAKYT.
PhylomeDBiP0A8K8.

Enzyme and pathway databases

BioCyciEcoCyc:EG11851-MONOMER.
ECOL316407:JW3857-MONOMER.

Miscellaneous databases

PROiP0A8K8.

Family and domain databases

HAMAPiMF_00672. UPF0761. 1 hit.
InterProiIPR023679. UPF0761_bac.
IPR017039. Virul_fac_BrkB.
[Graphical view]
PfamiPF03631. Virul_fac_BrkB. 1 hit.
[Graphical view]
PIRSFiPIRSF035875. RNase_BN. 1 hit.
TIGRFAMsiTIGR00765. yihY_not_rbn. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYIHY_ECOLI
AccessioniPrimary (citable) accession number: P0A8K8
Secondary accession number(s): P32146, Q2M8I3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: June 7, 2005
Last modified: November 2, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

Was originally (PubMed:8955422) thought to be the tRNA-processing ribonuclease BN (rbn). This was later proven not to be the case (PubMed:15764599).2 Publications

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.