Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Exodeoxyribonuclease 7 small subunit

Gene

xseB

Organism
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.By similarity

Catalytic activityi

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Exonuclease, Hydrolase, Nuclease

Enzyme and pathway databases

BioCyciECOL199310:C0533-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Exodeoxyribonuclease 7 small subunit (EC:3.1.11.6)
Alternative name(s):
Exodeoxyribonuclease VII small subunit
Short name:
Exonuclease VII small subunit
Gene namesi
Name:xseB
Ordered Locus Names:c0533
OrganismiEscherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Taxonomic identifieri199310 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000001410 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 8079Exodeoxyribonuclease 7 small subunitPRO_0000206947Add
BLAST

Interactioni

Subunit structurei

Heterooligomer composed of large and small subunits.By similarity

Protein-protein interaction databases

STRINGi199310.c0533.

Structurei

3D structure databases

ProteinModelPortaliP0A8H0.
SMRiP0A8H0. Positions 8-66.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the XseB family.Curated

Phylogenomic databases

eggNOGiENOG41067QG. Bacteria.
COG1722. LUCA.
HOGENOMiHOG000228798.
KOiK03602.
OMAiAPLNDYK.

Family and domain databases

Gene3Di1.10.287.1040. 1 hit.
HAMAPiMF_00337. Exonuc_7_S. 1 hit.
InterProiIPR003761. Exonuc_VII_S.
[Graphical view]
PfamiPF02609. Exonuc_VII_S. 1 hit.
[Graphical view]
PIRSFiPIRSF006488. Exonuc_VII_S. 1 hit.
ProDomiPD028235. Exonuc_VII_S. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsiTIGR01280. xseB. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0A8H0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPKKNEAPAS FEKALSELEQ IVTRLESGDL PLEEALNEFE RGVQLARQGQ
60 70 80
AKLQQAEQRV QILLSDNEDA SLTPFTPDNE
Length:80
Mass (Da):8,952
Last modified:January 23, 2007 - v2
Checksum:i8B10380D442CADF4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014075 Genomic DNA. Translation: AAN79011.1.
RefSeqiWP_001124935.1. NC_004431.1.

Genome annotation databases

EnsemblBacteriaiAAN79011; AAN79011; c0533.
KEGGiecc:c0533.
PATRICi18279110. VBIEscCol75197_0500.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014075 Genomic DNA. Translation: AAN79011.1.
RefSeqiWP_001124935.1. NC_004431.1.

3D structure databases

ProteinModelPortaliP0A8H0.
SMRiP0A8H0. Positions 8-66.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi199310.c0533.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN79011; AAN79011; c0533.
KEGGiecc:c0533.
PATRICi18279110. VBIEscCol75197_0500.

Phylogenomic databases

eggNOGiENOG41067QG. Bacteria.
COG1722. LUCA.
HOGENOMiHOG000228798.
KOiK03602.
OMAiAPLNDYK.

Enzyme and pathway databases

BioCyciECOL199310:C0533-MONOMER.

Family and domain databases

Gene3Di1.10.287.1040. 1 hit.
HAMAPiMF_00337. Exonuc_7_S. 1 hit.
InterProiIPR003761. Exonuc_VII_S.
[Graphical view]
PfamiPF02609. Exonuc_VII_S. 1 hit.
[Graphical view]
PIRSFiPIRSF006488. Exonuc_VII_S. 1 hit.
ProDomiPD028235. Exonuc_VII_S. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsiTIGR01280. xseB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiEX7S_ECOL6
AccessioniPrimary (citable) accession number: P0A8H0
Secondary accession number(s): P22938
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: January 23, 2007
Last modified: September 7, 2016
This is version 65 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.