Reviewed, UniProtKB/Swiss-Prot P0A8A4 (YDIA_ECOLI)

Names and origin

Protein names

Recommended name:
    Putative phosphotransferase ydiA
    EC=2.7.-.-

Gene names

Name:	ydiA
Ordered Locus Names:	b1703, JW1693

Organism

Escherichia coli (strain K12) [Complete proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	277 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Sequence similarities	Belongs to the pyruvate, phosphate dikinase regulatory protein family.
Sequence caution	The sequence M69116 differs from that shown. Reason: Frameshift at positions 64 and 90.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW kinase activity Inferred from electronic annotation. Source: UniProtKB-KW protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
rluD	P33643	1	EBI-548302,EBI-558026

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 277	277	Putative phosphotransferase ydiA HAMAP MF_01062		PRO_0000196659
Regions
	Nucleotide binding	157 – 164	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	P0A8A4-1 [UniParc]. Last modified June 7, 2005. Version 1. Checksum: 25508DEEC2E342CA	FASTA	277	31,211
	10 20 30 40 50 60 MDNAVDRHVF YISDGTAITA EVLGHAVMSQ FPVTISSITL PFVENESRAR AVKDQIDAIY 70 80 90 100 110 120 HQTGVRPLVF YSIVLPEIRA IILQSEGFCQ DIVQALVAPL QQEMKLDPTP IAHRTHGLNP 130 140 150 160 170 180 NNLNKYDARI AAIDYTLAHD DGISLRNLDQ AQVILLGVSR CGKTPTSLYL AMQFGIRAAN 190 200 210 220 230 240 YPFIADDMDN LVLPASLKPL QHKLFGLTID PERLAAIREE RRENSRYASL RQCRMEVAEV 250 260 270 EALYRKNQIP WINSTNYSVE EIATKILDIM GLSRRMY

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map." Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T., Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T., Mizobuchi K., Mori H., Mori T., Motomura K. , Nakade S., Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y., Wada C., Yamamoto Y., Horiuchi T. DNA Res. 3:363-377(1996) [PubMed: 9097039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]	"The cloning and sequence of the E. coli pps gene." Holzschu D.L., McElver J.A., Liao C.C., Berry A. Submitted (JUN-1991) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-107. Strain: K12.
[5]	"Two promoters control the aroH gene of Escherichia coli." Hudson G.S., Rellos P., Davidson B.E. Gene 102:87-91(1991) [PubMed: 1677907] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 107-277.
[6]	"Structure and regulation of aroH, the structural gene for the tryptophan-repressible 3-deoxy-D-arabino-heptulosonic acid-7-phosphate synthetase of Escherichia coli." Zurawski G., Gunsalus R.P., Brown K.D., Yanofsky C. J. Mol. Biol. 145:47-73(1981) [PubMed: 6167722] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 153-277.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U00096 Genomic DNA. Translation: AAC74773.1. AP009048 Genomic DNA. Translation: BAA15472.2. M69116 Genomic DNA. No translation available. M38266 Genomic DNA. Translation: AAA23496.1. V00261 Genomic DNA. No translation available.
PIR	QQECAD. G64928.
RefSeq	AP_002323.1. NP_416218.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	P0A8A4. 10 interactions.
STRING	P0A8A4.
Genome annotation databases
GeneID	946207.
GenomeReviews	Gene locus JW1693 in contig AP009048_GR. Gene locus b1703 in contig U00096_GR.
KEGG	ecj:JW1693. eco:b1703.
Organism-specific databases
EchoBASE	EB1122.
EcoGene	EG11132. ydiA.
CMR	Search...
Phylogenomic databases
HOGENOM	P0A8A4.
OMA	MERIEAV.
Enzyme and pathway databases
BioCyc	EcoCyc:EG11132-MON.
Gene expression databases
Genevestigator	P0A8A4.
Family and domain databases
HAMAP	MF_01062. [Tree]
InterPro	IPR005177. DUF299_PTrfase_pred. [Graphical view]
Pfam	PF03618. DUF299. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YDIA_ECOLI

Accession

Primary (citable) accession number: P0A8A4
Secondary accession number(s): P03822, P46137, P76203

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 21, 1986
Last sequence update:	June 7, 2005
Last modified:	November 3, 2009
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)