ID   RPIA_ECO57              Reviewed;         219 AA.
AC   P0A7Z2; P27252;
DT   07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT   07-JUN-2005, sequence version 1.
DT   16-JUN-2009, entry version 26.
DE   RecName: Full=Ribose-5-phosphate isomerase A;
DE            EC=5.3.1.6;
DE   AltName: Full=Phosphoriboisomerase A;
DE            Short=PRI;
GN   Name=rpiA; OrderedLocusNames=Z4252, ECs3785;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   MEDLINE=21074935; PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D.,
RA   Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A.,
RA   Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L.,
RA   Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K.,
RA   Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C.,
RA   Welch R.A., Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   MEDLINE=21156231; PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T.,
RA   Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.,
RA   Kuhara S., Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli
RT   O157:H7 and genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- CATALYTIC ACTIVITY: D-ribose 5-phosphate = D-ribulose 5-phosphate.
CC   -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-
CC       ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative
CC       stage): step 1/1.
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SIMILARITY: Belongs to the ribose 5-phosphate isomerase family.
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DR   EMBL; AE005174; AAG58041.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB37208.1; -; Genomic_DNA.
DR   PIR; A98102; A98102.
DR   PIR; E85947; E85947.
DR   RefSeq; NP_289482.1; -.
DR   RefSeq; NP_311812.1; -.
DR   SMR; P0A7Z2; 2-219.
DR   GeneID; 916389; -.
DR   GeneID; 958393; -.
DR   GenomeReviews; AE005174_GR; Z4252.
DR   GenomeReviews; BA000007_GR; ECs3785.
DR   KEGG; ece:Z4252; -.
DR   KEGG; ecs:ECs3785; -.
DR   HOGENOM; P0A7Z2; -.
DR   OMA; P0A7Z2; ADKFICI.
DR   BioCyc; ECOL83334:ECS3785-MON; -.
DR   GO; GO:0004751; F:ribose-5-phosphate isomerase activity; IEA:HAMAP.
DR   GO; GO:0009052; P:pentose-phosphate shunt, non-oxidative branch; IEA:HAMAP.
DR   HAMAP; MF_00170; -; 1.
DR   InterPro; IPR004788; RpiA.
DR   PANTHER; PTHR11934; RpiA; 1.
DR   Pfam; PF06026; Rib_5-P_isom_A; 1.
DR   ProDom; PD005813; RpiA; 1.
DR   TIGRFAMs; TIGR00021; rpiA; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Isomerase.
FT   CHAIN         1    219       Ribose-5-phosphate isomerase A.
FT                                /FTId=PRO_0000158413.
SQ   SEQUENCE   219 AA;  22860 MW;  B53C49CC3DB188BC CRC64;
     MTQDELKKAV GWAALQYVQP GTIVGVGTGS TAAHFIDALG TMKGQIEGAV SSSDASTEKL
     KSLGIHVFDL NEVDSLGIYV DGADEINGHM QMIKGGGAAL TREKIIASVA EKFICIADAS
     KQVDILGKFP LPVEVIPMAR SAVARQLVKL GGRPEYRQGV VTDNGNVILD VHGMEILDPI
     AMENAINAIP GVVTVGLFAN RGADVALIGT PDGVKTIVK
//