P0A7V4 (RS3_ECOL6) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
30S ribosomal protein S3

Gene names

Name:	rpsC
Ordered Locus Names:	c4080

Organism

Escherichia coli O6 [Complete proteome] [HAMAP]

Taxonomic identifier

217992 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	233 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation By similarity. HAMAP MF_01309_B
Subunit structure	Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. Some nascent polypeptide chains are able to cross-link to this protein in situ By similarity.
Sequence similarities	Belongs to the ribosomal protein S3P family. Contains 1 KH type-2 domain.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	small ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 233	232	30S ribosomal protein S3 HAMAP MF_01309_B		PRO_0000130114
Regions
	Domain	39 – 107	69	KH type-2

Sequences

	Sequence		Length	Mass (Da)
	P0A7V4 [UniParc]. Last modified January 23, 2007. Version 2. Checksum: 6D0131A285B7AAB3	FASTA	233	25,983
	10 20 30 40 50 60 MGQKVHPNGI RLGIVKPWNS TWFANTKEFA DNLDSDFKVR QYLTKELAKA SVSRIVIERP 70 80 90 100 110 120 AKSIRVTIHT ARPGIVIGKK GEDVEKLRKV VADIAGVPAQ INIAEVRKPE LDAKLVADSI 130 140 150 160 170 180 TSQLERRVMF RRAMKRAVQN AMRLGAKGIK VEVSGRLGGA EIARTEWYRE GRVPLHTLRA 190 200 210 220 230 DIDYNTSEAH TTYGVIGVKV WIFKGEILGG MAAVEQPEKP AAQPKKQQRK GRK

References

[1]

"Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli." Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D., Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F., Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T., Donnenberg M.S., Blattner F.R. Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002) [PubMed: 12471157] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: O6:H1 / CFT073 / ATCC 700928 / UPEC.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014075 Genomic DNA. Translation: AAN82518.1.
RefSeq	NP_755944.1. NC_004431.1.
3D structure databases
ProteinModelPortal	P0A7V4.
SMR	P0A7V4. Positions 2-233.
ModBase	Search...
Proteomic databases
PRIDE	P0A7V4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000041186; EBESCP00000039535; EBESCG00000040236.
GeneID	1039824.
GenomeReviews	Gene locus c4080 in contig AE014075_GR.
KEGG	ecc:c4080.
PATRIC	18285924. VBIEscCol75197_3838.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000011227.
HOGENOM	HBG748975.
OMA	TIGIKVW.
ProtClustDB	PRK00310.
Family and domain databases
HAMAP	MF_01309_B. Ribosomal_S3_B. [Tree]
InterPro	IPR004087. KH. IPR015946. KH_dom-like_a/b. IPR009019. KH_prok-type. IPR004044. KH_type_2. IPR005704. Ribosomal_S3_bac. IPR001351. Ribosomal_S3_C. IPR018280. Ribosomal_S3_CS. IPR008282. Ribosomal_S3_N. [Graphical view]
Gene3D	G3DSA:3.30.300.20. KH_prok. 1 hit. G3DSA:3.30.1140.32. Ribosomal_S3_C. 1 hit.
KO	K02982.
Pfam	PF07650. KH_2. 1 hit. PF00189. Ribosomal_S3_C. 1 hit. PF00417. Ribosomal_S3_N. 1 hit. [Graphical view]
SMART	SM00322. KH. 1 hit. [Graphical view]
SUPFAM	SSF54814. KH_prok. 1 hit. SSF54821. Ribosomal_S3_C. 1 hit.
TIGRFAMs	TIGR01009. RpsC_bact. 1 hit.
PROSITE	PS50823. KH_TYPE_2. 1 hit. PS00548. RIBOSOMAL_S3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RS3_ECOL6

Accession

Primary (citable) accession number: P0A7V4
Secondary accession number(s): P02352

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 21, 1986
Last sequence update:	January 23, 2007
Last modified:	January 25, 2012
This is version 47 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program