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Protein

50S ribosomal protein L31 type B

Gene

ykgM

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cellular response to zinc ion starvation Source: EcoCyc
  • translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciEcoCyc:G6167-MONOMER.
ECOL316407:JW5035-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L31 type B
Gene namesi
Name:ykgM
Synonyms:rpmE2
Ordered Locus Names:b0296, JW5035
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14326. ykgM.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Disruption phenotypei

Grows poorly in the absence of zinc.1 Publication

Chemistry

ChEMBLiCHEMBL2363135.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 878750S ribosomal protein L31 type BPRO_0000173222Add
BLAST

Proteomic databases

PaxDbiP0A7N1.
PRIDEiP0A7N1.

2D gel databases

SWISS-2DPAGEP0A7N1.

Expressioni

Inductioni

Maximally induced 30 minutes under zinc-limiting conditions, still induced in stationary phase; repressed by the zinc uptake regulation protein Zur. Probably part of the rpmE2-rpmJ2 operon.3 Publications

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit.By similarity

Protein-protein interaction databases

BioGridi4263546. 10 interactions.
IntActiP0A7N1. 2 interactions.
STRINGi511145.b0296.

Structurei

3D structure databases

ProteinModelPortaliP0A7N1.
SMRiP0A7N1. Positions 1-77.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105NRA. Bacteria.
COG0254. LUCA.
HOGENOMiHOG000284894.
InParanoidiP0A7N1.
KOiK02909.
OMAiFKDMSND.
OrthoDBiEOG6DVJZM.
PhylomeDBiP0A7N1.

Family and domain databases

HAMAPiMF_00502. Ribosomal_L31_2.
InterProiIPR002150. Ribosomal_L31.
IPR027493. Ribosomal_L31_B.
[Graphical view]
PfamiPF01197. Ribosomal_L31. 1 hit.
[Graphical view]
PRINTSiPR01249. RIBOSOMALL31.
TIGRFAMsiTIGR00105. L31. 1 hit.
PROSITEiPS01143. RIBOSOMAL_L31. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P0A7N1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKPNIHPEYR TVVFHDTSVD EYFKIGSTIK TDREIELDGV TYPYVTIDVS
60 70 80
SKSHPFYTGK LRTVASEGNV ARFTQRFGRF VSTKKGA
Length:87
Mass (Da):9,920
Last modified:June 7, 2005 - v1
Checksum:i10D231F36CECBE39
GO

Sequence cautioni

The sequence AAB18024.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U73857 Genomic DNA. Translation: AAB18024.1. Different initiation.
U00096 Genomic DNA. Translation: AAC73399.1.
AP009048 Genomic DNA. Translation: BAE76081.1.
PIRiH64755.
RefSeqiNP_414830.1. NC_000913.3.
WP_000803998.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73399; AAC73399; b0296.
BAE76081; BAE76081; BAE76081.
GeneIDi944960.
KEGGiecj:JW5035.
eco:b0296.
PATRICi32115717. VBIEscCol129921_0301.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U73857 Genomic DNA. Translation: AAB18024.1. Different initiation.
U00096 Genomic DNA. Translation: AAC73399.1.
AP009048 Genomic DNA. Translation: BAE76081.1.
PIRiH64755.
RefSeqiNP_414830.1. NC_000913.3.
WP_000803998.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP0A7N1.
SMRiP0A7N1. Positions 1-77.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263546. 10 interactions.
IntActiP0A7N1. 2 interactions.
STRINGi511145.b0296.

Chemistry

ChEMBLiCHEMBL2363135.

2D gel databases

SWISS-2DPAGEP0A7N1.

Proteomic databases

PaxDbiP0A7N1.
PRIDEiP0A7N1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73399; AAC73399; b0296.
BAE76081; BAE76081; BAE76081.
GeneIDi944960.
KEGGiecj:JW5035.
eco:b0296.
PATRICi32115717. VBIEscCol129921_0301.

Organism-specific databases

EchoBASEiEB4072.
EcoGeneiEG14326. ykgM.

Phylogenomic databases

eggNOGiENOG4105NRA. Bacteria.
COG0254. LUCA.
HOGENOMiHOG000284894.
InParanoidiP0A7N1.
KOiK02909.
OMAiFKDMSND.
OrthoDBiEOG6DVJZM.
PhylomeDBiP0A7N1.

Enzyme and pathway databases

BioCyciEcoCyc:G6167-MONOMER.
ECOL316407:JW5035-MONOMER.

Miscellaneous databases

PROiP0A7N1.

Family and domain databases

HAMAPiMF_00502. Ribosomal_L31_2.
InterProiIPR002150. Ribosomal_L31.
IPR027493. Ribosomal_L31_B.
[Graphical view]
PfamiPF01197. Ribosomal_L31. 1 hit.
[Graphical view]
PRINTSiPR01249. RIBOSOMALL31.
TIGRFAMsiTIGR00105. L31. 1 hit.
PROSITEiPS01143. RIBOSOMAL_L31. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence of minutes 4-25 of Escherichia coli."
    Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M., Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D., Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.
    Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "Comparative genomics of bacterial zinc regulons: enhanced ion transport, pathogenesis, and rearrangement of ribosomal proteins."
    Panina E.M., Mironov A.A., Gelfand M.S.
    Proc. Natl. Acad. Sci. U.S.A. 100:9912-9917(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: DISCUSSION OF POSSIBLE REGULATION.
    Strain: K12 / MG1655 / ATCC 47076.
  5. "Severe zinc depletion of Escherichia coli: roles for high affinity zinc binding by ZinT, zinc transport and zinc-independent proteins."
    Graham A.I., Hunt S., Stokes S.L., Bramall N., Bunch J., Cox A.G., McLeod C.W., Poole R.K.
    J. Biol. Chem. 284:18377-18389(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION, DISRUPTION PHENOTYPE.
    Strain: K12 / MG1655 / ATCC 47076.
  6. "Small stress response proteins in Escherichia coli: proteins missed by classical proteomic studies."
    Hemm M.R., Paul B.J., Miranda-Rios J., Zhang A., Soltanzad N., Storz G.
    J. Bacteriol. 192:46-58(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION, OPERON STRUCTURE.
    Strain: K12 / MG1655 / ATCC 47076.
  7. Cited for: INDUCTION.
    Strain: BW21135.

Entry informationi

Entry nameiRL31B_ECOLI
AccessioniPrimary (citable) accession number: P0A7N1
Secondary accession number(s): P71302, Q2MCC5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: June 7, 2005
Last modified: January 20, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.